Results 81 to 90 of about 2,504,313 (305)
The interim experts’ counsil resolution on the EMPA-REG OUTCOME trial issues
The interdisciplinary interim experts’ counsil on March 3, 2016 in Moscow have considered the EMPA-REG OUTCOME trial results and suggested a number of prorositions and remommendations on further empagliflozin’s cardiovascular effects ...
Editorial team Diabetes Mellitus
doaj +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
The anti-atherogenic effects of thiazolidinediones [PDF]
The thiazolidinediones (TZDs) rosiglitazone (ROS) and pioglitazone (PIO) are insulin-sensitising agents widely used to treat patients with type 2 diabetes mellitus (T2DM). Thiazolidinediones significantly improve glycaemic control in diabetics by reduced
Honisett, Suzy +2 more
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Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
Perbedaan Kadarkolesterol Pada Pasien Diabetes Melitus Tipe II Yang Disertai Hipertensi Dengan Tanpa Hipertensi Di RSUD Sukoharjo [PDF]
Background: Indonesia that number 4 ranking as the country with the highest number of people with diabetes mellitus in the world according to the WHO.
, dr. Listiana Masyita Dewi, M.Sc +2 more
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The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon +21 more
wiley +1 more source
ScRNA‐seq reveals ZFPL1‐specific enrichment in malignant CRC cells. Mechanistically, ZFPL1 stabilizes ASS1 by blocking K57 ubiquitination, activating urea cycle metabolism to drive progression. ZFPL1 inhibition reprograms the TME by suppressing M2 macrophages polarization and promotion M1 macrophages, thereby inhibiting CRC liver metastasis ...
Xiangjun Qian +14 more
wiley +1 more source
Hospitalization causes due to iron overload in beta-Thalassemia in Gorgan, Iran [PDF]
Objective: To evaluate causes of hospitalization (due to complications of iron overload and other causes) in beta-Thalassemic patients. Methodology: This study was performed on 244 patients with major beta-Thalassemia admitted in Taleghani hospital of ...
Jahazi, A. +2 more
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Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun +16 more
wiley +1 more source
HUBUNGAN KECEMASAN DENGAN KADAR HbA1c PADA PASIEN DIABETES MELITUS TIPE 2 DI RSUD KARANGANYAR [PDF]
Reza Satria HS, G0012178, 2015. Correlation between Anxiety and HbA1c Level among Diabetes Mellitus Type 2 Patients in RSUD Karanganyar. Mini Thesis, Faculty of Medicine, Sebelas Maret University, Surakarta.
Satria HS, Reza
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