Results 231 to 240 of about 46,464 (291)
Some of the next articles are maybe not open access.
Photo-DHEA—A functional photoreactive dehydroepiandrosterone (DHEA) analog
Steroids, 2011The steroid hormone dehydroepiandrosterone (DHEA) has beneficial effects on vascular function, survival of neurons, and fatty acid metabolism. However, a specific receptor for DHEA has not been identified to date. Here, we describe the synthesis of a photoreactive DHEA derivative (Photo-DHEA).
Gustav, Waschatko +3 more
openaire +2 more sources
Clinical Journal of Sport Medicine, 2002
Dehydroepiandrosterone (DHEA), a 19-carbon steroid, is situated along the steroid metabolic pathway. It is the most abundant circulating hormone in the body and can be converted to either androgens or estrogens. It is readily conjugated to its sulphate ester DHEAS, and they are designated as DHEA(S) here when used together. Its secretion reaches a peak
openaire +2 more sources
Dehydroepiandrosterone (DHEA), a 19-carbon steroid, is situated along the steroid metabolic pathway. It is the most abundant circulating hormone in the body and can be converted to either androgens or estrogens. It is readily conjugated to its sulphate ester DHEAS, and they are designated as DHEA(S) here when used together. Its secretion reaches a peak
openaire +2 more sources
Lack of Hepatic Conversion of Dehydroepiandrosterone Sulfate (DHEAS) to DHEA
Endocrine Research, 2004DHEA and its sulfate ester DHEAS are the most abundant steroids in the human circulation. Only desulfated DHEA is biologically active and can be converted downstream toward sex steroids. The current concept is that DHEAS serves as the hydrophilic storage pool for DHEA regeneration and that DHEA and DHEAS are interconverted freely via hydroxysteroid ...
F, Hammer +6 more
openaire +2 more sources
Neuroactive neurosteroids: dehydroepiandrosterone (DHEA) and DHEA sulphate
Acta Paediatrica, 1999Dehydroepiandrosterone (DHEA) and its sulphate ester (DHEAS) are neuroactive and are both imported into the brain from the circulation and produced in the nervous system. These neurosteroids have neurotrophic and excitatiory effets, and further study is needed to delineate their physiological and pathological functions.
openaire +2 more sources
Dehydroepiandrosterone (DHEA) and aging
Archives of Gerontology and Geriatrics, 1997Dehydroepiandrosterone sulfate (DHEAS) is the most abundant circulating steroid hormone in humans and can readily be converted to its parent steroid DHEA by tissue sulfatases. Yet, a biologic function for these steroids has not been defined. The link between DHEA and aging has been raised by: (1) its well documented age-related decline, and (2) a ...
Z, Barrou, P, Charru, C, Lidy
openaire +2 more sources
Current Opinion in Obstetrics and Gynecology, 1996
Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) represent the major androgens secreted by the adrenal gland. Various functions including metabolic, immune, and cognitive effects have been attributed to this steroid and are reviewed here. Since the levels of DHEA correlate with general good health, and aging is associated with a decline in the ...
openaire +2 more sources
Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) represent the major androgens secreted by the adrenal gland. Various functions including metabolic, immune, and cognitive effects have been attributed to this steroid and are reviewed here. Since the levels of DHEA correlate with general good health, and aging is associated with a decline in the ...
openaire +2 more sources
Dehydroepiandrosterone (DHEA) and DHEA-Sulfate (DS) as Therapeutic Options in Menopause
Seminars in Reproductive Medicine, 1998In recent years, there has been increasing interest in the potential of androgen replacement in menopausal women and specifically adrenal androgen replacement. There is unfortunately increasing unmonitored use of dehydroepiandrosterone (DHEA) among adults in the United States with only limited and preliminary human data. An extensive body of literature
S, Katz, A J, Morales
openaire +2 more sources
Altered DHEA and DHEAS Response to Exercise in Healthy Older Adults
Journal of Aging and Physical Activity, 2009Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) are hormones produced by the adrenal cortex that decline in concentration with age. Decreased DHEA levels are associated with age-related disease and oxidative stress but might be increased in younger adults by exercise.
Sarah, Aldred +3 more
openaire +2 more sources
Annals of Pharmacotherapy, 2000
OBJECTIVE: To inform clinicians and investigators of the potential for severe mania in conjunction with the use of prasterone (DHEA; dehydroepiandrosterone). CASE SUMMARY: A 31-year-old Hispanic man was admitted on a 72-hour ...
openaire +2 more sources
OBJECTIVE: To inform clinicians and investigators of the potential for severe mania in conjunction with the use of prasterone (DHEA; dehydroepiandrosterone). CASE SUMMARY: A 31-year-old Hispanic man was admitted on a 72-hour ...
openaire +2 more sources
A review of dehydroepiandrosterone (DHEA)
Integrative Physiological and Behavioral Science, 1995Dehydroepiandrosterone (DHEA) is quantitatively the most abundant hormone in humans and mammals, with a wide variety of physiological effects, including major regulatory effects upon the immune system. Two of the most striking aspects of DHEA are a steady decline in DHEA with age and a significant deficiency in DHEA in patients with several major ...
openaire +2 more sources