Results 51 to 60 of about 3,142,333 (299)

Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer [PDF]

, 2017
The relationships between diabetes and pancreatic ductal adenocarcinoma (PDAC) are complex. Longstanding type 2 diabetes (T2DM) is a risk factor for pancreatic cancer, but increasing epidemiological data point to PDAC as also a cause of diabetes due to ...
Chari, Suresh T., Murray Korc, Andersen, Dana K., Eibl, Guido, Michael R. Rickels, Dana K. Andersen, Andersen, Dana K, Petersen, Gloria M., Rickels, Michael R., Suresh T. Chari, Donghui Li, Korc, Murray, Chari, Suresh T, Abbruzzese, James L, Petersen, Gloria M, James L. Abbruzzese, Gloria M. Petersen, Guido Eibl, Rickels, Michael R, Li, Donghui, Abbruzzese, James L.   +20 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

JAMBUL IN DIABETES; SACCHARINE IN DIABETES. [PDF]

The Lancet, 1887
n ...
openaire   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Discusión

Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2018
Doctor Otero. — Hay varias preguntas en la mesa para el doctor De Nogales, la primera dice: ¿Cuál fue la diferencia encontrada en cuanto a adaptación se refiere entre los pacientes recibiendo Insulina y pacientes con Hipoglicemiantes orales ...
Asociación Colombiana de Diabetes
doaj   +1 more source

Childhood diabetes database. Chinese

, 2007
Translation of: Childhood diabetes database.Title from PDF caption (viewed on May 12, 2009)."Chinese DHS 8581 (Rev.5/2007)."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Identification of Type 1 Diabetes-Associated DNA Methylation Variable Positions That Precede Disease Diagnosis [PDF]

, 2011
Monozygotic (MZ) twin pair discordance for childhood-onset Type 1 Diabetes (T1D) is similar to 50%, implicating roles for genetic and non-genetic factors in the aetiology of this complex autoimmune disease.
Busato, F, Manfras, B, Kerith-rae M, Leslie, R. David, Jörg Tost, Manfras Burkhard, Mohammed I Hawa, Thomas A. Down, Maslau, S, Leslie, RD, Mohammed I. Hawa, Bernhard O Boehm, Beck Stephan, Rakyan, VK, Aden Deeqo, Daunay, A, Maslau Siarhei, Down Thomas A., Dias, Kerith-Rae M., Bell, Christopher G., Rakyan, Vardhman K., Boehm, Bernhard O., Beck, S, Bell Christopher G., Leslie R. David, Charles A. Mein, Charles A Mein, Boehm Bernhard O., Vardhman K Rakyan, Beyan, H, Burkhard Manfras, Christopher G. Bell, Hawa, MI, Kerith-Rae M. Dias, Vardhman K. Rakyan, R David Leslie, Kerith-Rae M Dias, Siarhei Maslau, Hawa Mohammed I., Busato Florence, Deeqo Aden, Bell, CG, Beck, Stephan, Stephan Beck, Bernhard O. Boehm, Busato, Florence, Dias Kerith-Rae M., Tost Jörg, Mein, Charles A., Christopher G Bell, Dias, KRM, Tost, J, Maslau, Siarhei, Hawa, Mohammed I., Daunay, Antoine, R. David Leslie, Florence Busato, Down, Thomas A., Rakyan Vardhman K., Tost, Jörg, Mein, CA, Daunay Antoine, Beyan, Huriya, Down, TA, Boehm, BO, Huriya Beyan, Antoine Daunay, Mein Charles A., Manfras, Burkhard, Thomas A Down, Beyan Huriya, Aden, D, Aden, Deeqo   +72 more
core   +2 more sources

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Skin autofluorescence in diabetes mellitus [PDF]

, 2008
AGEs ofwel advanced glycation endproducts zijn onomkeerbaar versuikerde stoffen, die voornamelijk aan eiwitten zijn gekoppeld, en die bij ieder mens stapelen. Bij iemand met diabetes mellitus gaat dit proces echter versneld.
Lutgers, Helen Lucia, Lutgers, H.L.,, Lutgers, H.L.   +2 more
core   +14 more sources