Results 231 to 240 of about 20,409 (275)

Determination of di-(2-ethylhexyl)phthalate in human placenta

Journal of Chromatography A, 1977
A simple method has been devised for the analysis of di-(2-ethylhexyl)phthalate (DEHP) in human placenta which relies entirely on three rapid partition steps prior to gas chromatography with electron capture detection. The use of adsorption chromatography with all its attendant disadvantages for sample clean-up is eliminated in this procedure ...
C F, Poole, D G, Wibberley
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DI-2-Ethylhexyl Phthalate and Endocrine Disruption: A Review

Current Drug Targets - Immune, Endocrine & Metabolic Disorders, 2004
Esters of o-phthalic acid are widely distributed in the ecosystem. The phthalate acid esters (PAE's) are used as plasticizers in enormous quantities for a variety of industrial uses in the formulation of plastics. They are also used as solvents in certain industrial processes and as vehicles for pesticides and have been described as being among the ...
Giuseppe, Latini, Alberto, Verrotti, Claudio, De Felice   +2 more
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Comment on the carcinogenic potential of Di(2‐ethylhexyl) phthalate

Journal of Toxicology and Environmental Health, 1982
Analysis of the carcinogen bioassay of di(2-ethylhexyl) phthalate (DEHP) has shown that the designated maximum tolerated dose was exceeded in the low- and high-dose groups of male rats, in the high-dose group of female rats, and in the low- and high-dose groups of female mice.
S, Northup, L, Martis, R, Ulbricht, J, Garber, J, Miripol, T, Schmitz   +5 more
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Polar metabolites of Di-(2-ethylhexyl)phthalate in the rat

Biochimica et Biophysica Acta (BBA) - General Subjects, 1983
Di-(2-ethylhexyl)phthalate (DEHP) is an important industrial chemical widely used as a plasticizer for vinyl and other plastics. DEHP is extensively metabolized by mammals, different species showing dramatic differences in metabolite distributions. Previous studies of the metabolism in rats led to the suggestion that the enzymatic processes normally ...
P W, Albro, I, Tondeur, D, Marbury, S, Jordan, J, Schroeder, J T, Corbett   +5 more
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The Impact of Di(2-ethylhexyl)phthalate on Cancer Progression

Archivum Immunologiae et Therapiae Experimentalis, 2017
Di(2-ethylhexyl)phthalate (DEHP), a widely used plasticizer, mainly serves as an additive to render polyvinyl chloride (PVC) soft and flexible. PVC plastics have become ubiquitous in our modern society. Yet, the leaching of DEHP from PVC-based consumables ultimately results in the deposition in certain tissues via inadvertent applications. Health risks
Chon-Kit Chou, Ya-Ting Yang, Ho-Chun Yang, Shih-Shin Liang, Tsu-Nai Wang, Po-Lin Kuo, Hui-Min David Wang, Eing-Mei Tsai, Chien-Chih Chiu   +8 more
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Reversibility of the Chronic Effects of Di(2-ethylhexyl)phthalate

Toxicologic Pathology, 2001
Fischer-344 rats treated with 12,500 ppm (728 and 879 mg/kg/d for male and females, respectively) and B6C3F1 mice treated with 6,000 ppm (1,227 and 1,408 mg/kg/d, respectively) di(2-ethylhexyl)phthalate (DEHP) in the diet for 78 weeks were allowed to recover for an additional 26 weeks on control diet.
R M, David, M R, Moore, D C, Finney, D, Guest   +3 more
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Excretion and metabolism of di(2-ethylhexyl)-phthalate in man

Xenobiotica, 1985
Di-(2-ethylhexyl)phthalate (DEHP) taken orally by two volunteers (30 mg each) was excreted in the urine to the extent of 11 and 15% of dose. After enzymic hydrolysis the urinary metabolites (derivatives of mono (2-ethylhexyl)phthalate) were methylated and identified by g.l.c.-mass spectrometry (C.I.), and the quantitative distribution of conjugated and
P, Schmid, C, Schlatter
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Mass spectrometry of di-(2-ethylhexyl)phthalate metabolites

Biological Mass Spectrometry, 1980
The electron impact, methane positive chemical ionization, oxygen negative chemical ionization and collision induced dissociation mass analyzed ion kinetic energy spectra of nine metabolites of di-(2-ethylhexyl)phthalate are presented. The collision induced dissociation mass analyzed ion kinetic energy spectra of selected fragment ions were useful for ...
D J, Harvan, J R, Hass, P W, Albro, M D, Friesen   +3 more
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Exposure of hemodialysis patients to di-2-ethylhexyl phthalate

International Journal of Pharmaceutics, 1999
The migration of di-2-ethylhexyl phthalate (DEHP) from dialyzers was studied in 21 patients with chronic renal failure undergoing maintenance hemodialysis. The circulating concentrations of DEHP were measured by high performance liquid chromatography in blood of patients obtained from the inlet and the outlet of the dialyzer during a 4-h dialysis ...
M A, Faouzi, T, Dine, B, Gressier, K, Kambia, M, Luyckx, D, Pagniez, C, Brunet, M, Cazin, A, Belabed, J C, Cazin   +9 more
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BIOTRANSFORMATION OF DI(2-ETHYLHEXYL)PHTHALATE BY RAINBOW TROUT

Environmental Toxicology and Chemistry, 1995
AbstractThe biotransformation of di(2-ethylhexyl)phthalate (DEHP) was studied in rainbow trout (Oncorhynchus mykiss) following intravascular administration. Methyl-esterified metabolites were identified using rodent-derived standards and nonlinear gradient elution HPLC; metabolites were confirmed by gas chromatography.
Mace G. Barron, Phillip W. Albro, William L. Hayton   +2 more
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