Results 121 to 130 of about 78,086 (312)
Advanced Science, EarlyView.The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian +9 more
wiley +1 more source
Advanced Science, EarlyView.A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo +5 more
wiley +1 more source
An In-Shoe Laser Doppler Sensor for Assessing Plantar Blood Flow in the Diabetic Foot
An in-shoe laser Doppler sensor for assessing plantar blood flow in the diabetic foot. Jonathan Edwin Cobb Plantar ulceration is a complication of the diabetic foot prevalent in adults with type 11 diabetes mellitus.
Cobb, Jonathan E.
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Diabetic Foot Ulceration Education and Prevention in the Primary Care Setting
, 2019 Background and Purpose: Diabetes mellitus is associated with a series of macro and microvascular alterations that are associated with a number of complications.
Shelby, Tyler
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Advanced Science, EarlyView.A hybrid biomechanical–electromagnetic energy‐harvesting e‐skin is developed using a gelatin‐based outer matrix with a zwitterionic conductive inner layer. The e‐skin autonomously generates stable electrical stimulation from daily body motion and ambient electronics, enabling significantly enhanced wound healing bothin vitro and in vivo.
Syun‐Hong Chou +12 more
wiley +1 more source
Decision trees to facilitate risk stratification of the diabetic foot
, 2019 Aim: Delays in referrals from primary care to specialist care clinics are a common issue in the clinical management of diabetic foot disease and are associated with worse clinical outcomes in terms of ulcer healing and major amputations (1-3).
Jarl, Gustav,
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Assessment and management of diabetic ulcers in the primary health care setting [PDF]
, 2008 John is a 62 year old gentleman who has been suffering from type 2 Diabetes Mellitus for the past 7 years. He presents to the clinic with an ulcer 5 mm in diameter on the lateral aspect of the right foot near the metatarsophalangeal joint area. The ulcer
De Gabriele, Renzo
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Advanced Science, EarlyView.A periosteum‐inspired Janus piezoelectric scaffold converts micromechanical forces into electrical signals and synergizes with controlled resveratrol release. This dual action reprograms endothelial metabolism, drives H‑type vessel formation, and restores bone–vessel coupling in diabetic bone defects.
Kai Wang, Kai Jiang
wiley +1 more source
Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy
Advanced Science, EarlyView.A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao +11 more
wiley +1 more source