Results 261 to 270 of about 237,941 (312)
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Bioavailability of dexamethasone; II. Dexamethasone phosphate
Clinical Pharmacology & Therapeutics, 1975Plasma levels of dexamethasone phosphate (DP) and dexamethasone free alcohol (DA) were determined by a modification of existing radioimmunoassay methodology following intravenous administration of DP in man. Areas under DA plasma profiles were a linear function of DP dosage over the 40‐fold range 0.05 to 2.0 mg/kg, and, by comparison with values ...
K. C. Yeh +4 more
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Archives of Dermatology, 1959
Dexamethasone is 9-α-fluoro,16-α-methylprednisolone. * It is one of a group of prednisolone analogues synthesized and studied by Arth and his co-workers 1,2 in the continuing search for modifications of hydrocortisone which would afford increased anti-inflammatory and antiallergic activity but would produce minimal mineral imbalance and the other ...
Blau S, Norman B. Kanof
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Dexamethasone is 9-α-fluoro,16-α-methylprednisolone. * It is one of a group of prednisolone analogues synthesized and studied by Arth and his co-workers 1,2 in the continuing search for modifications of hydrocortisone which would afford increased anti-inflammatory and antiallergic activity but would produce minimal mineral imbalance and the other ...
Blau S, Norman B. Kanof
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Dexamethasone in adenotonsillectomy
International Journal of Pediatric Otorhinolaryngology, 1996Edema contributes substantially to the postoperative discomfort and morbidity of adenotonsillectomy. In a double-blind study, 58 children undergoing adenotonsillectomy were given a single intraoperative dose of either dexamethasone or saline. The steroid markedly affected the postoperative course in the first day after surgery.
Josephine J. Templeton +3 more
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Dexamethasone and Osteonecrosis
Australian and New Zealand Journal of Medicine, 1981Abstract: Four cases are reported in whom osteonecrosis followed after Dexamethasone was administered in high dosage for a short time to mduce cerebral and spinal cord oedema. Although corticosteroids have been implicated in the development of osteonecrosis, the delay from corticosteroid administration to the development of symptoms (9–30 months ...
K. A. Black, E. T. Owen, M. S. Khangure
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Plasma dexamethasone concentrations and the dexamethasone suppression test
Biological Psychiatry, 1990Altered bioavailability or altered pharmacokinetics of dexamethasone (dex) may contribute to a positive Dexamethasone Suppression Test (DST) in psychiatric patients. We measured plasma dex and plasma cortisol concentrations in 32 patients with primary major depressive disorder (MDD), 14 patients with other psychiatric disorders, and 16 normal controls.
K. Ranga +5 more
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The dexamethasone suppression test: Importance of dexamethasone concentrations
Biological Psychiatry, 1987Plasma dexamethasone concentrations and cortisol response to dexamethasone were measured in 29 normal healthy volunteers, 23 depressed patients, and 10 patients with anorexia nervosa at 4:00 PM postdexamethasone. In each of the 3 groups, nonsuppressors had lower dexamethasone concentrations than suppressors. Of the subjects with plasma dexamethasone at
N. Biddle +4 more
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Dexamethasone Suppression Test and Plasma Dexamethasone Levels in Bulimia
Archives of General Psychiatry, 1987A 1-mg dexamethasone suppression test (DST) was carried out in 66 women with bulimia and in 26 age- and sex-matched controls. Blood samples were obtained at 4 PM on the day following dexamethasone ingestion, and levels of cortisol and of dexamethasone in the plasma were measured.
David C. Lindy +6 more
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Shortened Dexamethasone Half-life in Depressed Dexamethasone Nonsuppressors
Archives of General Psychiatry, 1986To the Editor.— A variety of technical and medical factors have been identified that may invalidate results of the dexamethasone suppression test (DST). Our unit1,2and other investigators3-5have reported that plasma dexamethasone concentrations were significantly lower in DST nonsuppressors than in suppressors.
Klaus Wiedemann +2 more
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The effect of serum dexamethasone concentrations in the dexamethasone suppression test
Biological Psychiatry, 1986Serum dexamethasone and cortisol concentrations were measured in a sample of 98 psychiatric inpatients during the course of the 1-mg oral overnight Dexamethasone Suppression Test (DST). Suppressors were found to have significantly higher serum dexamethasone concentrations than nonsuppressors at each time of sampling (8:00 AM, 4:00 PM, and 11:00 PM ...
Vaughan J. Carr +2 more
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