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Type 2 diabetes is a growing health concern for children as well as adults in the United States. Diabetes that is uncontrolled can lead to blindness, kidney disease, heart disease, and amputations. Early treatment to control blood glucose levels helps decrease a person’s chances of developing these health problems.
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Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová+11 more
wiley +1 more source
Diabetes is a risk factor for the progression and prognosis of COVID‐19
To figure out whether diabetes is a risk factor influencing the progression and prognosis of 2019 novel coronavirus disease (COVID‐19).
Wei-na Guo+13 more
semanticscholar +1 more source
Dipeptidyl-peptidase 4 (DPP4) is a glycoprotein of 110 kDa, which is ubiquitously expressed on the surface of a variety of cells. This exopeptidase selectively cleaves N-terminal dipeptides from a variety of substrates, including cytokines, growth factors, neuropeptides, and the incretin hormones.
Röhrborn, Diana+2 more
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Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao+7 more
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In the accompanying comment letter (1), Weinert summarizes published data from the Brazilian Gestational Diabetes Study (2) and comments on applying International Association of Diabetes and Pregnancy Study Groups (IADPSG) Consensus Panel recommendations
B. Metzger+14 more
semanticscholar +1 more source
Diabetic Ketoacidosis Without Diabetes [PDF]
Type B insulin resistance syndrome is a rare disease that occurs due to the development of autoantibodies to the insulin receptor and can result in either severe insulin resistance and hyperglycemia or, conversely, hypoglycemia. Diabetes mellitus is often severe, usually transient, and poorly responsive to exogenous insulin. Diabetic ketoacidosis is an
Chan Kim+3 more
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Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti+8 more
wiley +1 more source
Differences in level of confidence in diabetes care between different groups of trainees: the TOPDOC diabetes study [PDF]
Background There is an increasing prevalence of diabetes. Doctors in training, irrespective of specialty, will have patients with diabetes under their care.
George, Jyothis T+10 more
core +1 more source