Results 51 to 60 of about 51,358 (247)

Emergency Palliative Cancer Care: Dexmedetomidine Treatment Experiences—A Retrospective Brief Report on Nine Consecutive Cases

Pain and Therapy, 2023
Introduction Dexmedetomidine, an alpha-2 adrenergic receptor agonist with potential opioid sparing properties, is utilized in palliative medicine, but the knowledge base for this practice is limited.
Erik Torbjørn Løhre, Augstein Svedahl, Gunnhild Jakobsen, Tora Skeidsvoll Solheim, Pål Klepstad, Morten Thronæs   +5 more
doaj   +1 more source

Is there a place for dexmedetomidine in equine anaesthesia and analgesia? : a systematic review (2005-2017) [PDF]

, 2018
The objective of this review was to perform a literature compilation of all the equine publications that used dexmedetomidine as the first article on this topic was published, in 2005.
Ambrisko, Ansah, Benmansour, Benmansour, Benmansour, Bettschart-Wolfensberger, Bettschart-Wolfensberger, Bettschart-Wolfensberger, Bettschart-Wolfensberger, De Clercq, Devisscher, Duke-Novakovski, Enderle, Gozalo-Marcilla, Gozalo-Marcilla, Gozalo-Marcilla, Gozalo-Marcilla, Gozalo-Marcilla, Grimsrud, Grimsrud, Grimsrud, Guedes, Hopster, Johnston, Kalchofner, Kharasch, Knych, Kuusela, Lizarraga, Lizarraga, Marcilla, Marcilla, Marly-Voquer, Müller, Pöppel, Ranheim, Rezende, Risberg, Risberg, Sacks, Santos, Savola, Schauvliege, Segal, Taylor, Wojtasiak-Wypart   +45 more
core   +2 more sources

Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss

Advanced Science, EarlyView.
 . ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao, Xiang Li, Yaqi Liao, Liman Liu, Xian Gao, Hailiang Lin, Wenli Ni, Huawei Li, Yan Chen, Wenyan Li   +9 more
wiley   +1 more source

The Current Role of Dexmedetomidine as Neuroprotective Agent: An Updated Review

Brain Sciences, 2021
Dexmedetomidine, selective α2-adrenergic agonist dexmedetomidine, has been widely used clinically for sedation and anesthesia. The role of dexmedetomidine has been an interesting topic of neonatological and anesthetic research since a series of ...
Zaara Liaquat, Xiaoying Xu, Prince Last Mudenda Zilundu, Rao Fu, Lihua Zhou   +4 more
doaj   +1 more source

Symptomatic treatment of children with anti-NMDAR encephalitis. [PDF]

, 2016
AIM: We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis.
Brilot, F, Dale, R. C., Hong, M, Jones, H, Mohammad, Ss, Nosadini, M, Pillai, Sc, Sharpe, C   +7 more
core   +1 more source

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source

EEG response of dexmedetomidine during drug induced sleep endoscopy

Frontiers in Neuroscience, 2023
IntroductionDexmedetomidine is one of the anesthetics of choice for drug induced sleep endoscopy (DISE), with advantages including limited respiratory depression, analgesia, and decreased incidence of emergence delirium.
Lichy Han, David R. Drover, Marianne C. Chen, Amit R. Saxena, Sarah L. Eagleman, Vladimir Nekhendzy, Angelica Pritchard, Robson Capasso   +7 more
doaj   +1 more source

Sentience in cephalopod molluscs: an updated assessment

Biological Reviews, EarlyView.
ABSTRACT This article evaluates the evidence for sentience – the capacity to have feelings – in cephalopod molluscs: octopus, cuttlefish, squid, and nautilus. Our framework includes eight criteria, covering both whether the animal's nervous system could support sentience and whether their behaviour indicates sentience.
Alexandra K. Schnell, Heather Browning, Andrew Crump, Charlotte C. Burn, Jonathan Birch   +4 more
wiley   +1 more source

Perbandingan Pemberian Dexmedetomidine dengan Fentanyl Intraoperatif terhadap Kedalaman Anestesia dan Kecepatan Pemulihan pada Operasi Bedah Saraf

Jurnal Neuroanestesi Indonesia, 2022
Latar Belakang dan Tujuan: Anestesi bebas opioid merupakan diskusi baru dalam dunia anestesi. Bukti menunjukkan bahwa opioid memiliki efek samping yang tidak diinginkan. Dexmedetomidine merupakan suatu reseptor agonis a2-adrenergik selektif yang memiliki
Zafrullah Kany Jasa, Teuku Heriansyah, Muttaqin Muttaqin   +2 more
doaj   +1 more source

Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial [PDF]

, 2010
Introduction Benzodiazepines and α2 adrenoceptor agonists exert opposing effects on innate immunity and mortality in animal models of infection. We hypothesized that sedation with dexmedetomidine (an α2 adrenoceptor agonist), as compared with lorazepam ...
Pratik P Pandharipande, Robert D Sanders, Timothy D Girard, Stuart McGrane, Jennifer L Thompson, Ayumi K Shintani, Daniel L Herr, Mervyn Maze, E Wesley Ely, The MENDS Investigators   +9 more
core   +2 more sources