Results 131 to 140 of about 39,011 (239)

Analysis of the mouse Dhfr/Rep-3 major promoter region by using linker-scanning and internal deletion mutations and DNase I footprinting. [PDF]

, 1990
Melvyn Smith, Pamela J. Mitchell, Gray F. Crouse   +2 more
openalex   +1 more source

Differential utilization of poly (A) signals between DHFR alleles in CHL cells [PDF]

, 1992
Kathleen W. Scotto, Honghao Yang, Joseph P. Davide, Peter W. Melera   +3 more
openalex   +1 more source

A genetic polymorphism within the third poly(A) signal of the DHFR gene alters the polyadenylation pattern of DHFR transcripts in CHL cells [PDF]

, 1994
Honghao Yang, Peter W. Melera
openalex   +1 more source

Design, synthesis, in vitro and in silico studies of novel piperidine derived thiosemicarbazones as inhibitors of dihydrofolate reductase

Scientific Reports
Dihydrofolate reductase (DHFR), an essential enzyme in folate metabolism, presents a promising target for drug development against various diseases, including cancer and tuberculosis.
Hina Aftab, Saeed Ullah, Ajmal Khan, Mariya al-Rashida, Talha Islam, Kholood A. Dahlous, Saikh Mohammad, Hamdy Kashtoh, Ahmed Al-Harrasi, Zahid Shafiq   +9 more
doaj   +1 more source

Extraction of ursolic acid from Ocimum sanctum and synthesis of its novel derivatives: effects on extracellular homocysteine, dihydrofolate reductase activity and proliferation of HepG2 human hepatoma cells

Pteridines, 2013
The objective of the present study was to extract ursolic acid (UA) from Ocimum sanctum, to synthesize its bioactive derivatives, evaluate the anti-cancer effect of its derivatives and to establish the possible mechanism of action. In the present report,
Batra Apsara, Sastry V. Girija
doaj   +1 more source

Virulent or avirulent (dhfr-ts−)Leishmania majorelicit predominantly a type-1 cytokine response by human cellsin vitro [PDF]

, 2000
Cláudia Brodskyn, Stephen M. Beverley, Richard G. Titus   +2 more
openalex   +1 more source

Dihydrofolate Reductase I164L Mutation in Plasmodium falciparum, Madagascar

Emerging Infectious Diseases, 2008
Didier Ménard, Valérie Andriantsoanirina, Martial Jahevitra, Céline Barnadas, Magali Tichit, Christiane Bouchier, Carol Hopkins Sibley   +6 more
doaj   +1 more source

The dhfr oribeta-binding protein RIP60 contains 15 zinc fingers: DNA binding and looping by the central three fingers and an associated proline-rich region [PDF]

, 2000
Christopher R. Houchens
openalex   +1 more source

DNA Repair of Benzo[A]Pyrene Diol Epoxide-DNA Adducts in the DHFR Gene of a Human Embryonic Kidney Cell Line [PDF]

, 2000
Laura Schild, Charles A. Smith, Philip C. Hanawalt, William M. Baird   +3 more
openalex   +1 more source

Plasmodium falciparum: pfcrtandDHFRMutations Are Associated with Failure of Chloroquine plus Proguanil Prophylaxis in Travelers [PDF]

, 2001
Rémy Durand, Sayeh Jafari, Olivier Bouchaud, Pascal Ralaimazava, A Keundjian, Jacques Le Bras   +5 more
openalex   +1 more source