Results 151 to 160 of about 30,954,665 (307)
Interleukin‐39 is a Prognostic Biomarker and Therapy Target for Sepsis
Advanced Science, EarlyView.Sepsis triggers a significant increase in IL‐39 production, with circulating levels markedly elevated and positively correlated with disease severity and poor clinical prognosis in sepsis patients. Mechanistically, macrophage‐derived IL‐39 activates the GP130 signaling pathway via a ligand‐receptor interaction, thereby fueling the pro‐inflammatory ...
Feng‐zhi Zhang +9 more
wiley +1 more source
AgriFood: Journal of Agricultural Products for Food, EarlyView.Heavy metal pollution reduces soil health and threatens food safety by entering plants; however, the use of nanoparticles, biofertilizers, and organic fertilizers such as biochar offers a promising strategy for improvement and sustainable agriculture. ABSTRACT Heavy metal (HM) pollution, resulting from human activities such as mining and the excessive ...
Sina Siavash Moghaddam +4 more
wiley +1 more source
Moderate alcohol consumption, adiponectin, inflammation and type 2 diabetes risk : prospective cohort studies and randomized crossover trials [PDF]
, 2010 Background: Moderate alcohol consumption has been associated with a lower risk of type 2 diabetes in various populations. However, the underlying mechanisms are not entirely clear.
Joosten, M.M.
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The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence
AgriFood: Journal of Agricultural Products for Food, EarlyView.Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John +4 more
wiley +1 more source
Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities
AGING MEDICINE, EarlyView.Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley +1 more source
Diabetes mellitus in pregnancy : a clinical and public health problem [PDF]
Diabetes is the most frequently encountered endocrine disorder in pregnancy and is associated with adverse outcomes. Despite the urgent need for interventions to improve the outcomes for pregnancies complicated with diabetes, and the consistent ...
Wahabi, Haifa A. A.
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Percepções das pessoas com diabetes mellitus acerca da doença e das complicações crônicas [PDF]
, 2014 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Enfermagem, Florianópolis, 2014.O diabetes mellitus traz mudanças importantes na vida das pessoas, pois requer cuidados ...
Campos, Thais Silva Pereira
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Impact of Acute Functional Decline on Frailty and Mortality in Acutely Hospitalized Older Persons
AGING MEDICINE, EarlyView.Older persons with acute functional decline are often severely frail. Male sex, cognitive impairment, diabetes mellitus type 2, cancer, hearing impairment, and nursing home living increase the risk of severe frailty or death and should be considered when person‐centered care is planned for hospitalized older people.
Ali Vahedi +5 more
wiley +1 more source
Expert Consensus on the Management of Obesity in Older Adults (2026 Edition)
AGING MEDICINE, EarlyView.This graphical abstract summarizes a safety‐first framework for managing obesity in older adults, with attention to age, functional status, comorbidities, and sarcopenia risk. Key assessments include BMI, waist measures, body fat percentage, skeletal muscle mass, and comprehensive geriatric evaluation. Management prioritizes reducing visceral fat while
Qi Pan, Lixin Guo
wiley +1 more source
Role of cytokines in the pathogenesis of type 1 diabetes [PDF]
, 1996 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.T lymphocytes and macrophages appear to play an important role in mediating ß-cell damage and causing Type 1 diabetes.
Hussain, Munther Jaffar
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