Results 61 to 70 of about 450,013 (310)

Circadian gene variants and susceptibility to type 2 diabetes : a pilot study [PDF]

, 2012
Background Disruption of endogenous circadian rhythms has been shown to increase the risk of developing type 2 diabetes, suggesting that circadian genes might play a role in determining disease susceptibility.
O’Hare J. Paul, Shahrad Taheri (57360), M. Ann Kelly (174447), Shera, A. Samad, Hydrie MZ, Barnett, Anthony H., Taheri, S., Anthony H Barnett, Kumar S, Shera, A.S., Rees, Simon D., Kelly, M. Ann, Kelly, Marilyn, Shera, AS, Raychaudhuri, Soumya, Sudhesh Kumar (89490), Abdul Basit (174463), Bellary, Srikanth, Rees, S.D., Kumar, S., Barnett AH, J Paul O'Hare, M. Zafar I. Hydrie (174450), Basit, A., Bellary Srikanth, O'Hare, JP, Bellary S, Shera, A Samad, Taheri S, DIAGRAM Consortium, Hydrie, MZ, Taheri, Shahrad, M Zafar I Hydrie, Bellary, S., Abdul Basit, Hydrie M. Zafar I., Shera A. Samad, Barnett, Anthony, Bellary, S, Basit Abdul, Basit, A, Rees SD, Kumar Sudhesh, Srikanth Bellary (89487), Rees, Simon D, Sudhesh Kumar, Shahrad Taheri, O'Hare, J Paul, Rees, Simon, Kelly, M Ann, SAT2D Consortium, Hydrie, M.Z.I., Kelly MA, A Samad Shera, Basit, Abdul, Barnett, A.H., Anthony H. Barnett (174467), Rees Simon D., Kelly, M.A., Srikanth Bellary, Shera AS, Basit A, Hydrie, M Zafar I, Hydriem, Zafar L., Kumar, Sudhesh, Barnett, Anthony H, O'Hare, J.P., Kelly M. Ann, Hydrie, M. Zafar I., Simon D Rees, Kumar, S, A. Samad Shera (174452), O'Hare, J. Paul, Taheri Shahrad, Barnett Anthony H., J. Paul O’Hare (174457), M Ann Kelly, Simon D. Rees (174448)   +77 more
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Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Renal hypertrophy in experimental diabetes mellitus

Kidney International, 1983
The kidney changes seen in rats shortly after the induction of experimental diabetes were reviewed: Kidney weight increases by 15 to 20% during the first 4 to 5 days of diabetes and by 70 to 90% after some weeks. GFR increases after a lag-time of some days in parallel to kidney weight.
openaire   +2 more sources

The clinical and cost-effectiveness of patient education models for diabetes: a systematic review and economic evaluation [PDF]

, 2003
This systematic review examines the clinical and cost-effectiveness of patient education models for adults with Type 1 or Type 2 diabetes.Epidemiology and backgroundDiabetes mellitus (diabetes) is characterised by a state of chronic hyperglycaemia ...
P Royle, N Waugh, E Loveman, Dunn, N., Dunn, N, Cave, C. (Carolyn), Royle, P, Loveman, E, Waugh, N, Loveman, E., Green , C., Waugh, Norman, Cave, C, Green, C, Royle, Pamela, C Green, C Cave, N Dunn   +17 more
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Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli, Cecilia Nalli, Francesca Crisafulli, Carlo Garaffoni, Marcello Govoni, Giulia Voltarel, Alba C. Pozzi, Beatrice Maranini, Ettore Silvagni, Alessandra Bortoluzzi, Angela Tincani   +10 more
wiley   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Telomere length attrition, a marker of biological senescence, is inversely correlated with triglycerides and cholesterol in South Asian males with type 2 diabetes mellitus [PDF]

, 2012
South Asians have a higher risk of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) than white Caucasians, for a given BMI. Premature biological ageing, assessed by reduction in telomere length (TL), may be mediated by factors resulting ...
Miller, M.A., da Silva, NF, Barnett, Anthony H., Al-Attas, O., Miller, MA, da Silva, Nancy F., Kelly, M. Ann, Tripathi, G, Al-Attas, Omar S., Al-Daghri, Nasser M., Cappuccio, Francesco, Kelly, Ann M., Bellary, Srikanth, Kumar, S., da Silva, N.F., McTernan, Philip G., Sabico, S, O'Hare, JP, Tripathi, Gyanendra, Cappuccio, Francesco P., McTernan, P. G., Alokail, M., Al-Daghri, NM, Al-Attas, Omar, Miller, Michelle A., Al-Daghri, N.M., Harte, A.L., Bellary, S., Barnett, Anthony, Bellary, S, Al-Daghri, Nasser M, Kelly, A., Sabico, Shaun, McTernan, PG, Alokail, Majed S., Al-Attas, O, Alokail, M, Tripathi, G., Barnett, A.H., Harte, AL, Harte, Alison L., Kelly, A, O'Hare, Joseph P., Kumar, Sudhesh, O'Hare, J.P., Sabico, S., Cappuccio, FP, Alokail, Majed, McTernan, P.G., Kumar, S, O'Hare, J. Paul, Cappuccio, F.P.   +51 more
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Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Neuroprotective Effect of Hydroxytyrosol in Experimental Diabetes Mellitus

Journal of Agricultural and Food Chemistry, 2017
The aim of the study was to analyze the possible neuroprotective effect of hydroxytyrosol (HT) in diabetic animals in a model of hypoxia-reoxygenation. Rats (10 animals/group) were distributed in five groups: nondiabetic rats, control diabetic rats (DR), and DR rats treated for 2 months with 1, 5, or 10 mg/kg/day po HT.
Reyes, J.J., Villanueva, B., López-Villodres, J.A., De La Cruz, J.P., Romero, L., Rodríguez-Pérez, M.D., Rodríguez-Gutiérrez, Guillermo, Fernández-Bolaños Guzmán, Juan, González-Correa, J.A.   +8 more
openaire   +3 more sources

Vitamina D e sua relação com a resistência à ação da insulina em portadores de diabetes mellitus tipo 2 [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Nutrição, Florianópolis, 2014Objetivo: Avaliar a relação entre a concentração sérica e o consumo alimentar de vitamina D com a ...
Rech, Camila
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