Comparison of Dexmedetomidine-Nalbuphine combination Vs Dexmedetomidine alone on Clinical, Behavioral and Biochemical Investigations in Goat received TIVA via Ketofol. [PDF]
The quality of sedation and analgesia on behavioral, cardio-pulmonary and biochemical effects of a novel pre-anesthetic medication consists of dexmedetomidine -nalbuphine combination were evaluated Vs dexmedetomidine alone within bucks undergoing a TIVA ...
Fatma Abdel-Al +5 more
doaj +1 more source
Background There may be great individual variability in the hemodynamic effects of this dexmedetomidine. For this reason, the dose must be carefully adjusted to achieve the desired clinical effect.
Yuan Han +7 more
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Dexmedetomidine-induced contraction of isolated rat aorta is dependent on extracellular calcium concentration [PDF]
BackgroundDexmedetomidine is a highly selective α2-adrenoceptor agonist that is widely used for sedation and analgesia during the perioperative period. Intravenous administration of dexmedetomidine induces transient hypertension due to vasoconstriction ...
Seong-Ho Ok +3 more
doaj +1 more source
Direct protective effects of dexmedetomidine against myocardial ischemia-reperfusion injury in anesthetized pigs [PDF]
Systemic administration of α2-adrenergic agonists has been shown to protect ischemic myocardium, but the direct effects on ischemia-reperfused myocardium have not yet been clarified.
Cho, Sungsam +6 more
core +1 more source
Clinically relevant concentrations of dexmedetomidine may reduce oxytocin-induced myometrium contractions in pregnant rats [PDF]
Background Recently, there have been some trials to use dexmedetomidine in the obstetric field but concerns regarding the drug include changes in uterine contractions after labor.
Dong Joon Kim +5 more
doaj +1 more source
Comparative Study of Prilocaine-Dexmedetomidine versus Bupivacaine-Dexmedetomidine in Spinal Anaesthesia for Inguinal Hernia Repair Operation [PDF]
Background; fast track surgery necessitates the use of short-acting anaesthetics with minimum adverse effects. The purpose of this study is to assess the onset, offset time, and duration of motor and sensory block after spinal anaesthesia with hyperbaric
Fetouh Amr +2 more
doaj +1 more source
Real-time evaluation of the independent analgesic efficacy of dexmedetomidine
Background Dexmedetomidine has analgesic properties, but the intraoperative analgesic effect of dexmedetomidine is often masked by the effects of other general anaesthetics.
XiaoHua Wang +6 more
doaj +1 more source
Background: The precise underlying mechanism of antioxidant effects of dexmedetomidine-induced neuroprotection against cerebral ischemia has not yet been fully elucidated.
Yong-Hee Park +6 more
doaj +1 more source
In Vitro Effect of Dexmedetomidine on Platelet Aggregation
Background and objectives: : Dexmedetomidine is a selective α2-agonist. There are 250-300 α2- adrenoceptor on the surface of each human platelet and ephedrine induces platelet aggregation by binding these receptors.
Emine Arzu Kose +3 more
doaj +1 more source
Background Sepsis often accompanies gastrointestinal motility disorder that contributes to the development of sepsis in turn. Propofol and dexmedetomidine, as widely used sedatives in patients with sepsis, are likely to depress gastrointestinal ...
Haiqing Chang +9 more
doaj +1 more source

