Results 21 to 30 of about 51,358 (247)
Real-time evaluation of the independent analgesic efficacy of dexmedetomidine
BMC Anesthesiology, 2023 Background Dexmedetomidine has analgesic properties, but the intraoperative analgesic effect of dexmedetomidine is often masked by the effects of other general anaesthetics.
XiaoHua Wang +6 more
doaj +1 more source
Pharmacokinetics, absolute bioavailability and tolerability of ketamine after intranasal administration to dexmedetomidine sedated dogs [PDF]
, 2020 Intranasal ketamine has recently gained interest in human medicine, not only for its sedative, anaesthetic or analgesic properties, but also in the management of treatment resistant depression, where it has been shown to be an effective, fast acting ...
Croubels, Siska +6 more
core +1 more source
In Vitro Effect of Dexmedetomidine on Platelet Aggregation
Brazilian Journal of Anesthesiology, 2013 Background and objectives: : Dexmedetomidine is a selective α2-agonist. There are 250-300 α2- adrenoceptor on the surface of each human platelet and ephedrine induces platelet aggregation by binding these receptors.
Emine Arzu Kose +3 more
doaj +1 more source
BMC Anesthesiology, 2020 Background Sepsis often accompanies gastrointestinal motility disorder that contributes to the development of sepsis in turn. Propofol and dexmedetomidine, as widely used sedatives in patients with sepsis, are likely to depress gastrointestinal ...
Haiqing Chang +9 more
doaj +1 more source
Brazilian Journal of Anesthesiology, 2023 Background: The precise underlying mechanism of antioxidant effects of dexmedetomidine-induced neuroprotection against cerebral ischemia has not yet been fully elucidated.
Yong-Hee Park +6 more
doaj +1 more source
Review of the effects of anesthetic agents used as premedication for patients undergoing electroconvulsive therapy with diagnoses of bipolar disorder or major depression on convulsion, recovery period, and hemodynamic parameters [PDF]
, 2019 Objective: The aim of this study was to examine the effects of anesthetic agents used as premedication in patients undergoing electroconvulsive therapy (ECT) for diagnoses of bipolar disorder or major depression in terms of convulsion, recovery period ...
Orhan, Mehmet Emin, Ozen, Volkan
core +2 more sources
Relationship between dexmedetomidine dose and plasma dexmedetomidine concentration in critically ill infants: a prospective observational cohort study [PDF]
Korean Journal of Anesthesiology, 2017 BackgroundDexmedetomidine is a highly selective central α2-agonist used as a sedative in pediatric intensive care unit (PICU). However, little is known about the relationship between dexmedetomidine dose and its plasma concentration during long-term ...
Yoshihito Fujita +6 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Background and Purpose: There are many benefits of administering dexmedetomidine perioperatively. The pharmacokinetics (PK) and pharmacodynamics (PD) of intravenous, intranasal and oral dexmedetomidine that was administered before anesthesia were ...
Jinhong Wu +5 more
doaj +1 more source
Risk Factors of Intraoperative Dysglycemia in Elderly Surgical Patients [PDF]
, 2019 BACKGROUNDː Dysglycemia is associated with adverse outcome including increased morbidity and mortality in surgical patients. Acute insulin resistance due to the surgical stress response is seen as a major cause of so-called stress hyperglycemia. However,
Knaak, Cornelia +8 more
core +1 more source
Patient Safety in Surgery, 2020 Background Dexmedetomidine, an α2 agonist, has well-known anesthetic and analgesic-sparing effects. We designed this study to evaluate the effect of intraoperative dexmedetomidine infusion on intra operative blood loss and postoperative pain in ...
Mohammad Reza Fazel +3 more
doaj +1 more source