Results 51 to 60 of about 963,948 (277)

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

Advanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao, Weixian Hu, Shengming Zhang, Yuheng Liao, Kangkang Zha, Chenyan Yu, Zhenhe Zhang, Wenqian Zhang, Bobin Mi, Faqi Cao, Guohui Liu, Wu Zhou   +11 more
wiley   +1 more source

Artificial intelligence in type 1 diabetes mellitus

Journal of Education, Health and Sport
Type I diabetes is an autoimmune disease in the course of which insulin levels are reduced and hyperglycemia occurs. Treatment options for type I diabetes have changed a lot over time.
Wiktoria Łoskot, Jan Szwech, Mateusz Matczak, Karol Jasiński, Aleksandra Broda, Kacper Hoksa, Krzysztof Jodłowski, Ewa Dubniewicz, Paula Majewska, Alicja Staszek   +9 more
doaj   +1 more source

A Big Role for microRNAs in Gestational Diabetes Mellitus

Frontiers in Endocrinology, 2022
Maternal diabetes is associated with pregnancy complications and poses a serious health risk to both mother and child. Growing evidence suggests that pregnancy complications are more frequent and severe in pregnant women with pregestational type 1 ...
Matladi Masete, Matladi Masete, Stephanie Dias, Nompumelelo Malaza, Nompumelelo Malaza, Sumaiya Adam, Carmen Pheiffer, Carmen Pheiffer, Carmen Pheiffer   +8 more
doaj   +1 more source

Antioxidant level and redox status of coenzyme Q10 in the plasma and blood cells of children with diabetes mellitus type 1

Pediatric Diabetes, 2008
:  Hyperglycaemia has been reported to cause increased production of oxygen free radicals. Oxidative stress may contribute to the pathogenesis of diabetic complications. Coenzyme Q10 (CoQ10) is known for its key role in mitochondrial bioenergetics and is
T. Menke, P. Niklowitz, T. Wiesel, W. Andler   +3 more
semanticscholar   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

The Challenge of Type 1 Diabetes Mellitus [PDF]

ILAR Journal, 2004
Diabetes mellitus is a heterogeneous group of diseases characterized by high blood glucose levels due to defects in insulin secretion, insulin action, or both. With the number of cases expected to increase rapidly in the years to come, diabetes is a growing health challenge worldwide.
H. J. Schwartz, Larissa Eiselein, John C. Rutledge   +2 more
openaire   +3 more sources

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

Advanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin, Houxin Fan, Zhenchao Liu, Paolo Donati, Youssef Amin, Yap Wing Fen, Junbo Liang, Pier Paolo Pompa, Sailing He   +8 more
wiley   +1 more source

Quasi-Model-Based Control of Type 1 Diabetes Mellitus

Journal of Electrical and Computer Engineering, 2011
Glucose-insulin models appeared in the literature are varying in complexity. Hence, their use in control theory is not trivial. The paper presents an optimal controller design framework to investigate the type 1 diabetes from control theory point of view.
András György, Levente Kovács, Péter Szalay, Dániel A. Drexler, Balázs Benyó, Zoltán Benyó   +5 more
doaj   +1 more source

Real‐world risk factors of confirmed or probable COVID‐19 in Americans with diabetes: A prospective, community‐based study (iNPHORM)

Endocrinology, Diabetes & Metabolism, 2022
Introduction Americans with diabetes are clinically vulnerable to worse COVID‐19 outcomes; thus, insight into how to prevent infection is imperative. Using longitudinal, prospective data from the real‐world iNPHORM study, we identify the intrinsic and ...
Alexandria Ratzki‐Leewing, Jason E. Black, Bridget L. Ryan, Stewart B. Harris   +3 more
doaj   +1 more source