Results 71 to 80 of about 2,069,350 (347)

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

The Impact of poor glycaemic control on the prevalence of erectile dysfunction in men with type 2 Diabetes Mellitus: A Systematic Review. [PDF]

, 2015
To determine the impact of poor glycaemic control on the prevalence of erectile dysfunction among men with type 2 Diabetics aged 27 to 85 years.The databases Embase classic+Embase, Global health, Ovid Medline and PsychINFO, were searched for relevant ...
Alsaad, S, Binmoammar, T, Hassounah, SOA, Majeed, A, Rawaf, S   +4 more
core   +1 more source

Glycogenic Hepatopathy in Type 1 Diabetes Mellitus

Case Reports in Hepatology, 2015
Glycogenic hepatopathy is a rare cause of high transaminase levels in type 1 diabetes mellitus. This condition, characterized by elevated liver enzymes and hepatomegaly, is caused by irreversible and excessive accumulation of glycogen in hepatocytes ...
Murat Atmaca, Rifki Ucler, Mehmet Kartal, Ismet Seven, Murat Alay, Irfan Bayram, Sehmus Olmez   +6 more
doaj   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Immunogenetics of type 1 diabetes mellitus [PDF]

Molecular Aspects of Medicine, 2015
Type 1 diabetes mellitus (T1DM) is an autoimmune disease arising through a complex interaction of both genetic and immunologic factors. Similar to the majority of autoimmune diseases, T1DM usually has a relapsing remitting disease course with autoantibody and T cellular responses to islet autoantigens, which precede the clinical onset of the disease ...
Michael P. Morran, Andrew Vonberg, Anmar Khadra, Massimo Pietropaolo   +3 more
openaire   +2 more sources

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao, Katherine R Schon, Jana Vandrovcova, Özlem Yayıcı Köken, Sharika Raga, Kireshnee Naidu, Maryke Schoonen, Nimita Rani, Pedro Tomaselli, Dipti Baskar, Musambo Kapapa, Ipek Polat, Lindsay A Wilson, Kumarasamy Thangaraj, Uluç Yiş, Bevinahalli N Nandeesh, David Bearden, Michelle Kvalsund, Franclo Henning, Seena Vengalil, Atchayaram Nalini, Claudia F. R. Sobreira, Wilson Marques, Haluk Topoloğlu, Michael G Hanna, Sireesha Yareeda, Venugopalan Y Vishnu, Francois H van der Westhuizen, Izelle Smuts, Surita Meldau, Jo Wilmshurst, Büşranur Çavdarlı, Jeannine Heckmann, Patrick F Chinnery, Rita Horvath   +34 more
wiley   +1 more source

Gender-Based Comparative Study of Type 2 Diabetes Risk Factors in Kolkata, India: A Machine Learning Approach [PDF]

arXiv, 2023
Type 2 diabetes mellitus represents a prevalent and widespread global health concern, necessitating a comprehensive assessment of its risk factors. This study aimed towards learning whether there is any differential impact of age, Lifestyle, BMI and Waist to height ratio on the risk of Type 2 diabetes mellitus in males and females in Kolkata, West ...
arxiv  

Real life with type 1 diabetes mellitus

Indian Journal of Endocrinology and Metabolism, 2015
Type 1 diabetes mellitus (T1DM) is a form of diabetes mellitus that results from the autoimmune destruction of the insulin-producing beta cells in the pancreas.
Deepak Yagnik
doaj   +1 more source

Diabetes in Malta : current findings and future trends [PDF]

, 2005
Diabetes is a considerable global problem. Recent projections suggest that at least 194 million people suffer from diabetes worldwide. The World Health Organization suggests this number will increase to 333 million by 2025.
Buttigieg, Sandra C., O'Donoghue, Cynthia R., Townsend Rocchiccioli, Judith   +2 more
core  

Cardiovascular disease in type 1 diabetes mellitus [PDF]

, 2008
O risco de doença arterial coronariana (DAC) nos pacientes com diabetes melito tipo 1 (DM1) é conhecido desde o final dos anos 1970, sendo atualmente a principal causa de mortalidade na população adulta com diabetes tipo 1 de longa duração.
BETTI, Roberto Tadeu Barcelos, FEITOSA, Alina Coutinho R., LERÁRIO, Antonio Carlos, RASSI, Nelson, WAJCHENBERG, Bernardo Léo   +4 more
core   +1 more source