Results 201 to 210 of about 510,342 (390)

Forelimb Motor Learning and Memory Consolidation Drives Distinct Oligodendrocyte Plasticity to Regulate Task‐related Neuronal Activity

Advanced Science, EarlyView.
Genetic and chemical tracking of oligodendrogenesis, combining fiber photometric neuronal activity recording, reveals that distinct oligodendrocyte plasticities are adopted during different phases of motor learning to fine‐tune task‐related neuronal activity, with a preferential involvement of oligodendrogenesis suppression and node lengthening (type 2
Shuming Wang, Nuo Xu, Wenwen Wang, Yongxiang He, Yuqian Yang, Liuning Zhang, Yanping Zou, Yuehua He, Huiliang Li, Liang Gao, Lin Xiao   +10 more
wiley   +1 more source

Effect of JAK inhibitors on release of CXCL9, CXCL10 and CXCL11 from human airway epithelial cells [PDF]

, 2015
Barnes, PJ, Donnelly, LE, Fenwick, PS, Macedo, P   +3 more
core   +1 more source

Characterization of the dexamethasone-induced inhibitor of plasminogen activator in HTC hepatoma cells.

, 1986
Patrick L. Coleman, Paresh D. Patel, B J Cwikel, U M Rafferty, R Sznycer-Laszuk, Thomas Gelehrter   +5 more
openalex   +1 more source

Carfilzomib, lenalidomide, and dexamethasone for relapsed multiple myeloma.

New England Journal of Medicine, 2015
A. Stewart, S. Rajkumar, M. Dimopoulos, Tamás Masszi, I. Spicka, A. Oriol, R. Hajek, L. Rosiñol, David S. Siegel, Georgi G. Mihaylov, V. Goranova-Marinova, P. Rajnics, A. Suvorov, R. Niesvizky, A. Jakubowiak, J. San-Miguel, Heinz Ludwig, Michael Wang, V. Maisnar, J. Minařík, W. Bensinger, M. Mateos, Dina Ben-Yehuda, V. Kukreti, N. Zojwalla, Margaret E. Tonda, Xinqun Yang, Biao Xing, P. Moreau, A. Palumbo   +29 more
semanticscholar   +1 more source

TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition

Advanced Science, EarlyView.
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang, Ende Wu, Weibin Liu, Ling Zeng, Neng Ling, Hongmei Wang, Zhixing Li, Shuang Yao, Tonghe Pan, Xuanwen Li, Yate Huang, Xiaojing Li, Yunhai Tu, Wentao Yan, Jianzhang Wu, Mao Ye, Wencan Wu   +16 more
wiley   +1 more source

In Vivo T Cell Depletion With Dexamethasone Reduces Graft Versus Host Disease (GVHD) With Minimal Side Effects and No Additional Risk of Early Relapse After Allogeneic Peripheral Blood Stem Cell (PBSC) Transplantation

, 2011
Raquel Innis‐Shelton, Khairil Ashraff, Y. Li, Nalini Mehta, Donna Salzman, Arabella B. Tilden, William P. Vaughan, Lawrence S. Lamb   +7 more
openalex   +1 more source

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

Advanced Science, EarlyView.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun, Miriayi Alimujiang, Wenfei Li, Shuqin Chen, Yingying Su, Tingting Hu, Xuhong Lu, Yafen Ye, Ningning Bai, Fan Hu, Xiaoya Li, Rongrong Xu, Jun Xu, Jiarui Zhao, Yan Lu, Xiaojing Ma, Ying Yang   +16 more
wiley   +1 more source

Investigating Why Comparing Intravenous and Perineural Dexamethasone Is Scientifically Unfounded. [PDF]

Cureus
Sonawane K.
europepmc   +1 more source

Bortezomib or high-dose dexamethasone for relapsed multiple myeloma.

New England Journal of Medicine, 2005
P. Richardson, P. Sonneveld, M. Schuster, D. Irwin, E. Stadtmauer, T. Facon, J. Harousseau, D. Ben-yehuda, S. Lonial, H. Goldschmidt, D. Reece, J. San-Miguel, J. Bladé, M. Boccadoro, J. Cavenagh, W. Dalton, A. Boral, D. Esseltine, Jane Porter, D. Schenkein, K. Anderson   +20 more
semanticscholar   +1 more source

TREM2‐Mediated Cholesterol Efflux in Macrophages Inhibits Anti‐Tumor Immunity via Limitation of CD4+ T and NK Cells

Advanced Science, EarlyView.
Impaired anti‐tumor immunity is mediated by TREM2 + macrophages in non‐small cell lung cancer. TREM2 + macrophages prevent anti‐tumor immunity depending on the limitation of CD4 + T and NK cells. TREM2 promotes cholesterol efflux via ABCA1 to limit the production of CX3CL1 in macrophages.
Yunhan Wang, Weina Yu, Xinxin Wang, Qitai Zhao, Qingyang Lei, Aitian Li, Shasha Liu, Tian Wang, Li Yang, Yi Zhang   +9 more
wiley   +1 more source