Results 41 to 50 of about 125,059 (252)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Conserving Poverty: Destructive Fishing Gear Use in a Tanzanian Marine Protected Area
Conservation & Society, 2019 Drawing from ethnographic fieldwork, this paper attends to the persistent use of Destructive Fishing Gear (DFG) in a Marine Protected Area (MPA) in southeastern Tanzania.
Justin Raycraft
doaj +1 more source
International Journal of Food Properties, 2022 The core objective of this research work was to determine the nutritional and bioactive profile of raw and fermented (black) garlic. For this purpose, different varieties of garlic i.e., desi and farmi were procured from local market of Faisalabad ...
Zunaira Tahir +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Orbital Dermis-Fat Graft Transplantation: Results in Primary and Secondary Implantation
Türk Oftalmoloji Dergisi, 2015 Objectives: Autologous dermis fat graft (DFG) is being used in both primary and secondary socket surgeries. In the present study, we aimed to evaluate patients’ satisfaction and possible intra- and postoperative complications in patients who had DFG ...
Müge Çoban Karataş +2 more
doaj +1 more source
Difference-frequency generation in optically poled silicon nitride waveguides
Nanophotonics, 2021 Difference-frequency generation (DFG) is elemental for nonlinear parametric processes such as optical parametric oscillation and is instrumental for generating coherent light at long wavelengths, especially in the middle infrared.
Sahin Ezgi +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
An integrated photonic circuit for color qubit preparation by third-order nonlinear interactions
Scientific Reports, 2022 This work presents a feasible design of an integrated photonic circuit performing as a device for single-qubit preparation and rotations through the third-order nonlinear process of difference frequency generation (DFG) and defined in the temporal mode ...
A. L. Aguayo-Alvarado +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source