Results 81 to 90 of about 1,232,473 (312)

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Changing paradigms in type 2 diabetes mellitus

Indian Journal of Endocrinology and Metabolism, 2013
Diabetes mellitus has been increasing in prevalence and imposes serious economic burdens on both the developed as well as the developing world. Understanding pathobiological underpinning of chronic progressive disease like diabetes is an imperative that ...
Romesh Khardori
doaj   +1 more source

Network-Level Structural Abnormalities of Cerebral Cortex in Type 1 Diabetes Mellitus [PDF]

, 2013
Type 1 diabetes mellitus (T1DM) usually begins in childhood and adolescence and causes lifelong damage to several major organs including the brain. Despite increasing evidence of T1DM-induced structural deficits in cortical regions implicated in higher ...
Hyeonseok S Jeong, Gail Musen, Hyeonseok S. Jeong (449823), In Kyoon Lyoo (399200), Weinger, K, Weinger Katie, Sujin Bae (279960), Jiyoung J. Jung (399196), Bolo, Nicolas, Bae, Sujin, Donald C. Simonson (297772), Bae, S, Lyoo In Kyoon, Lyoo, In Kyoon, Gail Musen (449820), Nicolas Bolo, Yoon, Sujung, Yera Choi (399197), Lyoo, IK, Jacobson, Alan M., Jieun E. Kim (449821), Ryan, CM, Simonson, Donald, Sujin Bae, Sujung Yoon (399194), Katie Weinger, Jeong Hyeonseok S., Simonson, Donald C., Christopher M. Ryan (410965), Hwang, J, Choi, Yera, Zuo, Xi-Nian, Kim Jieun E., Sujung Yoon, Bae Sujin, Bolo, N, Alan M Jacobson, Alan M. Jacobson (399199), Jeong, Hyeonseok S., Renshaw, PF, Jeong, HS, Sun Hea Lee (449824), Musen, G, Hwang Jaeuk, Simonson Donald C., Lee Sun Hea, Jacobson, AM, Lee, Sun Hea, Yera Choi, Perry F Renshaw, Ryan, Christopher M., Christopher M Ryan, Jung, JJ, Musen Gail, Jung Jiyoung J., In Kyoon Lyoo, Perry F. Renshaw (286262), Choi, Y, Renshaw, Perry F., Jiyoung J Jung, Hwang, Jaeuk, Kim, Jieun E., Yoon Sujung, Lee, SH, Jung, Jiyoung J., Weinger, Katie, Yoon, S, Kim, JE, Katie Weinger (449825), Choi Yera, Renshaw Perry F., Ryan Christopher M., Jacobson Alan M., Musen, Gail, Jaeuk Hwang, Donald C Simonson, Sun Hea Lee, Bolo Nicolas, Jieun E Kim, Jaeuk Hwang (449819), Nicolas Bolo (449822), Simonson, DC   +81 more
core   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Glomerulonephritis In Type 2 Diabetes Mellitus

Asian Journal of Health Sciences, 2013
Glomerulonephritis is also known as glomerular nephritis (GN) or glomerular disease. It is a disease of the kidney, characterized by inflammation of the glomeruli. The present study was undertaken with the objectives to explore the incidence and clinical profile of non diabetic renal disease in type 2 Diabetes Mellitus, to observe renal histology, to ...
Sanjeev Sanjeev, M.K. Mohan Das
openaire   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

Diabetes mellitus in patients with heart failure and effect modification of risk factors for short-term mortality: An observational study from the Registro Colombiano de Falla Cardíaca (RECOLFACA)

Biomédica: revista del Instituto Nacional de Salud
Introduction. Heart failure and type 2 diabetes mellitus are critical public health issues. Objective. To characterize the risk factors for mortality in patients with heart failure and type 2 diabetes mellitus from a large registry in Colombia and to ...
Luis Eduardo Echeverría, Clara Saldarriaga, Sebastián Campbell-Quintero, Lisbeth Natalia Morales-Rodríguez, Juan David López-Ponce de León, Andrés Felipe Buitrago, Erika Martínez-Carreño, Jorge Alberto Sandoval-Luna, Alexis Llamas, Gustavo Adolfo Moreno-Silgado, Julián Vanegas-Eljach, Nelson Eduardo Murillo-Benítez, Ricardo Gómez-Paláu, Alex Arnulfo Rivera-Toquica, Juan Esteban Gómez-Mesa, RECOLFACA research group   +15 more
doaj   +1 more source

Evidence review : liraglutide for the treatment of type 2 diabetes [PDF]

, 2011
This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of liraglutide in the treatment of type 2 diabetes mellitus, based upon the manufacturer’s submission to the National Institute
Cummins, E. (Ewen), Waugh, Norman, Shyangdan, D. (Deepson), Royle, Pamela, HASH(0x55a67fac50c0)   +4 more
core  

Pre-pregnancy care for women with pre-gestational diabetes mellitus : a systematic review and meta-analysis [PDF]

, 2012
Background Pre-gestational diabetes mellitus is associated with increased risk for maternal and fetal adverse outcomes. This systematic review was carried out to evaluate the effectiveness and safety of pre-pregnancy care in improving the rate of ...
Samia A Esmaeil, Wahabi, Haifa A. A., Alzeidan, Rasmieh A., Hayfaa A Wahabi, Esmaeil, Samia A., Rasmieh A Alzeidan   +5 more
core   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source