Results 141 to 150 of about 163,143 (320)

Construction of a Biomimetic Tubular Scaffold Inspired by Sea Sponge Structure: Sponge‐Like Framework and Cell Guidance

open access: yesAdvanced Science, EarlyView.
Inspired by the structure of sea sponges, a unique method involving microfluidic coaxial spinning and in situ polymerization is designed. Biomimetic tubular scaffolds ae fabricated. Composed of specific materials such as oxidized bacterial cellulose, bacterial cellulose and polydopamine, these scaffolds have excellent mechanical stability and ...
Si Meng   +10 more
wiley   +1 more source

Annexin A3 Represses Endothelial Permeability and Inflammation During Sepsis via Actin Cytoskeleton Modulation

open access: yesAdvanced Science, EarlyView.
Annexin A3 (ANXA3) plays an endogenous protective role in endothelial dysfunction in sepsis by stabilizing the actin cytoskeleton, modulating cell permeability, and inhibiting pATF2/CD62E inflammatory signaling. Abstract Increased endothelial permeability and a dysregulated inflammatory response play key roles in organ damage in sepsis.
Manyu Xing   +4 more
wiley   +1 more source

The phospholipid flippase ATP8B1 is required for lysosomal fusion in macrophages

open access: yesCell Biochemistry and Function, Volume 40, Issue 8, Page 914-925, December 2022., 2022
Abstract ATP8B1 is a phospholipid flippase and member of the type 4 subfamily of P‐type ATPases (P4‐ATPase) subfamily. P4‐ATPases catalyze the translocation of phospholipids across biological membranes, ensuring proper membrane asymmetry, which is crucial for membrane protein targeting and activity, vesicle biogenesis, and barrier function.
Valentina E. Gómez‐Mellado   +7 more
wiley   +1 more source

Longitudinal, Multimodal Tracking Reveals Lasting Neurovascular Impact of Individual Microinfarcts

open access: yesAdvanced Science, EarlyView.
Jin et al. investigate the neurovascular impact of microinfarcts, revealing transient neural suppression with minimal cell death and recovery linked to vascular remodeling. Fast‐spiking interneurons exhibit reduced excitability, whereas regular‐spiking neurons showed increased bursting activity. Disruptions in low‐gamma phase locking suggest persistent
Yifu Jin   +9 more
wiley   +1 more source

Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics

open access: yesAdvanced Science, EarlyView.
Intestinal barrier stability is vital for gut health. Plastic polyethylene terephthalate (PET) disrupts this barrier, causing inflammation and infections. This study encodes transforming growth factor‐β into EcN and modifies its surface with pH‐responsive polymer (EcNT@L), creating an oral drug delivery system to repair nano PET‐induced intestinal ...
Wenxin Chen   +9 more
wiley   +1 more source

Aqueous Two‐Phase Submicron Droplets Catalyze DNA Nanostructure Assembly for Confined Fluorescent Biosensing

open access: yesAdvanced Science, EarlyView.
Submicron droplets, formed by a polyethyleneglycol (PEG)/dextran aqueous two‐phase system·(ATPS), can act as catalytic centers that concentrate DNA and accelerate assembly kinetic in crowded environments. It highlights a cooperative mechanism wherein global crowding from PEG induces an excluded volume effect, while local crowding from dextran provides ...
Xiaoman Duan   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy