Results 251 to 260 of about 40,426 (262)

Probing the structure of Leishmania donovani chagasi DHFR-TS: comparative protein modeling and protein–ligand interaction studies

Journal of Molecular Modeling, 2010
Lakshmi Maganti, P. Manoharan, N. Ghoshal   +2 more
semanticscholar   +1 more source

New 19 bp deletion polymorphism in intron‐1 of dihydrofolate reductase (DHFR): A risk factor for spina bifida acting in mothers during pregnancy?

American Journal of Medical Genetics. Part A, 2004
W. Johnson, E. Stenroos, J. Spychala, S. Chatkupt, Sue X Ming, S. Buyske   +5 more
semanticscholar   +1 more source

New imidazolone derivatives comprising a benzoate or sulfonamide moiety as anti-inflammatory and antibacterial inhibitors: Design, synthesis, selective COX-2, DHFR and molecular-modeling study

Bioorganic Chemistry, 2020
Nadia Hanafy Metwally
exaly  

Benzothiazole analogues: Synthesis, characterization, MO calculations with PM6 and DFT, in silico studies and in vitro antimalarial as DHFR inhibitors and antimicrobial activities

Bioorganic and Medicinal Chemistry, 2017
Parth Thakor, Vasudev R Thakkar
exaly  

The 19‐bp deletion polymorphism in intron‐1 of dihydrofolate reductase (DHFR) may decrease rather than increase risk for spina bifida in the Irish population

American Journal of Medical Genetics. Part A, 2007
A. Parle‐McDermott, F. Pangilinan, J. Mills, P. Kirke, E. Gibney, J. Troendle, V. O’Leary, A. Molloy, M. Conley, J. Scott, L. Brody   +10 more
semanticscholar   +1 more source

Nonclassical antifolates, part 4. 5-(2-Aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling study

European Journal of Medicinal Chemistry, 2013
Ghada S Hassan, Shahenda M El-Messery, Yasmin S Abulfadl   +2 more
exaly  

Synthesis, biological evaluation and molecular modeling study of new (1,2,4-triazole or 1,3,4-thiadiazole)-methylthio-derivatives of quinazolin-4(3 H )-one as DHFR inhibitors

Bioorganic Chemistry, 2017
Shahenda M El-Messery, Heba A Ewida, Ghada S Hassan   +2 more
exaly  

A Distinct G1 Step Required to Specify the Chinese Hamster DHFR Replication Origin

Science, 1996
Jiarui Wu, D. Gilbert
semanticscholar   +1 more source

In silico ADMET study, docking, synthesis and antimalarial evaluation of thiazole-1,3,5-triazine derivatives as Pf-DHFR inhibitor

Pharmacological Reports, 2019
Supriya Sahu, Surajit Kumar Ghosh, Prashant Gahtori   +2 more
exaly  

Nonclassical antifolates, part 5. Benzodiazepine analogs as a new class of DHFR inhibitors: Synthesis, antitumor testing and molecular modeling study

European Journal of Medicinal Chemistry, 2014
Hussein I El-Subbagh, Ghada S Hassan, Shahenda M El-Messery   +2 more
exaly