Results 21 to 30 of about 125,338 (250)

Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth

open access: yesNature Communications, 2017
Βeta-cells have recently been shown to be heterogeneous with regard to morphology and function. Here, the authors show that β-cells in zebrafish switch from proliferative to functional states with increasing time since β-cell birth, leading to functional
Sumeet Pal Singh   +13 more
doaj   +1 more source

Foxp3+ Regulatory T Cells in Bone and Hematopoietic Homeostasis

open access: yesFrontiers in Endocrinology, 2019
The bone represents surprisingly dynamic structures that are subject to constant remodeling by the concerted action of bone-forming osteoblasts and bone-resorbing osteoclasts - two cell subsets of distinct developmental origin that are key in maintaining
Luise Fischer   +8 more
doaj   +1 more source

Cell Cycle Activity of Neurogenic and Oligodendrogenic Progenitors in the Diseased Mammalian Brain

open access: yesFrontiers in Neuroscience, 2014
Basic research during embryonic development has led to the identification of general principles governing cell cycle progression, proliferation and differentiation of mammalian neural stem cells (NSC). These findings were recently translated to the adult
Sara eBragado Alonso   +2 more
doaj   +1 more source

Characterization and Cell Viability of Probiotic/Prebiotics Film Based on Duck Feet Gelatin: A Novel Poultry Gelatin as a Suitable Matrix for Probiotics

open access: yesFoods, 2021
The probiotic viability, physicochemical, mechanical, barrier, and microstructure properties of synbiotic edible films (SEFs) based on duck feet gelatin (DFG) were evaluated. Four synbiotic systems were obtained by mixing four types of prebiotics, namely,
Ahmadreza Abedinia   +8 more
doaj   +1 more source

Generation of 8–20 μm Mid-Infrared Ultrashort Femtosecond Laser Pulses via Difference Frequency Generation

open access: yesPhotonics, 2022
Mid-infrared (MIR) ultrashort laser pulses have a wide range of applications in the fields of environmental monitoring, laser medicine, food quality control, strong-field physics, attosecond science, and some other aspects.
Xinyang Su   +8 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Distinct Levels of Reactive Oxygen Species Coordinate Metabolic Activity with Beta-cell Mass Plasticity

open access: yesScientific Reports, 2017
The pancreatic beta-cells control glucose homeostasis by secreting insulin in response to nutrient intake. The number of beta-cells is under tight metabolic control, as this number increases with higher nutrient intake.
Ezzaldin Ahmed Alfar   +5 more
doaj   +1 more source

Primary Spinal OPC Culture System from Adult Zebrafish to Study Oligodendrocyte Differentiation In Vitro

open access: yesFrontiers in Cellular Neuroscience, 2017
Endogenous oligodendrocyte progenitor cells (OPCs) are a promising target to improve functional recovery after spinal cord injury (SCI) by remyelinating denuded, and therefore vulnerable, axons.
Volker Kroehne   +10 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Digitalisierung der vollständigen deutschsprachigen Zeitungen des 17. Jahrhunderts in der SuUB Bremen: Ein Werkstattbericht

open access: yeso-bib. Das offene Bibliotheksjournal, 2014
Seit Mai 2013 fördert die Deutsche Forschungsgemeinschaft (DFG) Pilotprojekte zur Digitalisierung historischer Zeitungen in vier Bibliotheken Deutschlands, darunter in der Staats- und Universitätsbibliothek Bremen.
Maria Hermes, Maria Elisabeth Müller
doaj   +1 more source

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