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Discusión

open access: yesRevista Colombiana de Endocrinología, Diabetes y Metabolismo, 2018
Doctor Otero. — Hay varias preguntas en la mesa para el doctor De Nogales, la primera dice: ¿Cuál fue la diferencia encontrada en cuanto a adaptación se refiere entre los pacientes recibiendo Insulina y pacientes con Hipoglicemiantes orales ...
Asociación Colombiana de Diabetes
doaj   +1 more source

The Double Burden. [PDF]

open access: yes, 2013
One third of the world's population is latently infected with Mycobacterium tuberculosis, and with the lifestyle changes succeeding the on-going urbanization, populations already burdened by tuberculosis are experiencing a dramatic increase in chronic ...
Faurholt-Jepsen, Daniel
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Diabetes, Diabetes, and the American Diabetes Association [PDF]

open access: yesDiabetes, 1995
Now at the end of my tenure as editor of Diabetes, I wish to offer some personal thoughts about our journal, the disease we oppose, and our Association. I am pleased, but not satisfied, with our journal. I am disappointed, but not surprised, that the disease remains recalcitrant. I am concerned, but optimistic, about our Association. The challenges are
openaire   +2 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

News form the 35th annual meeting of the European Association on Study of Diabetes

open access: yesСахарный диабет, 2000
С 28 сентября по 2 октября 1999 г. в Брюсселе (Бельгия) проходила 35-я конференция Европейской Ассоциации по изучению сахарного диабета (СД). Программа конференции включала все вопросы клинической и экспериментальной диабетологии. Большой интерес вызвали
Editorial team Diabetes Mellitus
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Interventions for prevention of type 2 diabetes in relatives:A systematic review [PDF]

open access: yes, 2017
The relatives and partners of people with type 2 diabetes are at increased risk of developing type 2 diabetes. This systematic review examines randomized controlled trials, written in English that tested an intervention, which aimed to modify behaviors ...
Dimova, Elena Dimcheva   +3 more
core   +4 more sources

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

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