Results 141 to 150 of about 1,638,165 (347)

Perbandingan Pendidikan Kesehatan Antara Metode Diskusi Dan Pemecahan Masalah Dalam Perubahan Perilaku Pasien Diabetes Melitus Tipe 2 Di RSUD Swadana Pekalongan [PDF]

open access: yes, 2007
Forty-five percents of 2.4 millions diabetes mellitus patients in Indonesia could not be treated well because of noncompliance to the treatment. One of the reasons of this noncompliance was the lack of understanding about diabetes mellitus disease.
Haryati, W. (Welas)   +1 more
core  

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

open access: yesAdvanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li   +8 more
wiley   +1 more source

Self-consciousness of type 2 diabetes mellitus patients

open access: yesHealthcare in Low-resource Settings
The characteristics of self-consciousness of people with diabetes mellitus are determined by knowledge about diabetes mellitus, the signs and symptoms of acute and chronic complications, and the side effects of diabetes treatment.
Dikha Ayu Kurnia   +4 more
doaj   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

open access: yesAdvanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen   +12 more
wiley   +1 more source

Predicting diabetes management self-efficacy base on hardiness and coping strategies in patients with type 2 diabetes mellitus [PDF]

open access: yes, 2016
Background: Stress and negative emotions has a role in prediction type 2 diabetes mellitus and Self- efficacy effectiveness on commitment to self- management behaviors.
Ghodrati Mirkohi, M, Rahimian Boogar, I
core  

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan   +11 more
wiley   +1 more source

HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration

open access: yesAdvanced Science, EarlyView.
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong   +14 more
wiley   +1 more source

A Novel CYP2E1 Inhibitor, 4‐Methyl‐5‐Acetylthiazole (Q11), Alleviates Obesity Via Modulating Adipose Inflammation and Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
Obesity involves chronic inflammation and mitochondrial dysfunction. This study identifies cytochrome P450 2E1 (CYP2E1) as a novel inflammatory target in adipose tissue. Its activity increases in obese mice and correlates with inflammation and mitochondrial impairment.
Jinhuan Qiu   +10 more
wiley   +1 more source

Betatrophin in type 2 diabetes mellitus

open access: yesJournal of Mahatma Gandhi Institute of Medical Sciences, 2013
Omprakash Gupta
doaj   +1 more source

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