British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Heart transplantation (HT) is frequently complicated by chronic kidney disease, of which tacrolimus‐related nephrotoxicity is an important cause. In kidney and liver transplant recipients, fast tacrolimus metabolism (defined as a low concentration‐to‐dose [C0/D] ratio), negatively affects kidney function.
Maaike R. Schagen +9 more
wiley +1 more source
Inducing Causal Structure for Interpretable Neural Networks Applied to Glucose Prediction for T1DM Patients [PDF]
arXivCausal abstraction techniques such as Interchange Intervention Training (IIT) have been proposed to infuse neural network with expert knowledge encoded in causal models, but their application to real-world problems remains limited. This article explores the application of IIT in predicting blood glucose levels in Type 1 Diabetes Mellitus (T1DM ...
arxiv
A case report: First presentation of diabetes mellitus type 1 with severe hyperosmolar hyperglycemic state in a 35-month-old girl. [PDF]
Clin Case Rep, 2021 Saeed A, Ilkhanipoor H.
europepmc +1 more source
Estimating the minimally important difference (MID) of the Diabetes Health Profile-18 (DHP-18) for Type 1 and Type 2 Diabetes Mellitus [PDF]
Aims: The DHP-18 is a widely used measure of health related quality of life in diabetes mellitus but it is unclear what constitutes a meaningful change in score on each domain. The aim of this study was to establish estimates for the minimally important
Meadows, K., Mulhern, B.
core
British Journal of Clinical Pharmacology, EarlyView.This review aimed to synthesize factors associated with medication nonadherence among people with type 2 diabetes (PwT2D), using the Capability, Opportunity, Motivation and Behaviour (COM‐B) model as the a priori model. Studies published between January 2014 and April 2024 were searched on five databases.
Vivien Teo, John Weinman, Kai Zhen Yap
wiley +1 more source
Self-care in children with newfound type 1 diabetes mellitus [PDF]
Innledning Type 1 diabetes mellitus er hyppigst utbredt blant barn (Sagen 2011), og i Norge er det over 300 barn som får diagnosen hvert år (Barn og diabetes 2015).
Lien, Kine Holm +2 more
core
British Journal of Clinical Pharmacology, EarlyView.Aims To characterize the pharmacokinetics (PK) and PK/pharmacodynamics (PD) regarding glycosylated haemoglobin (HbA1c) lowering using the paediatric data from DINAMO and to assess differences compared with adults. Methods Population PK and PK/PD models previously developed for empagliflozin in adults and adolescents were re‐estimated in a Bayesian ...
Juliane Rascher +7 more
wiley +1 more source
Physiological effects of intraperitoneal versus subcutaneous insulin infusion in patients with diabetes mellitus type 1: A systematic review and meta-analysis. [PDF]
PLoS One, 2021 Dirnena-Fusini I +4 more
europepmc +1 more source
Biotechnology and Bioengineering, EarlyView.Dash and coworkers have fabricated a small intestine on a chip, which encapsulates the physiology and biofilm of the small intestinal epithelium. The dynamic system showed villus differentiation within 5 days of flow, and the mucus layer and biofilm showed small intestinal characteristics.
Sanat Kumar Dash +2 more
wiley +1 more source
Diabetes Mellitus Type 1 has a Higher Impact on Corneal Endothelial Cell Density and Pachymetry than Diabetes Mellitus Type 2, Independent of Age: A Meta-Regression Model. [PDF]
Cornea, 2022 Amador-Muñoz DP +4 more
europepmc +1 more source