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Beyond Biomarkers: Blending Copeptin and Clinical Cues to Distinguish Central Diabetes Insipidus from Primary Polydipsia in Children. [PDF]
BiomedicinesCiortea DA +6 more
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Nature Reviews Disease Primers, 2019 Diabetes insipidus (DI) is a disorder characterized by excretion of large amounts of hypotonic urine. Central DI results from a deficiency of the hormone arginine vasopressin (AVP) in the pituitary gland or the hypothalamus, whereas nephrogenic DI results from resistance to AVP in the kidneys.
Morris Goldman +2 more
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Endocrinology and Metabolism Clinics of North America, 2020 Bettina Winzeler +2 more
exaly +3 more sources
Familial forms of diabetes insipidus: clinical and molecular characteristics [PDF]
Nature Reviews Endocrinology, 2011 Over the past two decades, the genetic and molecular basis of familial forms of diabetes insipidus has been elucidated. Diabetes insipidus is a clinical syndrome characterized by the excretion of abnormally large volumes of diluted urine (polyuria) and ...
Muriel Babey +2 more
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Critical Care Medicine, 1992
To review the pathophysiology, diagnosis, and treatment of the syndromes of diabetes insipidus with an emphasis on those situations likely to be encountered in the critical care setting.Extensive clinical experience and relevant publications from the English literature identified via MEDLINE search, citation in reviews, publications of original data ...
L S, Blevins, G S, Wand
openaire +2 more sources
To review the pathophysiology, diagnosis, and treatment of the syndromes of diabetes insipidus with an emphasis on those situations likely to be encountered in the critical care setting.Extensive clinical experience and relevant publications from the English literature identified via MEDLINE search, citation in reviews, publications of original data ...
L S, Blevins, G S, Wand
openaire +2 more sources
Baillière's Clinical Endocrinology and Metabolism, 1995
The advances in our understanding of the pathophysiology of defects in the antidiuretic hormone, the V2 receptor and the water channel, owing to mutations in the prepro-AVP-NPII, AVPR2 and AQP2 genes respectively, is providing insight into inherited diabetes insipidus as well as the more numerous sporadic cases.
G N, Hendy, D G, Bichet
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The advances in our understanding of the pathophysiology of defects in the antidiuretic hormone, the V2 receptor and the water channel, owing to mutations in the prepro-AVP-NPII, AVPR2 and AQP2 genes respectively, is providing insight into inherited diabetes insipidus as well as the more numerous sporadic cases.
G N, Hendy, D G, Bichet
openaire +2 more sources
Hormone Research in Paediatrics, 2003
Diabetes insipidus is a heterogeneous condition characterized by polyuria and polydipsia caused by a lack of secretion of vasopressin, its physiological suppression following excessive water intake, or kidney resistance to its action. In many patients, it is caused by the destruction or degeneration of the neurons that originate in the supraoptic and ...
openaire +5 more sources
Diabetes insipidus is a heterogeneous condition characterized by polyuria and polydipsia caused by a lack of secretion of vasopressin, its physiological suppression following excessive water intake, or kidney resistance to its action. In many patients, it is caused by the destruction or degeneration of the neurons that originate in the supraoptic and ...
openaire +5 more sources