Results 41 to 50 of about 163,143 (320)
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim+3 more
wiley +1 more source
Coacervation driven by liquid‐liquid phase separation (LLPS) of biopolymers has garnered increasing attention in biology since this leads to the formation of membraneless organelles capable of performing essential yet largely unknown functions. This review highlights recent advances in coacervates (artificial condensates) composed of low‐molecular ...
Sayuri L. Higashi, Masato Ikeda
wiley +1 more source
Remineralization of Dentin with Cerium Oxide and Its Potential Use for Root Canal Disinfection
Yinlin Wang,1 Xinyue Zhang,2 Haiyan Zheng,1 Zihuai Zhou,1 Si Li,1 Jimin Jiang,1 Mingxing Li,1 Baiping Fu1 1Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang ...
Wang Y+7 more
doaj
Regulating Protein Immobilization During Cell‐Free Protein Synthesis in Hyaluronan Microgels
Bifunctional microgels carrying a linear DNA template and Ni2+‐activated NTA moieties are used as platform for cell‐free protein synthesis and in situ protein immobilization. By varying the concentration of NTA moieties in the microgels, the amount of GFP‐His immobilized inside the microgel and released to the microgel environment can be regulated ...
Anika Kaufmann+2 more
wiley +1 more source
Important factors for cell-membrane permeabilization by gold nanoparticles activated by nanosecond-laser irradiation [PDF]
Purpose: Pulsed-laser irradiation of light-absorbing gold nanoparticles (AuNPs) attached to cells transiently increases cell membrane permeability for targeted molecule delivery. Here, we targeted EGFR on the ovarian carcinoma cell line OVCAR-3 with AuNPs.
arxiv +1 more source
Maleimidation of dextran and the application in designing a dextran–camptothecin conjugate
In this study, we developed the maleimidiation of dextran and applied it in a camptothecin drug delivery system.
Qiwen Zhu+4 more
openaire +4 more sources
Dextran and Insulin in Rats [PDF]
WHILE testing the effects of insulin on the circulatory reaction of laboratory rats to dextran, we found that many animals died after combined doses of the two agents which were not lethal when administered separately. The validity of this observation was put to experimental test. Male Sprague-Dawley rats weighing at least 150 gm.
C H Hanna, L. H. Marshall
openaire +3 more sources
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng+12 more
wiley +1 more source
Isotropic-nematic phase transition in suspensions of filamentous virus and the neutral polymer Dextran [PDF]
We present an experimental study of the isotropic-nematic phase transition in an aqueous mixture of charged semi-flexible rods (fd virus) and neutral polymer (Dextran). A complete phase diagram is measured as a function of ionic strength and polymer molecular weight.
arxiv +1 more source
Cooperative rheological state-switching of enzymatically-driven composites of circular DNA and dextran [PDF]
Polymer topology, which plays a principal role in the rheology of polymeric fluids, and non-equilibrium materials, which exhibit time-varying rheological properties, are topics of intense investigation. Here, we push composites of circular DNA and dextran out-of-equilibrium via enzymatic digestion of DNA rings to linear fragments.
arxiv