Results 41 to 50 of about 515,791 (281)

Comparison of the efficacy of cardamom (Elettaria cardamomum) with pioglitazone on dexamethasone-induced hepatic steatosis, dyslipidemia, and hyperglycemia in albino rats

Journal of Advanced Pharmaceutical Technology & Research, 2015
To evaluate the efficacy of cardamom with pioglitazone on dexamethasone-induced hepatic steatosis, dyslipidemia, and hyperglycemia in albino rats. There were four groups of 6 rats each.
G M Nitasha Bhat, Nagendra Nayak, K Vinodraj, N Chandralekha, Paul Mathai, J Cherian   +5 more
doaj   +1 more source

Qualitative and Quantitative Analysis of Dexamethasone in Rheumatic Pain Herbal Medicine Using Thin-Layer Chromatography (TLC) – Densitometry

Journal of Fundamental and Applied Pharmaceutical Science, 2021
Chemical medicine is chemical substances that is used as the main ingredient of chemical drugs. This compound is usually added to herbal medicine preparation to strengthen the indication of the traditional medicine.Chemical medicine was prohibited from ...
Desy Ayu Irma Permatasari, Novita Kurniasri, Muladi Putra Mahardika   +2 more
doaj   +1 more source

Longer term follow-up of the randomized phase III trial SWOG S0777: bortezomib, lenalidomide and dexamethasone vs. lenalidomide and dexamethasone in patients (Pts) with previously untreated multiple myeloma without an intent for immediate autologous stem cell transplant (ASCT)

Blood Cancer Journal, 2020
SWOG S0777, a randomized phase III trial, compared bortezomib, lenalidomide and dexamethasone (VRd) with lenalidomide and dexamethasone (Rd). This updated analysis includes 460 patients evaluable for survival endpoints: 225 eligible and analyzable ...
Brian G. M. Durie, A. Hoering, R. Sexton, M. Abidi, J. Epstein, S. Rajkumar, A. Dispenzieri, S. Kahanic, M. Thakuri, F. Reu, Christopher M. Reynolds, R. Orlowski, B. Barlogie   +12 more
semanticscholar   +1 more source

Anti-Inflammatory Treatment of COVID-19 Pneumonia With Tofacitinib Alone or in Combination With Dexamethasone is Safe and Possibly Superior to Dexamethasone as a Single Agent in a Predominantly African American Cohort

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2021
Objective: To explore the survival benefit of tofacitinib in addition to dexamethasone in hospitalized patients treated for coronavirus disease 2019 (COVID-19)–related pneumonia.
Maroun E. Hayek, MD, Michael Mansour, MD, Harrison Ndetan, MPH, MD, PhD, Quentin Burkes, PharmD, Robert Corkern, MD, Ammar Dulli, MD, Reya Hayek, BS, Karim Parvez, MD, Satwinder Singh, MD   +8 more
doaj   +1 more source

The Influence of Hyperactivity of the Hypothalamic-pituitary-adrenal Axis and Hyperglycemia on the 5-HT2A Receptor-mediated Wet-dog Shake Responses in Rats [PDF]

, 2007
Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis induces hyperglycemia and serotonin (5-HT)2A receptor supersensitivity. In the present study, to investigate the effect of hyperglycemia on the function of 5-HT2A receptors, we compared the 5-
Amano, Manabu, Araki, Hiroaki, Gomita, Yutaka, Kawasaki, Hiromu, Kitamura, Yoshihisa, Suemaru, Katsuya, Umeda, Yuichi, Yamaguchi, Takumi   +7 more
core   +1 more source

Trial of Dexamethasone for Chronic Subdural Hematoma.

New England Journal of Medicine, 2020
BACKGROUND Chronic subdural hematoma is a common neurologic disorder that is especially prevalent among older people. The effect of dexamethasone on outcomes in patients with chronic subdural hematoma has not been well studied.
P. Hutchinson, E. Edlmann, D. Bulters, A. Zolnourian, P. Holton, N. Suttner, Kevin Agyemang, S. Thomson, I. Anderson, Y. Al-Tamimi, D. Henderson, P. Whitfield, Monica Gherle, P. Brennan, Annabel Allison, E. Thelin, S. Tarantino, B. Pantaleo, K. Caldwell, C. Davis-Wilkie, H. Mee, E. Warburton, G. Barton, A. Chari, H. Marcus, A. King, A. Belli, P. Myint, Ian Wilkinson, T. Santarius, C. Turner, S. Bond, A. Kolias   +32 more
semanticscholar   +1 more source

Treatment of oral chronic graft-versus-host disease: a retrospective cohort study

Einstein (São Paulo), 2021
Objective The aim of this study was to evaluate patients with complete response of oral chronic graft-versus-host disease to immunosuppressive treatment.
Gabriela de Assis Ramos, Taísa Domingues Boehmer Leite, Camila Brandão Lobo, Paulo Sérgio da Silva Santos, Maria Claudia Rodrigues Moreira, Héliton Spindola Antunes   +5 more
doaj   +2 more sources

Glucocorticoids for human skin: New aspects of the mechanism of action [PDF]

, 2005
Topical glucocorticoids have always been considered first-line drugs for inflammatory diseases of the skin and bronchial system. Applied systemically, glucocorticoids are used for severe inflammatory and immunological diseases and the inhibition of ...
Ahmed, M., Holtje, H. D., Kleuser, B., Korting, Hans Christian, Schäfer-Korting, Monika   +4 more
core   +1 more source

A novel human glucocorticoid receptor SNP results in increased transactivation potential. [PDF]

, 2017
Glucocorticoids are one of the most widely used therapeutics in the treatment of a variety of inflammatory disorders. However, it is known that there are variable patient responses to glucocorticoid treatment; there are responders and non-responders, or ...
Cho, Kiho, Green, Tajia L, Greenhalgh, David G, Leventhal, Stacey M, Lim, Debora, Tung, Kelly   +5 more
core   +3 more sources

Dexamethasone Sensitizes Cancer Stem Cells to Gemcitabine and 5-Fluorouracil by Increasing Reactive Oxygen Species Production through NRF2 Reduction

Life, 2021
Cancer stem cells (CSCs) have high tumor-initiating capacity and are resistant to chemotherapeutic reagents; thus eliminating CSCs is essential to improving the prognosis.
Shuhei Suzuki, Masahiro Yamamoto, Tomomi Sanomachi, Keita Togashi, Asuka Sugai, Shizuka Seino, Takashi Yoshioka, Masashi Okada, Chifumi Kitanaka   +8 more
doaj   +1 more source