Results 101 to 110 of about 1,595,796 (305)

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit, Daphna Idan, Ariel Avraham Hasidim, Tal Michael, Amalia Levy, Gali Pariente, Eitan Lunenfeld, Sharon Daniel   +7 more
wiley   +1 more source

Risk Factors for Gestational Diabetes in Pregnant Women: A case-control study

Payesh, 2019
Objective (s): About 90% of diabetes cases during pregnancy are due to gestational diabetes. This study aimed to assess risk factors for gestational diabetes in pregnant women.
Kobra Doostifar, Maryam Parsanahad, Khadijeh Baharzadeh, Fatemeh Khadem, Kambiz AhmadiAngali, Marzieh Araban   +5 more
doaj  

Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta

Clinical Pharmacology &Therapeutics, EarlyView.
Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung, Nicholas Ieronimakis, Bothaina Mousa, Emily D. Sheikh, Sarah E. Ligon, Joshua W. Monson, Jennifer R. Damicis, Hillary J. Kinsman, Lydia E. Bettridge, Samuel L.M. Arnold, Edward J. Kelly, Jashvant D. Unadkat, Joanne Wang   +12 more
wiley   +1 more source

Chronic hypertension with gestational diabetes mellitus: What about complications?

American Journal of Experimental and Clinical Research, 2016
The aim of this study was to evaluate the impact of chronic hypertension and gestational diabetes on pregnancy outcomes. We conducted a historical cohort study of 334 women undergoing singleton births in a Portuguese tertiary care center in Lisbon during
Ana Correia Campos, Ana Catarina Massa, Ricardo Rangel, Manuela Cardoso, Maria Augusta Borges   +4 more
doaj  

Maternal birth weight as an indicator of early and late gestational diabetes mellitus: The Japan Environment and Children's Study

Journal of Diabetes Investigation
Aims This study aimed to investigate the association of maternal birth weight (MBW) with early and late gestational diabetes mellitus (GDM). Methods A total of 69318 pregnant Japanese women were included in this birth cohort study.
Kazuma Tagami, Noriyuki Iwama, Hirotaka Hamada, Hasumi Tomita, Rie Kudo, Natsumi Kumagai, Hongxin Wang, Seiya Izumi, Zen Watanabe, Mami Ishikuro, Taku Obara, Nozomi Tatsuta, Hirohito Metoki, Chiharu Ota, Takashi Sugiyama, Shinichi Kuriyama, Takahiro Arima, Nobuo Yaegashi, Masatoshi Saito, The Japan Environment and Children's Study Group   +19 more
doaj   +1 more source

Medication Use During Breastfeeding—An Understudied Population: A Five‐Year Experience in the Pharmacovigilance Center of Lyon

Clinical Pharmacology &Therapeutics, EarlyView.
Medication use during breastfeeding is common, yet data on drug transfer into breast milk and infant exposure remain limited. This study describes real‐world requests concerning medication compatibility with breastfeeding managed by the Lyon pharmacovigilance center over five years.
Blandine Bertin, Aurore Gouraud, Anthony Facile, Fanny Ledys, Sabrina Pierre, Véronique Pizzoglio, Thierry Vial, Marine Auffret, Marina Atzenhoffer   +8 more
wiley   +1 more source

Determinants of recurrence in gestational diabetes mellitus

, 2020
Gestational Diabetes Mellitus is any degree of glucose intolerance that is diagnosed for the first time during pregnancy or starts during pregnancy. Gestational Diabetes Mellitus adversely affects maternal and fetus health.
Pekkolay, Zafer
core   +1 more source

Association of ABO blood group with gestational diabetes mellitus in Pakistan: a case control study

Journal of the Pakistan Medical Association
Objective: To investigate the association between blood group and development of gestational diabetes mellitus among pregnant women. Method: The retrospective, case-control study was conducted from August 2021 to May 2022 at The Aga Khan Hospital for ...
Erum Saleem, Sanum Napper, Sheikh Irfan, Amir Raza   +3 more
doaj   +1 more source

The Therapeutic Effect of Zuogui Wan in Gestational Diabetes Mellitus Rats

Journal of Analytical Methods in Chemistry, 2014
In this experiment, we established an animal model of gestational diabetes mellitus rats using streptozotocin. Using the rat model of GDM, the pregnant rats in 1-19d were divided into three groups: (1) Zuogui Wan gestational diabetes mellitus group ...
Yuwei Wang, Qianjin Feng, Xin Niu, Xinshe Liu, Kaixia Xu, Xiangzhu Yang, Huifeng Wang, Qiuju Li   +7 more
doaj   +1 more source

Unbound Intrinsic Formation Clearance of 6β‐Hydroxycortisol Is a Useful Biomarker of CYP3A4 Activity during Pregnancy

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnancy results in multiple physiological changes that impact drug disposition. For example, hepatic CYP3A activity and renal transporter‐mediated clearance increase in late pregnancy, but the time course of these changes across pregnancy is not known.
Aurora K Authement, Mary F Hebert, Emily E Fay, Nina Isoherranen   +3 more
wiley   +1 more source