Results 201 to 210 of about 361,176 (290)

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Dexamethasone Admixture for Hypersensitivity Prevention in Botulinum Toxin Type A Treatment: A Case Report. [PDF]

J Cosmet Dermatol
Jia X, Liang Y, Chen Q, Hu J.
europepmc   +1 more source

Prospective cohort study evaluating risk factors for the development of pasture-associated laminitis in the United Kingdom [PDF]

, 2016
Arita, Asplin, Bailey, Bailey, Beltowski, Blakesley, Borer, Bremer, Brooks, Carter, Cywinska, Dallmeier, Efstathiou, El-Mesallamy, Fesus, Finding, Firshman, Frank, Frank, Giles, Giordano, Greiner, Heinrichs, Henneke, Hinckley, Holbrook, Hotta, Huang, Ingelsson, Johnson, Kearns, Kim, Kullmann, Laat, Lam, Lavoie-Lamoureux, Lim, Luszczynski, Lygren, Macieira, Maleki, Mattu, Morgan, Orth, Ouchi, Pischon, Pleasant, Pollock, Popot, Pratt, Ragab, Reimers, Robin, Rosen, Ruan, Ruan, Ryu, Salazar-Ortiz, Salonen, Sandhu, Schultz, Smith, Stephenson, Takiguchi, Torres, Treiber, Treiber, Treiber, Treiber, Troncoso, Trujillo, Wannamethee, Wray, Wyse, Yang   +74 more
core   +2 more sources

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Corticosteroids ameliorate CAR T-cell-induced cytokine-release syndrome without inhibiting multiple myeloma treatment. [PDF]

J Immunother Cancer
Amatya C, Weissler KA, Lam N, Natrakul DA, Brudno JN, Cutmore LC, Mikkilineni L, Kochenderfer JN.   +7 more
europepmc   +1 more source

Effect of JAK inhibitors on release of CXCL9, CXCL10 and CXCL11 from human airway epithelial cells [PDF]

, 2015
Barnes, PJ, Donnelly, LE, Fenwick, PS, Macedo, P   +3 more
core   +1 more source

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

A Long-Acting Combination Nerve Block in Rhinoplasty to Minimize Postoperative Opioid Use. [PDF]

Aesthet Surg J Open Forum
Cheung MM, Shah AR.
europepmc   +1 more source

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

British Journal of Clinical Pharmacology, EarlyView.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup, Michel Tod, Laurent Bourguignon   +2 more
wiley   +1 more source

Risk factors for venous thromboembolism in newly diagnosed multiple myeloma patients based on thrombosis prophylaxis. [PDF]

Ann Hematol
Zhao S, Wang Y, Jia J, Bu Q, Chen W.
europepmc   +1 more source