Results 41 to 50 of about 3,454 (177)

Dexamethasone Implant in Patients with Diabetic Macular Edema Resistant to Anti-VEGF Therapy

Türk Oftalmoloji Dergisi, 2019
Objectives:To investigate the efficacy of single dose intravitreal dexamethasone implant in patients with diabetic macular edema (DME) resistant to anti-VEGF therapy.Materials and Methods:Twenty eyes of 14 patients (8 male, 6 female; mean age, 65±5.7 ...
Serhad Nalçacı, Cezmi Akkın, Filiz Afrashi   +2 more
doaj   +1 more source

Rhegmatogenous Retinal Detachment with a High Risk of Proliferative Vitreoretinopathy Treated with Episcleral Surgery and an Intravitreal Dexamethasone 0.7-mg Implant

Case Reports in Ophthalmology, 2013
Purpose: To report a case of rhegmatogenous retinal detachment with a high risk of proliferative vitreoretinopathy (PVR) effectively treated with episcleral surgery and an intravitreal dexamethasone 0.7-mg implant.
Michele Reibaldi, Andrea Russo, Antonio Longo, Vincenza Bonfiglio, Maurizio G. Uva, Caterina Gagliano, Mario D. Toro, Teresio Avitabile   +7 more
doaj   +1 more source

Paraneoplastic and Autoimmune Retinopathy Presenting as Isolated Neuro‐Ophthalmic Dysfunction: Two Cases

Clinical and Experimental Neuroimmunology, Volume 17, Issue 4, November 2026.
ABSTRACT Background Paraneoplastic and autoimmune retinopathies can cause progressive visual loss before structural ophthalmic or neurologic findings are diagnostic. Case Presentation A 66‐year‐old woman developed bilateral visual decline and was diagnosed with small‐cell lung cancer‐associated paraneoplastic neuroretinal dysfunction, with persistent ...
Alan B. Dogan, Dean Neutel, Anthony L. Loschner   +2 more
wiley   +1 more source

Comparison of Efficacy of Suprachoroidal Triamcinolone Acetonide Alone or in Combination With Intravitreal Bevacizumab for Treatment of Diabetic Macular Edema: A Prospective Comparative Study

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims This study was designed to evaluate the safety, efficacy, and durability of suprachoroidal triamcinolone acetonide, administered either alone or in combination with intravitreal bevacizumab (IVB), in the treatment of diabetic macular edema (DME). Methods This prospective comparative interventional study was conducted in the
Muhammad Tahir Ghaffar, Asad Aslam Khan, Mohammad Hasan Bokhari, Tahseen Mahmood Majhu, Faisal Anwar, Chaudhry Nasir Ahmed, Aalaa Saleh   +6 more
wiley   +1 more source

Evaluation of efficacy dexamethasone intravitreal implant compared to treatment with anti-VEGF in the treatment of diabetic macular edema

Senses and Sciences, 2014
Objective: The study compares the effectiveness of an intravitreal slow-release dexamethasone implant respect to an intravitreal injection of a anti-VEGF, ranibizumab, in the treatment of diabetic macular edema (DME).
Elena Pacella, Giuseppe La Torre, Paolo Turchetti, Concetta Merisola, Tommaso Lenzi, Francesco Mazzeo, Pietro Luchetti, Silvia Casale, Fernanda Pacella   +8 more
doaj   +1 more source

Microenvironment‐Responsive Drug Delivery Systems for Ocular Surface Diseases: Mechanisms, Applications, and Translational Challenges

Small Science, Volume 6, Issue 8, August 2026.
Microenvironment‐responsive drug delivery systems overcome ocular physiological barriers by responding to temperature, pH, ions, reactive oxygen species, and enzymes. This review bridges material design, performance evaluation, and clinical translation, offering actionable insights for treating dry eye disease, infectious keratitis, and corneal ...
Jiamin Liu, Liangbo Chen, Yao Fu, Siyi Zhang   +3 more
wiley   +1 more source

Prognostic Factors for Postoperative Complications. An Aggregate Protocol for 10 Observational Studies From the Danish TRIPLE‐A Cohort of 1.2 Million Surgeries

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background Postoperative complications substantially increase morbidity, mortality and healthcare costs. Understanding prognostic factors is essential for risk stratification, targeted prevention strategies, and development of prediction models.
Anders Peder Højer Karlsen, Asta Prescott, Caroline Folkersen, Jens Laigaard, Atena Saito, Caroline Lando Klammer, Mik Wetterslev, Emil Ipsen Ørskov, Mathilde Fahrendorff, Rebecca Kiær, Helene Holm Laigaard, Nichlas Hovmand, Lars Hyldborg Lundstrøm, Sebastian Buhl Rasmussen, Anders Kehlet Nørskov, Markus Harboe Olsen   +15 more
wiley   +1 more source

Clinical and functional evaluation of efficiency in the treatment of macular edema associated with thrombosis of the central retinal vein and its branches

Офтальмохирургия, 2019
Purpose. An assessment of the efficacy of a prolonged corticosteroid and anti-VEGF therapy in the treatment of macular edema with thrombosis of the central retinal vein and its branches.Material and methods.
T. G. Kamenskikh, Y. S. Batishcheva, E. V. Gileva, I. O. Kolbenev   +3 more
doaj   +1 more source

Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng, Rongtai Su, Manyu Zhao, Xin Song, Ran Liu, Yuhao Zhou, Chaojuan Yang, Yanli Jiao, Xiao‐Wei Xiang, Lingqian Chang   +9 more
wiley   +1 more source

Hyperreflective foci (HRFs): A novel biomarker for intraocular inflammation (IOI) following intravitreal Brolucizumab

Indian Journal of Ophthalmology. Case Reports, 2023
Intraocular inflammation (IOI) has been reported after intravitreal brolucizumab injection. We report one such case of IOI successfully managed with intravitreal dexamethasone implant and hyperreflective foci (HRFs) as a novel OCT biomarker for IOI after
Vasumathy Vedantham, Chockalingam Nandini, Ratnagiri Praveen Krishna   +2 more
doaj   +1 more source