Results 191 to 200 of about 40,426 (262)

Identification of potential inhibitors of dihydrofolate reductase (DHFR) through blocking the folate biosynthetic pathway of <i>Mycobacterium tuberculosis</i> utilizing structure-based virtual screening. [PDF]

RSC Adv
Halder SK, Sultana A, Ahmad I, Rafi MO, Sultana I, Elma F, Ananna IJ, Patel H, Himel MK, Shil A.   +9 more
europepmc   +1 more source

Hybrid Caffeic Acid-Based DHFR Inhibitors as Novel Antimicrobial and Anticancer Agents [PDF]

Renu Sehrawat, Ritu Pasrija, Priyanka Rathee, Deepika Kumari, Anurag Khatkar, Esra Küpeli Akkol, Eduardo Sobarzo‐Sánchez   +6 more
openalex   +1 more source

Investigation of 6-thioguanine as a strategy to overcome methotrexate resistance in a mouse model of leptomeningeal carcinomatosis. [PDF]

J Neurooncol
Nakagawa H, Yui Y, Suzuki T, Tamura M, Yamada M, Kawaichi M.   +5 more
europepmc   +1 more source

Chromothripsis and ecDNA initiated by N4BP2 nuclease fragmentation of cytoplasm-exposed chromosomes. [PDF]

Science
Krupina K, Goginashvili A, Baughn MW, Moore S, Steele CD, Nguyen AT, Zhang DL, Koeppel J, Trivedi P, Malhotra A, Jenkins D, Shiau AK, Miyake Y, Koga T, Miki S, Furnari FB, Campbell PJ, Alexandrov LB, Cleveland DW.   +18 more
europepmc   +1 more source

Multiple transcription start sites, DNase I-hypersensitive sites, and an opposite-strand exon in the 5' region of the CHO dhfr gene

Molecular and Cellular Biology, 1986
P. J. Mitchell, A. Carothers, J. Han, J. Harding, E. Kas, L. Venolia, L. Chasin   +6 more
semanticscholar   +1 more source

Loss of NcBPK1 impairs bradyzoite differentiation and enhances virulence in Neospora caninum. [PDF]

Parasit Vectors
Amieva R, Rico-San Román L, Pastor-Fernández I, Hemphill A, Boubaker G, Collantes-Fernández E, Ortega-Mora LM, Horcajo P.   +7 more
europepmc   +1 more source

Emergence of a dhfr mutation conferring high-level drug resistance in Plasmodium falciparum populations from southwest Uganda.

Journal of Infectious Diseases, 2008
C. Lynch, R. Pearce, Hirva Pota, J. Cox, T. Abeku, J. Rwakimari, I. Naidoo, J. Tibenderana, C. Roper   +8 more
semanticscholar   +1 more source

Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR)

, 2018
Valeria Francesconi, Luca Giovannini, Matteo Santucci, Elena Cichero, Maria Paola Costi, Lieve Naesens, Fabrizio Giordanetto, Michele Tonelli   +7 more
openalex   +2 more sources

Protozoan Neglected Tropical Diseases (NTDs) Target Inhibition of Alkaloids from <i>Croton linearis</i> Jacq Leaves: A Molecular Docking and ADMET Approach. [PDF]

Pharmaceuticals (Basel)
Rojas-Vargas JA, García-Díaz J, Escalona-Arranz JC, Chlebek J, Monzote L, Setzer WN, Castillo-Garit JA.   +6 more
europepmc   +1 more source

3C1124 Theoretical study of modulation of global fluctuation by local mutation in DHFR(3C Protein: Funcrion 2,The 49th Annual Meeting of the Biophysical Society of Japan)

, 2011
Daiki Kaita, Akinori Awazu, Hiraku Nishimori   +2 more
openalex   +2 more sources