Results 81 to 90 of about 917,880 (323)

Advancing Chronic Wound Healing through Electrical Stimulation and Adipose‐Derived Stem Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Chronic cutaneous wounds represent significant challenges due to delayed healing and resistance to conventional treatments. This review explores the potential of combining adipose‐derived stem cells with electrical stimulation to enhance wound healing.
Qiuyue Peng   +5 more
wiley   +1 more source

Association between serum haptoglobin and carotid arterial functions: usefulness of a targeted metabolomics approach

open access: yesCardiovascular Diabetology, 2019
Background Serum haptoglobin (Hp) has been closely associated with cardio-cerebrovascular diseases. We investigated a metabolic profile associated with circulating Hp and carotid arterial functions via a targeted metabolomics approach to provide insight ...
Shiyun Wang   +9 more
doaj   +1 more source

Fenugreek : a natural prototype oral hypoglycaemic agent used in Malta [PDF]

open access: yes, 2009
Before the discovery of insulin therapy in 1921 and the development of effective oral hypoglycaemic therapy in 1926, pharmacological management of diabetes mellitus was restricted to empirical treatment often based on plant products and relegated to ...
Savona-Ventura, Charles
core  

Lycium‐Barbarum Polysaccharide‐Loaded Dual‐Crosslinked Rigid Hydrogel Enhances Bone Healing in Diabetic Bone Defects by Scavenging Reactive Oxygen Species

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel hydrogel (HLBP) incorporating natural polysaccharides from goji berries is developed to enhance diabetic bone defect healing. The hydrogel efficiently scavenges ROS, improves osteogenic differentiation, and promotes in vivo bone regeneration. This strategy offers a biocompatible and localized approach, overcoming the challenges of traditional ...
Wenjie Zhong   +9 more
wiley   +1 more source

The chloride/phosphate ratio combined with alkaline phosphatase as a valuable predictive marker for primary hyperparathyroidism in Chinese individuals

open access: yesScientific Reports, 2017
The chloride/phosphate ratio (Cl/PO4) has been suggested to have a role in primary hyperparathyroidism (PHPT), but the associations between Cl/PO4 combined with ALP level and PHPT has not been well-studied. Our aim was to investigate the predictive value
Qianqian Wang   +13 more
doaj   +1 more source

Risk Factors of Diabetes Mellitus in Rural Puducherry [PDF]

open access: yes, 2012
Purpose: Prevalence of type 2 diabetes is increasing in India. Rural area constitutes 80% of India. Hence it is essential to understand the epidemiology for appropriate interventions.
Das, AK   +3 more
core   +1 more source

Self‐Healing Hydrogel Dressing with Solubilized Flavonoids for Whole Layer Regeneration of Diabetic Wound

open access: yesAdvanced Healthcare Materials, EarlyView.
High glucose‐ and acid‐responsive hydrogel with dynamic covalent bond solubilized with flavonoids (Gel‐Flavonoids) is designed for diabetic wound healing. The Gel‐Flavonoids adapt to irregular wound shapes and release antioxidants in high‐glucose environments, effectively reducing reactive oxygen species.
Qiang Zeng   +9 more
wiley   +1 more source

Accelerated Bone Healing via Electrical Stimulation

open access: yesAdvanced Science, EarlyView.
Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun   +4 more
wiley   +1 more source

The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ

open access: yesAdvanced Science, EarlyView.
The placenta expresses much higher levels of PPARγ than fetal adipose tissue. Trophoblastic exosomes transport PPARγ into fetal preadipocytes via fetoplacental circulation and thus regulate adipogenic genes distinct from endogenous PPARγ. Compromised placental PPARγ leads to fetal adipogenesis deficiency and intrauterine growth restriction, reversible ...
Xiaofang Luo   +17 more
wiley   +1 more source

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