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The plasma dexamethasone “window” and the dexamethasone suppression test in depression
Biological Psychiatry, 1987Benaim S, Page C (1984): The prognostic significance of lithium induced hypothyroidism and the importance of a positive thyroid antibody titre in recurrent affective illness. Proceedings of the CINP, abstract no. F-182. Fischetti B (1962): Pharmacological influences on thyroid activity. Arch ltal Sci Pharmacol 12:33109.
Gordon Johnson +3 more
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Dexamethasone metabolism in dexamethasone suppression test suppressors and nonsuppressors
Biological Psychiatry, 2000Variable dexamethasone kinetics is a possible confound in the dexamethasone suppression test. Modifications to include dexamethasone plasma levels and specific dexamethasone "windows" have been proposed. Our study aims to validate our proposed dexamethasone windows in an independent sample of 121 subjects.We performed dexamethasone suppression tests in
Kumari Verghese +3 more
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Der Anaesthesist, 2019
Dexamethasone is a synthetic steroid that has been used for many years in the clinical routine due to its anti-inflammatory, anti-allergic and immunosuppressive properties. Furthermore, dexamethasone has been used for a long time for prophylaxis and treatment of chemotherapy-induced nausea and vomiting.
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Dexamethasone is a synthetic steroid that has been used for many years in the clinical routine due to its anti-inflammatory, anti-allergic and immunosuppressive properties. Furthermore, dexamethasone has been used for a long time for prophylaxis and treatment of chemotherapy-induced nausea and vomiting.
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Dexamethasone and Prolactin in Depression
Archives of General Psychiatry, 1982To the Editor. —There has been considerable interest in the dexamethasone suppression test (DST) in the study of endogenous depression, or the melancholia variant thereof. 1 Approximately 40% to 60% of patients with depression fail to lower plasma cortisol levels to 5.0 μs/DL 8, 16, or 24 hours after a 1.0-mg dose of dexamethasone.
Herbert Y. Meltzer +2 more
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Dexamethasone Concentrations and the Dexamethasone Suppression Test in Psychiatric Disorders
British Journal of Psychiatry, 1986The dexamethasone suppression test (DST) has been widely used in psychiatry as a laboratory aid for the diagnosis of endogenous depression; failure to suppress serum cortisol levels is interpreted as confirming a clinical diagnosis of endogenous depression.
Judy Gilliland +3 more
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Brain Damage and Dexamethasone?
Pediatrics, 2000To the Editor. The conclusion reached by O'Shea and colleagues,1that postnatal dexamethasone is associated with an increased risk of cerebral palsy, is undermined by important differences in gestational age and in the use of antenatal steroids between the dexamethasone-treated group and the placebo group.
Wright, NP, Wales, JKH
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Interaction of Dexamethasone with Phenytoin
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1991Phenytoin and dexamethasone are frequently administered concurrently to prevent consequences of central nervous system pathology. Limited and conflicting data are available regarding an interaction between the agents. A patient receiving dexamethasone required a daily phenytoin dose of greater than 10 mg/kg to maintain the phenytoin serum concentration
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Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19
Nature Medicine, 2021Sarthak Sinha +2 more
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