Results 101 to 110 of about 1,168,236 (313)

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source

Global cognition and executive functions of older adults with type 1 diabetes mellitus without dementia

Journal of Diabetes Investigation
Aims/Introduction This study aimed to characterize the global cognition and executive functions of older adults with type 1 diabetes mellitus in comparison with type 2 diabetes mellitus.
Kaoru Nagasawa, Kimio Matsumura, Takayasu Uchida, Yuya Suzuki, Akihiro Nishimura, Minoru Okubo, Yukifusa Igeta, Tetsuro Kobayashi, Takashi Sakurai, Yasumichi Mori   +9 more
doaj   +1 more source

Déficits de autocuidado vivenciados por familias de crianças e adolescentes com diabetes mellitus tipo 1 [PDF]

, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-graduação em EnfermagemEste estudo constitui-se de uma pesquisa qualitativa do tipo convergente assistencial, realizada com oito famílias de ...
Mello, Maria Berra de
core  

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

Classic Type 1 Diabetes Mellitus and Fulminant Type 1 Diabetes Mellitus: Similarity and Discrepancy of Immunological Characteristics and Cytokine Profile

Diabetes, Metabolic Syndrome and Obesity, 2021
Lingwen Ying,1,* Yong Zhang,2,* Jun Yin,1,* Yufei Wang,1 Wei Lu,1 Wei Zhu,1 Yuqian Bao,1 Jian Zhou1 1Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital; Shanghai Clinical Center for ...
Ying L, Zhang Y, Yin J, Wang Y, Lu W, Zhu W, Bao Y, Zhou J   +7 more
doaj  

NPY Levels In Type 1 Diabetic Men of Different Duration.

, 2011
Background: The aim of the present study was to evaluate whether the different duration of type 1 diabetes mellitus influences basal NPY secretion. Design: The NPY concentrations were measured in sixty-eight men with insulin-dependent diabetes mellitus ...
Lavinia Volpi, Anna Araldi, Maria Grazia Magotti, Paolo Chiodera, Riccardo Volpi, Luigi Capretti, Claudio Giumelli, Vittorio Coiro, Simona Cataldo, Teore Ferri, Roberta Minelli   +10 more
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Incidence of insulin-treated diabetes in Australia 2000-2011 [PDF]

, 2014
Australia\u27s rate of incidence of insulin-treated diabetes has remained stable over the last decade, with between 10 and 12 new cases per 100,000 population per year.

core  

Diabetes mellitus type 2 in urban Ghana: characteristics and associated factors. [PDF]

, 2012
BACKGROUND: Sub-Saharan Africa faces a rapid spread of diabetes mellitus type 2 (DM2) but its potentially specific characteristics are inadequately defined.
Spranger, J, Micah Frank, Bedu-Addo George, Mockenhaupt Frank P, Karl-Johann Terpe, Bedu-Addo, G, Ekkehart Dietz, Frank Micah, Amoako, YA, Ina Danquah, van der Giet, M, van der Giet Markus, Awuku Yaw A, Dietz, E, Micah, F, Yaw A Amoako, Terpe, KJ, Awuku, YA, Danquah, I, Mockenhaupt, FP, Danquah Ina, Joachim Spranger, Amoako Yaw A, George Bedu-Addo, Terpe Karl-Johann, Spranger Joachim, Markus van der Giet, Frank P Mockenhaupt, Dietz Ekkehart, Yaw A Awuku   +29 more
core   +1 more source

Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity

Advanced Science, EarlyView.
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang, Lingzhi Chen, Jing Xu, Jiaqi Yu, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Lang Rao, Jierong Chen, Junxia Zheng, Haibo Zhou   +12 more
wiley   +1 more source

The impact of type 2 diabetes and Microalbuminuria on future cardiovascular events in patients with clinically manifest vascular disease from the Second Manifestations of ARTerial Disease (SMART) study

, 2008
Aims Type 2 diabetes mellitus and microalbuminuria are important risk factors for cardiovascular disease (CVD). Whether these two complications are important and independent risk factors for future CVD events in a high-risk population with clinically ...
Graaf, Y., van der, Algra, A., van der Graaf, Y., Soedamah-Muthu, S.S., Visseren, F.L.J.   +4 more
core   +1 more source