Results 271 to 280 of about 496,062 (355)

Artificial intelligence modelling of tyrosine kinase inhibitors at risk of malabsorption and bioavailability‐enhancing strategies

British Journal of Clinical Pharmacology, EarlyView.
Aims The study aims to predict and improve the absorption of tyrosine kinase inhibitors (TKIs) in patients with malabsorption issues, particularly those who have undergone bariatric surgery or are using proton‐pump inhibitors. The research involves 2 main components: the development of an artificial intelligence (AI) model to identify TKIs that are ...
Daan W. Huntjens, Olivier J. M. Béquignon, Stefanie D. Krens, Mark Löwenberg, Martine E. D. Chamuleau, Remco J. Molenaar, Anita M. G. Kramers, Marianne A. Kuijvenhoven, Imke H. Bartelink   +8 more
wiley   +1 more source

Randomized blinded pilot trial of corticosteroid after mild-moderate anaphylaxis to prevent recurrence. [PDF]

Medicine (Baltimore)
Al Sayyed R, Alansari K, Alansari K.
europepmc   +1 more source

Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis.

New England Journal of Medicine, 2016
J. Beardsley, M. Wolbers, Freddie M Kibengo, Abu-Baker Ggayi, A. Kamali, N. T. Cuc, T. Q. Binh, N. Chau, J. Farrar, L. Merson, Lan Phuong, G. Thwaites, N. van Kinh, P. T. Thuy, W. Chierakul, S. Siriboon, E. Thiansukhon, Satrirat Onsanit, Watthanapong Supphamongkholchaikul, A. Chan, R. Heyderman, E. Mwinjiwa, J. V. van Oosterhout, D. Imran, H. Basri, M. Mayxay, D. Dance, P. Phimmasone, S. Rattanavong, D. Lalloo, J. Day   +30 more
semanticscholar   +1 more source

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

Comparative Studies on Dexamethasone and Prednisolone Esters : Carrageenin Edema-Depressive Effect of Phosphates and Sulfates and Plasma Concentrations of the Corticosteroids

, 1971
Haruo Kitagawa, Tetsuro Mohri, MASATOSHI KITAGAWA   +2 more
openalex   +2 more sources

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Innovations in Dental Implants Integration: Optimizing dental implants performance utilizing stem cells and coatings

Biotechnology Progress, EarlyView.
Abstract The last two decades, between 2000 and 2024, significant steps were achieved regarding the interaction between various stem cells and titanium implant surfaces to improve dental implant integration. This literature review focuses on the potential effects of (i) bone marrow mesenchymal stem cells (BMSCs), (ii) periodontal ligament stem cells ...
Ioannis Tsamesidis, Athanasios Christodoulou, Evangelia Stalika, Georgia K. Pouroutzidou, Eleana Kontonasaki   +4 more
wiley   +1 more source

Evaluation of triply periodic minimal surface geometries in 3D‐printed PLA scaffolds for chondrogenic differentiation

Biotechnology Progress, EarlyView.
Abstract Triply periodic minimal surface (TPMS) scaffolds are gaining attention in tissue engineering due to their continuous and interconnected porous architecture. In this study, three TPMS geometries—Gyroid, Diamond, and I‐WP—were fabricated from polylactic acid (PLA) using fused deposition modeling (FDM), with all scaffolds designed to maintain the
Mahmut Alp Kılıç, Mustafa Akyürek, Roozbeh Abidnejad, Alp Karakoç   +3 more
wiley   +1 more source

Targeting degradation of IKZF1 and IKZF3 through modulation of the E3 ligase substrates in the context of cellular therapies for multiple myeloma. [PDF]

Biomark Res
Kegyes D, Bancos A, Tigu AB, Rus I, Dima D, Cenariu D, Nistor M, Munteanu R, Gulei D, Tanase A, Colita A, Buzoianu A, Iuga C, Zdrenghea M, Terpos E, Ciurea SO, Ciechanover A, Einsele H, Tomuleasa C.   +18 more
europepmc   +1 more source

Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America.

New England Journal of Medicine, 2007
D. Weber, Christine I. Chen, R. Niesvizky, Michael L. Wang, A. Belch, E. Stadtmauer, D. Siegel, I. Borrello, S. Rajkumar, A. Chanan-Khan, S. Lonial, Zhinuan Yu, J. Patin, Marta Olesnyckyj, J. Zeldis, R. Knight   +15 more
semanticscholar   +1 more source