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Aquaporins in Diabetes Insipidus

2023
Disruption of water and electrolyte balance is frequently encountered in clinical medicine. Regulating water metabolism is critically important. Diabetes insipidus (DI) presented with excessive water loss from the kidney is a major disorder of water metabolism.
H A Jenny, Lu, Jinzhao, He
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Adipsic diabetes insipidus

2021
Adipsic diabetes insipidus (ADI) is a rare but devastating disorder of water balance with significant associated morbidity and mortality. Most patients develop the disease as a result of hypothalamic destruction from a variety of underlying etiologies.
Vallari, Kothari   +2 more
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Diabetes Insipidus

2018
Diabetes insipidus, characterized by the excretion of copious volumes of unconcentrated urine, results from a deficiency in the action of the antidiuretic hormone arginine vasopressin and can be caused by any of four fundamentally different defects, including impaired secretion (neurohypophyseal diabetes insipidus), impaired renal response (nephrogenic
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NEPHROGENIC DIABETES INSIPIDUS

Pediatrics, 1955
1. Two cases of congenital diabetes insipidus resistant to pitressin, or diabetes insipidus of the nephrogenic type, occurring in male cousins during infancy have been described in which the most striking manifestations were recurrent pyrexia, polyuria, polydipsia, poor weight gain and development and hyperelectrolytemia. 2.
J R, WEST, J G, KRAMER
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Diabetes Insipidus

2017
Disruption of water and electrolyte balance is frequently encountered in clinical medicine. Regulating water metabolism is critically important. Diabetes insipidus (DI) presented with excessive water loss from the kidney is a major disorder of water metabolism. To understand the molecular and cellular mechanisms and pathophysiology of DI and rationales
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Nephrogenic Diabetes Insipidus

Advances in Chronic Kidney Disease, 1998
Nephrogenic diabetes insipidus (NDI), which can be inherited or acquired, is characterized by an inability to concentrate urine despite normal or elevated plasma concentrations of the antidiuretic hormone arginine vasopressin (AVP). Polyuria, with hyposthenuria, and polydipsia are the cardinal clinical manifestations of the disease.
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Diabetes Insipidus in a Cow

Journal of the American Veterinary Medical Association, 1979
SUMMARY Diabetes insipidus was diagnosed in a 6-year-old Holstein-Friesian cow with a history of recurrent fever, ketosis, lymphadenopathy, and inappetence. The diagnosis was based on the clinical findings, response to exogenous vasopressin, and lack of urine concentration in a water deprivation test.
C E, Wallace, G J, Kociba
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Nephrogenic diabetes insipidus

Current Opinion in Nephrology and Hypertension, 2000
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Deen, P.M.T.   +3 more
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Diabetes Insipidus

2011
Diabetes insipidus is characterized by polyuria, urine hypotonicity, and hypernatremia. Central diabetes insipidus results from a lack of antidiuretic hormone (ADH); nephrogenic diabetes insipidus results from renal insensitivity to ADH. In the intensive care unit (ICU), diabetes insipidus is most often caused by pituitary surgery, trauma, and brain ...
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Nephrogenic Diabetes Insipidus

Pediatrics In Review, 1996
Nephrogenic diabetes insipidus (NDI) is a disorder, either congenital or acquired, in which antidiuretic hormone (ADH) secretion is normal, but the ability to concentrate urine is reduced because of insensitivity of the collecting tubule to ADH. The antidiuretic action of arginine vasopressin requires binding of the hormone to the renal type V2 ...
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