Results 51 to 60 of about 4,355 (236)

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Arterial involvement of lower limbs in peripheral artery disease - the difference between diabetics and non-diabetics

Journal of the Pakistan Medical Association
Objective: To detect peripheral artery disease in diabetic and non-diabetic individuals. Method: The case-control study was conducted from October 2018 to September 2019 at Ruth K.M.
Tanzeela Khan, Naheed Khan, Sajida Qureshi   +2 more
doaj   +1 more source

EFFECT OF COMPLEX HOMEOPATHIC DRUG CONTAINING COENZYME Q ON PARAMETERS OF OXIDATIVE STRESS AND HEMODYNAMICS IN EXPERIMANTAL DIABETES MELLITUS

Рациональная фармакотерапия в кардиологии, 2016
Aim. To study the influence of complex homeopathic drug ubichinon compositum on hemodynamics, Na,K-ATPase activity, parameters of oxidative stress and serum nitric oxide (NO) metabolites concentration in experimental diabetes mellitus.Materials and ...
S. G. Dzugkoev, V. A. Metelskaya, I. V. Mozhaeva, F. S. Dzugkoeva   +3 more
doaj   +1 more source

Late‐onset epilepsy of unknown etiology is more treatment‐responsive than acquired lesional late‐onset epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Late‐onset epilepsy of unknown etiology (LOEU) carries an elevated risk of dementia, suggesting that it may represent an early manifestation of neurodegenerative or cerebrovascular disease. Direct comparisons between LOEU and acquired lesional late‐onset epilepsy (LOE) may elucidate clinical features specific to LOEU.
L. Brian Hickman, Bhavya Pandey, Alexander Fish, Mohit Bandla, Adnan Husein, Corinne Allas, Harika Kottakota, Lauren Herzog, Keith Vossel, John M. Stern   +9 more
wiley   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

Clinical decision support software for diabetic foot risk stratification: development and formative evaluation

Journal of Foot and Ankle Research, 2015
Background Identifying people at risk of developing diabetic foot complications is a vital step in prevention programs in primary healthcare settings. Diabetic foot risk stratification systems predict foot ulceration. The aim of this study was to explore
Deborah E. Schoen, David G. Glance, Sandra C. Thompson   +2 more
doaj   +1 more source

Expression of prostacyclin-stimulating factor (PSF) in mononuclear cells of human peripheral blood and THP-1 derived macrophage-like cells, and effects of high glucose concentration [PDF]

Prostacyclin (PGI2) synthesis by vascular endothelial cells (ECs) decreases in diabetic subjects, possibly leading to development of diabetic angiopathies including that in atherosclerosis.
Etoh, Takashi, Hashimoto, Toshihiko, Imamura, Minako, Inoguchi, Toyoshi, Nawata, Hajime, Sekiguchi, Naotaka   +5 more
core   +1 more source

Pathogenetic Role of Disorders of Insulin Signaling Pathways and Diabetes-Associated Hyperglycemia in the Mechanisms of Diabetic Encephalopathy Formation and Hypersensitivity of the Brain to Ischemia-Reperfusion [PDF]

, 2022
The aim of the study was to analyze the literature data regarding the pathogenetic role of insulin signaling disorders and diabetes-associated hyperglycemia in the mechanisms of diabetic encephalopathy and hypersensitivity of the brain to ischemia ...
Hodovanets, Yuliya, Nika, Olha, Tkachuk, Oleksiy, Tkachuk, Svitlana   +3 more
core   +2 more sources

Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov, Natalie Reitz, Marley Dewey, Colin L. Hisey   +3 more
wiley   +1 more source

Alzheimer's disease and mixed pathologies as a hidden contributor to fatal hypothermia: A large‐scale forensic autopsy‐based study

Brain Pathology, EarlyView.
We investigated neuropathological manifestations of hypothermia in 168 cases. Patients aged 65 years or more constituted 80% of the total cohort. Alzheimer's disease was the most common comorbidity, affecting 40% of all patients. Abstract There is a paucity of autopsy‐based studies providing detailed neuropathological characteristics of fatal ...
Shojiro Ichimata, Koji Yoshida, Ryo Tanaka   +2 more
wiley   +1 more source