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Type 1 diabetes mellitus as a disease of the β-cell (do not blame the immune system?)

open access: yesNature Reviews Endocrinology, 2020
Type 1 diabetes mellitus is believed to result from destruction of the insulin-producing β-cells in pancreatic islets that is mediated by autoimmune mechanisms. The classic view is that autoreactive T cells mistakenly destroy healthy (‘innocent’) β-cells.
B. Roep   +3 more
semanticscholar   +1 more source

Vitamin D e diabetes melito: uma atualização 2013 [PDF]

open access: yes, 2014
Vitamin D deficiency and diabetes mellitus are two common conditions and they are widely prevalent across all ages, races, geographical regions, and socioeconomic conditions.
Bandeira, Francisco   +4 more
core   +3 more sources

Loeys-Dietz Syndrome with Type 1 Diabetes Mellitus

open access: yesClinical Pediatric Hematology-Oncology, 2023
Loeys-Dietz syndrome is a hereditary connective-tissue disorder first reported in 2005. It is caused by genetic defects in the transforming growth factor-beta (TGF-β) signaling pathway.
Daro Jeong, Jung Hyun Lee, Seom Gim Kong
doaj   +1 more source

Cardiovascular risk in type 1 diabetes mellitus

open access: yesIndian Journal of Endocrinology and Metabolism, 2013
Commonly cardiovascular risk (CVR) is linked to type 2 diabetes mellitus as this type is known to be part of the metabolic syndrome, which includes other cardiovascular factors such as hypertension, dyslipidemia.
Ines Ben Hadj Slama Slim
doaj   +1 more source

Association of high-sensitive C-reactive protein with advanced stage beta-cell dysfunction and insulin resistance in patients with type 2 diabetes mellitus [PDF]

open access: yes, 2006
Background: Type 2 diabetes mellitus is associated with increased cardiovascular risk. One laboratory marker for cardiovascular risk assessment is high-sensitivity C-reactive protein (hsCRP).
Balkau   +33 more
core   +1 more source

Human islet isolation and allotransplantation in 22 consecutive cases [PDF]

open access: yes, 1992
This report provides our initial experience in islet isolation and intrahepatic allotransplantation in 21 patients. In group 1, 10 patients underwent combined liver-islet allotransplantation following upper-abdominal exenteration for cancer.
Alejandro, R   +10 more
core   +1 more source

Bone remodeling in type 1 diabetes mellitus

open access: yesБюллетень сибирской медицины, 2018
The aim of the study is to assess the effect of changes in the body in men and women with type 1 diabetes on the state of bone mineral density and metabolic rate and determine the directionality of changes in serum markers of bone remodeling and bone ...
S. S. Safarova
doaj   +1 more source

Circulating microRNAs as novel biomarkers for diabetes mellitus. [PDF]

open access: yes, 2013
Diabetes mellitus is characterized by insulin secretion from pancreatic β cells that is insufficient to maintain blood glucose homeostasis. Autoimmune destruction of β cells results in type 1 diabetes mellitus, whereas conditions that reduce insulin ...
A Caporali   +101 more
core   +1 more source

Type 1 diabetes in India: Overall insights

open access: yesIndian Journal of Endocrinology and Metabolism, 2015
Type 1 diabetes mellitus (T1DM) is also on increase like type 2 diabetes, even though not in the same proportion, but still with a trend of 3-5% increase/year. India has three new cases of T1DM/100,000 children of 0-14 years.
Ashok Kumar Das
doaj   +1 more source

Association of time in range with hemoglobin A1c, glycated albumin and 1,5‐anhydro‐d‐glucitol

open access: yesJournal of Diabetes Investigation, 2021
Aims/Introduction Hemoglobin A1c (HbA1c), glycated albumin (GA) and 1,5‐anhydro‐d‐glucitol (1,5‐AG) are used as indicators of glycemic control, whereas continuous glucose monitoring (CGM) is used to assess daily glucose profiles.
Mana Ohigashi   +10 more
doaj   +1 more source

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