Results 41 to 50 of about 1,232,473 (312)

Effects of 16 genetic variants on fasting glucose and type 2 diabetes in South Asians : ADCY5 and GLIS3 variants may predispose to type 2 diabetes [PDF]

, 2011
Background: The Meta-Analysis of Glucose and Insulin related traits Consortium (MAGIC) recently identified 16 loci robustly associated with fasting glucose, some of which were also associated with type 2 diabetes.
Hydrie, MZI, Simon D. Rees, Abdul Basit, Hydrie M. Zafar I., Shera, A. Samad, Barnett, Anthony, Shera A. Samad, M. Zafar I. Hydrie, Basit, A, Basit Abdul, Anthony H Barnett, J. Paul O'Hare, Kumar Sudhesh, Sudhesh Kumar, Rees, Simon D., Rees, Simon, Kelly, M. Ann, Shera, AS, Kelly, Marilyn, A Samad Shera, Basit, Abdul, O'Hare J. Paul, Rees Simon D., J Paul O'Hare, A. Samad Shera, O'Hare, JP, Anthony H. Barnett, Kumar, Sudhesh, M. Ann Kelly, Kelly M. Ann, Hydrie, M. Zafar I., Simon D Rees, Barnett, A. H., Kumar, S, M Zafar I Hydrie, O'Hare, J. Paul, Barnett Anthony H., M Ann Kelly   +37 more
core   +1 more source

Dyslipidemia in Type 2 Diabetes Mellitus

Journal of Islamic International Medical College, 2021
Objective: To determine the correlation of plasma glucose levels with lipid profile in type 2 Diabetes Mellitus (T2DM). Study Design: Case control study.
Mehnaz Khattak, Asif Nawaz, Jawwad Anis Khan, Umme Farwa
doaj  

Simvastatin Use in Patients with Type 2 Diabetes Mellitus: The Effects on Oxidative Stress

Oman Medical Journal, 2015
Objectives: Studies have shown that people with type 2 diabetes mellitus (T2DM)may develop atherosclerosis due to the disturbance in oxidative control and progressive dyslipidemia.
Mohammad A. Abdelhussein, Ammar R. M. Rudha, Dina A. Jamil, Hayder A. Al-Aubaidy   +3 more
doaj   +1 more source

Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin [PDF]

, 2010
OBJECTIVE The aim of this study was to investigate whether apolipoprotein B100 of LDL suffers increased damage by glycation, oxidation, and nitration in patients with type 2 diabetes, including patients receiving metformin therapy.
Rabbani, Naila, D. Zehnder, A. Ceriello, P. J. Thornalley, N. Rabbani, Zehnder, Daniel, Chittari, Madhu Varma, C. W. Bodmer, Bodmer, Charles W., Ceriello, Antonio, M. V. Chittari, Thornalley, Paul J.   +11 more
core   +1 more source

Low birthweight is associated with type 2 diabetes mellitus in Japanese adults: The Toon Health Study

Journal of Diabetes Investigation, 2020
Aims/Introduction Low birthweight is reportedly associated with type 2 diabetes mellitus; however, this association has not been confirmed in the Japanese population, and whether high birthweight is associated with type 2 diabetes mellitus is ...
Maki Yokoyama, Isao Saito, Megumi Ueno, Hiroaki Kato, Ayaka Yoshida, Ryoichi Kawamura, Koutatsu Maruyama, Yasunori Takata, Haruhiko Osawa, Takeshi Tanigawa, Takashi Sugiyama   +10 more
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Type 2 diabetes mellitus and osteoarthritis

Seminars in Arthritis and Rheumatism, 2019
Type 2 diabetes mellitus (T2DM) and osteoarthritis (OA) are common diseases that frequently co-exist, along with overweight/obesity. While the mechanical impact of excess body weight on joints may explain lower limb OA, we sought to explore whether T2DM is linked to OA outside of excess weight and whether T2DM may play a role in OA pathophysiology. The
Veronese, Nicola, Cooper, Cyrus, Reginster, Jean-Yves, Hochberg, Marc, Branco, Jaime, Bruyère, Olivier, Chapurlat, Roland, Al-Daghri, Nasser, Dennison, Elaine, Herrero-Beaumont, Gabriel, Kaux, Jean-François, Maheu, Emmanuel, Rizzoli, Rene, Roth, Roland, Rovati, Lucio C., Uebelhart, Daniel, Vlaskovska, Mila, Scheen, André   +17 more
openaire   +8 more sources