Results 241 to 250 of about 536,995 (305)

Drug Coated Balloons Versus Drug‐Eluting Stents in Patients With De Novo Coronary Artery Disease

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background In patients with de novo coronary artery disease (CAD), percutaneous coronary intervention (PCI) with drug eluting stent (DES) implantation is the gold standard therapy. New evidence is available with drug coated balloons (DCB) angioplasty. The objective of this meta‐analysis was to compare the efficacy and safety of DCB angioplasty
Daniel O'Callaghan   +9 more
wiley   +1 more source

Navigating the Uncertainties of Antithrombotic Therapy After Transcatheter Patent Foramen Ovale Closure: A Comprehensive Review

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT The patent foramen ovale (PFO), present in 25% of the population, can cause paradoxical embolism and stroke. Transcatheter PFO closure is the gold standard for recurrent embolism with significant inter‐atrial shunting, with recent trials confirming its superiority in reducing ischemic stroke recurrence over medical therapy.
Eirini Beneki   +13 more
wiley   +1 more source

Cost‐Utility Analysis of Different Treatment Modalities in Patients Undergoing Percutaneous Coronary Intervention: Thai PCI Registry

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Cost‐utility analyses of percutaneous coronary interventions (PCIs) provide valuable insights into the economic value of these procedures. However, data is lacking, particularly in developing countries with limited resources. Aims This analysis aimed to compare the cost‐utility of different treatment modalities used for PCI patients
Oraluck Pattanaprateep   +5 more
wiley   +1 more source

Green tea and type 2 diabetes mellitus [PDF]

open access: yesJournal of Nephropharmacology, 2014
Rafieian-Kopaei Mahmoud   +8 more
doaj  

Protocol for an Integrative Meta‐Analysis of the Application of Machine Learning Algorithms in the Prediction of Chronic Disease Risks and Outcomes

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Background Precise risk prediction of chronic diseases is essential for effective preventive care and management. Machine learning (ML) is a promising avenue to enhance chronic disease risk prediction; however, a comprehensive assessment of ML performance across various chronic diseases, populations, and health settings is needed. Methods This
Ebenezer Afrifa‐Yamoah   +4 more
wiley   +1 more source

HDL‐C/LDL‐C Ratio and All‐Cause Mortality in Populations at High CVD Risk: A Prospective Observational Cohort Study

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Background The ratio of high‐density lipoprotein cholesterol (HDL‐C) to low‐density lipoprotein cholesterol (LDL‐C) predicts cardiovascular disease (CVD) endpoints, yet its prognostic validity in high‐risk populations and for type 2 diabetes mellitus (T2DM)‐related adverse events remains unestablished. Methods This study included 32,609 people
Biting Lin   +10 more
wiley   +1 more source

Considerations in Transition of Pediatric Neurology Patients to Adult Care

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Background Transition refers to the planned, coordinated movement of adolescents from the child‐ and family‐centered environment of pediatric care to the adult healthcare system. A well‐structured transition process is essential for ensuring adolescents with chronic health conditions continue to thrive in young adulthood.
Asif Doja   +5 more
wiley   +1 more source

Pharmacokinetic and Bioequivalence Evaluation of Two Sitagliptin Tablets With Different Salts in Healthy Subjects

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract The objective of the current study was to evaluate the rate and extent of absorption of a test formulation (sitagliptin hydrochloride) and a reference formulation (sitagliptin phosphate). An open‐label, randomized, single‐dose, single‐center, 2‐sequence, 2‐period, and cross‐over phase 1 study was implemented to assess the pharmacokinetic ...
Usok Hyun   +7 more
wiley   +1 more source

A Pharmacometric Method for Quantitative Determination of Improvement in Body Composition and Characterization of the Exposure–Response Relationship during Treatment of Obesity with Tirzepatide

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
About half of the world's population is living with overweight or obesity. Tirzepatide is an approved treatment for chronic weight management. We sought to characterize the exposure–response relationship for weight reduction in patients with overweight or obesity and quantify the associated changes in body composition.
Emmanuel Chigutsa   +4 more
wiley   +1 more source

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