Results 11 to 20 of about 28,483 (230)
Journal of International Medical Research, 2022 Objective We investigated the effect of dexmedetomidine anesthesia on postoperative cognitive function after pulmonary surgery. Methods A blinded, prospective, randomized, placebo-controlled study was performed on 60 patients (age range 65–74 years ...
Tao Liu +9 more
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Effect of dexmedetomidine on cardiorespiratory regulation in spontaneously breathing adult rats.
PLoS ONE, 2022 PurposeWe examined the cardiorespiratory effect of dexmedetomidine, an α2- adrenoceptor/imidazoline 1 (I1) receptor agonist, in spontaneously breathing adult rats.MethodsMale rats (226-301 g, n = 49) under isoflurane anesthesia had their tail vein ...
Yoichiro Kitajima +4 more
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Comparison of Dexmedetomidine-Nalbuphine combination Vs Dexmedetomidine alone on Clinical, Behavioral and Biochemical Investigations in Goat received TIVA via Ketofol. [PDF]
Benha Veterinary Medical JournalThe quality of sedation and analgesia on behavioral, cardio-pulmonary and biochemical effects of a novel pre-anesthetic medication consists of dexmedetomidine -nalbuphine combination were evaluated Vs dexmedetomidine alone within bucks undergoing a TIVA ...
Fatma Abdel-Al +5 more
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Brazilian Journal of Anesthesiology, 2023 Background: The precise underlying mechanism of antioxidant effects of dexmedetomidine-induced neuroprotection against cerebral ischemia has not yet been fully elucidated.
Yong-Hee Park +6 more
doaj +1 more source
Safe electrophysiologic profile of dexmedetomidine in different experimental arrhythmia models
Scientific Reports, 2021 Previous studies suggest an impact of dexmedetomidine on cardiac electrophysiology. However, experimental data is sparse. Therefore, purpose of this study was to investigate the influence of dexmedetomidine on different experimental models of ...
Christian Ellermann +9 more
doaj +1 more source
BJA Open, 2023 Background: Postoperative acute kidney injury (AKI) is a common complication and is associated with increased hospital length of stay and 30 day all-cause mortality.
Manuel A. Paredes-Flores +10 more
doaj +1 more source
BMC Anesthesiology, 2018 Background There may be great individual variability in the hemodynamic effects of this dexmedetomidine. For this reason, the dose must be carefully adjusted to achieve the desired clinical effect.
Yuan Han +7 more
doaj +1 more source
Dexmedetomidine-induced contraction of isolated rat aorta is dependent on extracellular calcium concentration [PDF]
Korean Journal of Anesthesiology, 2012 BackgroundDexmedetomidine is a highly selective α2-adrenoceptor agonist that is widely used for sedation and analgesia during the perioperative period. Intravenous administration of dexmedetomidine induces transient hypertension due to vasoconstriction ...
Seong-Ho Ok +3 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Background and Purpose: There are many benefits of administering dexmedetomidine perioperatively. The pharmacokinetics (PK) and pharmacodynamics (PD) of intravenous, intranasal and oral dexmedetomidine that was administered before anesthesia were ...
Jinhong Wu +5 more
doaj +1 more source
Frontiers in Surgery, 2022 BackgroundDexmedetomidine reduces the occurrence of postoperative nausea and vomiting (PONV); however, the effect of dexmedetomidine on PONV in patients undergoing thoracic surgery remains inconclusive.
Wei Zhang +5 more
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