Results 241 to 250 of about 40,426 (262)

Low prevalence of DHFR and DHPS mutations in Pneumocystis jirovecii strains obtained from a German cohort

Infection, 2017
I. Suárez, Lisa Roderus, Edeltraud van Gumpel, N. Jung, C. Lehmann, G. Fätkenheuer, P. Hartmann, G. Plum, J. Rybniker   +8 more
semanticscholar   +1 more source

Targeting feed-forward signaling of TGFβ/NOX4/DHFR/eNOS uncoupling/TGFβ axis with anti-TGFβ and folic acid attenuates formation of aortic aneurysms: Novel mechanisms and therapeutics

Redox Biology, 2021
Yixuan Zhang, Hua Cai
exaly  

Repositioning of DHFR Inhibitors.

Current Topics in Medicinal Chemistry, 2016
Arundhati C. Lele, Deepak Mishra, T. K. Kamil, S. Bhakta, M. Degani   +4 more
semanticscholar   +1 more source

Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

Cell, 1987
I. Mellon, G. Spivak, P. Hanawalt
semanticscholar   +1 more source

New thiazole-based derivatives as EGFR/HER2 and DHFR inhibitors: Synthesis, molecular modeling simulations and anticancer activity

European Journal of Medicinal Chemistry, 2022
Hussein I El-Subbagh
exaly  

DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall

Cell, 1985
V. Bohr, C. A. Smith, D. Okumoto, P. Hanawalt   +3 more
semanticscholar   +1 more source

Evaluation of UDP-glucuronosyltransferase 2B17 (UGT2B17) and dihydrofolate reductase (DHFR) genes deletion and the expression level of NGX6 mRNA in breast cancer

Molecular Biology Reports, 2012
E. Eskandari‐Nasab, M. Hashemi, H. Rezaei, A. Fazaeli, M. Mashhadi, Simin Sargholzaei Moghaddam, F. Arbabi, M. Jahantigh, M. Taheri   +8 more
semanticscholar   +1 more source

Synthesis, Biological Activity, and Molecular Dynamics Study of Novel Series of a Trimethoprim Analogs as Multi-Targeted Compounds: Dihydrofolate Reductase (DHFR) Inhibitors and DNA-Binding Agents

International Journal of Molecular Sciences, 2021
Agnieszka Wróbel, Artur Ratkiewicz, Danuta Drozdowska   +2 more
exaly  

Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity

Molecules, 2020
Ashraf Sayed Hassan, Ahmed A Askar, Ahmed M Naglah   +2 more
exaly  

Improved recombinant protein yield using a codon deoptimized DHFR selectable marker in a CHEF1 expression plasmid

Biotechnology progress (Print), 2010
Amy D. Westwood, Daniel A. Rowe, Howard R G Clarke   +2 more
semanticscholar   +1 more source