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Biomolecules, 2021 Catalpol isolated from Rehmannia glutinosa is a potent antioxidant and investigated against many disorders. This review appraises the key molecular pathways of catalpol against diabetes mellitus and its complications.
Subrat Kumar Bhattamisra +4 more
doaj +1 more source
Genetics and Pathophysiology of Maturity-onset Diabetes of the Young (MODY): A Review of Current Trends [PDF]
arXiv, 2021 Single gene mutations have been implicated in the pathogenesis of a form of diabetes mellitus (DM) known as the maturity-onset diabetes of the young (MODY). However, there are diverse opinions on the suspect genes and pathophysiology, necessitating the need to review and communicate the genes to raise public awareness.
arxiv
Genetics of type 1 diabetes mellitus [PDF]
Genes & Immunity, 2002 At least 20 different chromosomal regions have been linked to type 1 diabetes (T1D) susceptibility in humans, using genome screening, candidate gene testing, and studies of human homologues of mouse susceptibility genes. The largest contribution from a single locus (IDDM1) comes from several genes located in the MHC complex on chromosome 6p21.3 ...
Michael F. McDermott, Flemming Pociot
openaire +2 more sources
Real life with type 1 diabetes mellitus
Indian Journal of Endocrinology and Metabolism, 2015 Type 1 diabetes mellitus (T1DM) is a form of diabetes mellitus that results from the autoimmune destruction of the insulin-producing beta cells in the pancreas.
Deepak Yagnik
doaj +1 more source
Association of time in range with hemoglobin A1c, glycated albumin and 1,5‐anhydro‐d‐glucitol
Journal of Diabetes Investigation, 2021 Aims/Introduction Hemoglobin A1c (HbA1c), glycated albumin (GA) and 1,5‐anhydro‐d‐glucitol (1,5‐AG) are used as indicators of glycemic control, whereas continuous glucose monitoring (CGM) is used to assess daily glucose profiles.
Mana Ohigashi +10 more
doaj +1 more source
Relationship between Plasma Hypoxia Inducible Factor 1α in Type 2 Diabetes Mellitus with Malignancy and Without Malignancy [PDF]
, 2020 BACKGROUND: Diabetes mellitus was associated with hypoxia condition and result ischemia and induced neovascularization and other forms of the cell adaptation in response to the tissue concentrations of low oxygen levels.
Ardinata, Dedi +3 more
core +2 more sources
Misdiagnosis of type 1 diabetes mellitus [PDF]
International Journal of Pediatric Endocrinology, 2013 In the past type 1 Diabetes Mellitus is the commonest type of diabetes affecting children in Malaysia. Nevertheless, diagnosis of type 2 Diabetes Mellitus is increasingly being made due to the rising prevalence rate of obesity amongst children. This contributes to the difficulty in making the right diagnosis at initial presentation if the clinical ...
Muhamad Yazid Jalaludin +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang +5 more
wiley +1 more source
Factor Associated with Diabetes Burnout Syndrome Among Type 2 Diabetes Mellitus [PDF]
, 2020 Diabetes mellitus is a metabolic disease that is often found in Indonesia and the number of sufferers is increasing every time. Management of therapy patients with type 2 diabetes mellitus consists of five steps that require compliance and discipline to ...
Nuari, Nian Afrian
core +1 more source
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
FEBS Open Bio, EarlyView.Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu +6 more
wiley +1 more source