Results 21 to 30 of about 35,390 (262)

Comparison of Dexmedetomidine-Nalbuphine combination Vs Dexmedetomidine alone on Clinical, Behavioral and Biochemical Investigations in Goat received TIVA via Ketofol. [PDF]

open access: yesBenha Veterinary Medical Journal
The quality of sedation and analgesia on behavioral, cardio-pulmonary and biochemical effects of a novel pre-anesthetic medication consists of dexmedetomidine -nalbuphine combination were evaluated Vs dexmedetomidine alone within bucks undergoing a TIVA ...
Fatma Abdel-Al   +5 more
doaj   +1 more source

Comparison of a loading dose of dexmedetomidine combined with propofol or sevoflurane for hemodynamic changes during anesthesia maintenance: a prospective, randomized, double-blind, controlled clinical trial

open access: yesBMC Anesthesiology, 2018
Background There may be great individual variability in the hemodynamic effects of this dexmedetomidine. For this reason, the dose must be carefully adjusted to achieve the desired clinical effect.
Yuan Han   +7 more
doaj   +1 more source

Dexmedetomidine-induced contraction of isolated rat aorta is dependent on extracellular calcium concentration [PDF]

open access: yesKorean Journal of Anesthesiology, 2012
BackgroundDexmedetomidine is a highly selective α2-adrenoceptor agonist that is widely used for sedation and analgesia during the perioperative period. Intravenous administration of dexmedetomidine induces transient hypertension due to vasoconstriction ...
Seong-Ho Ok   +3 more
doaj   +1 more source

Direct protective effects of dexmedetomidine against myocardial ischemia-reperfusion injury in anesthetized pigs [PDF]

open access: yes, 2012
Systemic administration of α2-adrenergic agonists has been shown to protect ischemic myocardium, but the direct effects on ischemia-reperfused myocardium have not yet been clarified.
Cho, Sungsam   +6 more
core   +1 more source

Clinically relevant concentrations of dexmedetomidine may reduce oxytocin-induced myometrium contractions in pregnant rats [PDF]

open access: yesAnesthesia and Pain Medicine, 2020
Background Recently, there have been some trials to use dexmedetomidine in the obstetric field but concerns regarding the drug include changes in uterine contractions after labor.
Dong Joon Kim   +5 more
doaj   +1 more source

Comparative Study of Prilocaine-Dexmedetomidine versus Bupivacaine-Dexmedetomidine in Spinal Anaesthesia for Inguinal Hernia Repair Operation [PDF]

open access: yesAl-Azhar International Medical Journal, 2023
Background; fast track surgery necessitates the use of short-acting anaesthetics with minimum adverse effects. The purpose of this study is to assess the onset, offset time, and duration of motor and sensory block after spinal anaesthesia with hyperbaric
Fetouh Amr   +2 more
doaj   +1 more source

Real-time evaluation of the independent analgesic efficacy of dexmedetomidine

open access: yesBMC Anesthesiology, 2023
Background Dexmedetomidine has analgesic properties, but the intraoperative analgesic effect of dexmedetomidine is often masked by the effects of other general anaesthetics.
XiaoHua Wang   +6 more
doaj   +1 more source

The antioxidant effect of preischemic dexmedetomidine in a rat model: increased expression of Nrf2/HO-1 via the PKC pathway

open access: yesBrazilian Journal of Anesthesiology, 2023
Background: The precise underlying mechanism of antioxidant effects of dexmedetomidine-induced neuroprotection against cerebral ischemia has not yet been fully elucidated.
Yong-Hee Park   +6 more
doaj   +1 more source

In Vitro Effect of Dexmedetomidine on Platelet Aggregation

open access: yesBrazilian Journal of Anesthesiology, 2013
Background and objectives: : Dexmedetomidine is a selective α2-agonist. There are 250-300 α2- adrenoceptor on the surface of each human platelet and ephedrine induces platelet aggregation by binding these receptors.
Emine Arzu Kose   +3 more
doaj   +1 more source

Effect of sedation with dexmedetomidine or propofol on gastrointestinal motility in lipopolysaccharide-induced endotoxemic mice

open access: yesBMC Anesthesiology, 2020
Background Sepsis often accompanies gastrointestinal motility disorder that contributes to the development of sepsis in turn. Propofol and dexmedetomidine, as widely used sedatives in patients with sepsis, are likely to depress gastrointestinal ...
Haiqing Chang   +9 more
doaj   +1 more source

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