Results 51 to 60 of about 1,594,352 (310)

Effectiveness of Groups for Adolescents With Type 1 Diabetes Mellitus and Their Parents [PDF]

open access: yes, 2013
Peer- and family-based group therapies have been used as separate interventions to improve adjustment and self-management among youth with Type 1 diabetes mellitus.
Alemzadeh, Ramin   +4 more
core   +2 more sources

Genetics of type 1 diabetes mellitus [PDF]

open access: yesGenes & Immunity, 2002
At least 20 different chromosomal regions have been linked to type 1 diabetes (T1D) susceptibility in humans, using genome screening, candidate gene testing, and studies of human homologues of mouse susceptibility genes. The largest contribution from a single locus (IDDM1) comes from several genes located in the MHC complex on chromosome 6p21.3 ...
Michael F. McDermott, Flemming Pociot
openaire   +2 more sources

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

open access: yesFEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang   +7 more
wiley   +1 more source

Association of time in range with hemoglobin A1c, glycated albumin and 1,5‐anhydro‐d‐glucitol

open access: yesJournal of Diabetes Investigation, 2021
Aims/Introduction Hemoglobin A1c (HbA1c), glycated albumin (GA) and 1,5‐anhydro‐d‐glucitol (1,5‐AG) are used as indicators of glycemic control, whereas continuous glucose monitoring (CGM) is used to assess daily glucose profiles.
Mana Ohigashi   +10 more
doaj   +1 more source

Influence of diabetes on autonomic function in children: analysis through the geometr ic indices [PDF]

open access: yes, 2016
Introduction: Diabetes mellitus type 1 has been established as one of the most common noncommunicable diseases among children, diabetic autonomic dysfunction presenting as one of its most frequent complications, however, few studies have evaluated ...
Giacon, Thais Roque   +5 more
core   +2 more sources

Positive feedback loop between MAPK and aquaporin 7 regulates autophagy and apoptosis induced by palmitate in RIN‐m5f cells

open access: yesFEBS Open Bio, EarlyView.
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang   +5 more
wiley   +1 more source

Real life with type 1 diabetes mellitus

open access: yesIndian Journal of Endocrinology and Metabolism, 2015
Type 1 diabetes mellitus (T1DM) is a form of diabetes mellitus that results from the autoimmune destruction of the insulin-producing beta cells in the pancreas.
Deepak Yagnik
doaj   +1 more source

Gender-Based Comparative Study of Type 2 Diabetes Risk Factors in Kolkata, India: A Machine Learning Approach [PDF]

open access: yesarXiv, 2023
Type 2 diabetes mellitus represents a prevalent and widespread global health concern, necessitating a comprehensive assessment of its risk factors. This study aimed towards learning whether there is any differential impact of age, Lifestyle, BMI and Waist to height ratio on the risk of Type 2 diabetes mellitus in males and females in Kolkata, West ...
arxiv  

Immunogenetics of type 1 diabetes mellitus [PDF]

open access: yesMolecular Aspects of Medicine, 2015
Type 1 diabetes mellitus (T1DM) is an autoimmune disease arising through a complex interaction of both genetic and immunologic factors. Similar to the majority of autoimmune diseases, T1DM usually has a relapsing remitting disease course with autoantibody and T cellular responses to islet autoantigens, which precede the clinical onset of the disease ...
Michael P. Morran   +3 more
openaire   +2 more sources

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

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