Results 31 to 40 of about 40,767 (276)

Comparison of Dexmedetomidine-Nalbuphine combination Vs Dexmedetomidine alone on Clinical, Behavioral and Biochemical Investigations in Goat received TIVA via Ketofol. [PDF]

Benha Veterinary Medical Journal
The quality of sedation and analgesia on behavioral, cardio-pulmonary and biochemical effects of a novel pre-anesthetic medication consists of dexmedetomidine -nalbuphine combination were evaluated Vs dexmedetomidine alone within bucks undergoing a TIVA ...
Fatma Abdel-Al, Samy Farghaly Ismaeel, Ahmed Sabek, Ibrahim M. Abdel-Wadoud, Mohammed Ramadan, Ahmed Khalil   +5 more
doaj   +1 more source

Incidence of acute kidney injury after noncardiac surgery in patients receiving intraoperative dexmedetomidine: a retrospective study

BJA Open, 2023
Background: Postoperative acute kidney injury (AKI) is a common complication and is associated with increased hospital length of stay and 30 day all-cause mortality.
Manuel A. Paredes-Flores, Javier D. Lasala, Teresa Moon, Shreyas Bhavsar, Katherine Hagan, Sarah Huepenbecker, Nicolas P. Carram, Maria F. Ramirez, Kamal Maheswari, Lei Feng, Juan P. Cata   +10 more
doaj   +1 more source

Enantiospecific pharmacokinetics of intravenous dexmedetomidine in beagles. [PDF]

, 2022
The goal of this study was to investigate the pharmacokinetic (PK) behaviour of dexmedetomidine in dogs administered as a pure enantiomer versus as part of a racemic mixture. Eight unmedicated intact purpose-bread beagles were included.
Spadavecchia, Claudia, Olivier Louis Levionnois, Guidi, M., Raillard, M., Forss Pleyers, Tekla, Mathieu Raillard, Levionnois, O.L., Anisa Bardhi, Levionnois, Olivier Louis, Forss Pleyers, T., Guidi, Monia, Joelle Siegenthaler, Spadavecchia, C., Barbarossa, A., Bardhi, A., Bardhi, Anisa, Raillard, Mathieu, Claudia Spadavecchia, Tekla Forss Pleyers, Barbarossa, Andrea, Siegenthaler, Joelle, Andrea Barbarossa, Siegenthaler, J., Monia Guidi, Siegenthaler J., Forss Pleyers T., Guidi M., Bardhi A., Barbarossa A., Raillard M., Levionnois O. L., Spadavecchia C.   +31 more
core   +2 more sources

Comparison of a loading dose of dexmedetomidine combined with propofol or sevoflurane for hemodynamic changes during anesthesia maintenance: a prospective, randomized, double-blind, controlled clinical trial

BMC Anesthesiology, 2018
Background There may be great individual variability in the hemodynamic effects of this dexmedetomidine. For this reason, the dose must be carefully adjusted to achieve the desired clinical effect.
Yuan Han, Liu Han, Mengmeng Dong, Qingchun Sun, Ke Ding, Zhenfeng Zhang, Junli Cao, Yueying Zhang   +7 more
doaj   +1 more source

Safe electrophysiologic profile of dexmedetomidine in different experimental arrhythmia models

Scientific Reports, 2021
Previous studies suggest an impact of dexmedetomidine on cardiac electrophysiology. However, experimental data is sparse. Therefore, purpose of this study was to investigate the influence of dexmedetomidine on different experimental models of ...
Christian Ellermann, Jonas Brandt, Julian Wolfes, Kevin Willy, Felix K. Wegner, Patrick Leitz, Philipp S. Lange, Florian Reinke, Lars Eckardt, Gerrit Frommeyer   +9 more
doaj   +1 more source

The antioxidant effect of preischemic dexmedetomidine in a rat model: increased expression of Nrf2/HO-1 via the PKC pathway

Brazilian Journal of Anesthesiology, 2023
Background: The precise underlying mechanism of antioxidant effects of dexmedetomidine-induced neuroprotection against cerebral ischemia has not yet been fully elucidated.
Yong-Hee Park, Hee-Pyoung Park, Eugene Kim, Hannah Lee, Jung-Won Hwang, Young-Tae Jeon, Young-Jin Lim   +6 more
doaj   +1 more source

Dexmedetomidine vs Propofol as an Adjunct to Ketamine for Electroconvulsive Therapy Anaesthesia

, 2022
OBJECTIVE: Electroconvulsive therapy is an effective non-pharmacological treatment for refractory mental illness, where a generalized seizure is induced under general anaesthesia.
Türeci, Ercan, Yeter, Tuğçe, Tuğçe Yeter, Onur Gönen, Aybike, Aybike Onur Gönen, Ercan Türeci   +5 more
core   +1 more source

Dexmedetomidine-induced contraction of isolated rat aorta is dependent on extracellular calcium concentration [PDF]

Korean Journal of Anesthesiology, 2012
BackgroundDexmedetomidine is a highly selective α2-adrenoceptor agonist that is widely used for sedation and analgesia during the perioperative period. Intravenous administration of dexmedetomidine induces transient hypertension due to vasoconstriction ...
Seong-Ho Ok, Sung Il Bae, Haeng Seon Shim, Ju-Tae Sohn   +3 more
doaj   +1 more source

The Effect of Dexmedetomidine on Postoperative Nausea and Vomiting in Patients Undergoing Thoracic Surgery-A Meta-Analysis of a Randomized Controlled Trial

Frontiers in Surgery, 2022
BackgroundDexmedetomidine reduces the occurrence of postoperative nausea and vomiting (PONV); however, the effect of dexmedetomidine on PONV in patients undergoing thoracic surgery remains inconclusive.
Wei Zhang, Ruohan Wang, Bing Li, Ying Zhao, Xinmin Liu, Jingli Yuan   +5 more
doaj   +1 more source

Direct protective effects of dexmedetomidine against myocardial ischemia-reperfusion injury in anesthetized pigs [PDF]

, 2012
Systemic administration of α2-adrenergic agonists has been shown to protect ischemic myocardium, but the direct effects on ischemia-reperfused myocardium have not yet been clarified.
Cho, Sungsam, Maekawa, Takuji, Yoshitomi, Osamu, Hara, Tetsuya, Sumikawa, Koji, Shibata, Itsuko, Ureshino, Hiroyuki   +6 more
core   +1 more source