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Diabetes is reaching epidemic proportions and with it carries the risk of complications. Disease of the foot is among one of the most feared complications of diabetes. The ultimate endpoint of diabetic foot disease is amputation, which is associated with significant morbidity and mortality, besides having immense social, psychological and financial ...
Jeffrey W. Stephens+2 more
openaire +3 more sources
The association of chronic, enhanced immunosuppression with outcomes of diabetic foot infections
We investigated if a chronic, enhanced immunosuppressed condition, beyond the immunodeficiency related to diabetes, is associated with clinical failures after combined surgical and medical treatment for diabetic foot infection (DFI).
Ilker Uçkay+6 more
doaj +1 more source
Quantifying the Effect of Image Similarity on Diabetic Foot Ulcer Classification [PDF]
This research conducts an investigation on the effect of visually similar images within a publicly available diabetic foot ulcer dataset when training deep learning classification networks. The presence of binary-identical duplicate images in datasets used to train deep learning algorithms is a well known issue that can introduce unwanted bias which ...
arxiv +1 more source
An atypical and bilateral presentation of Charcot foot disease
Background Charcot neuropathic osteoarthropathy (CNO) is one of the most devastating complications of neuropathy in patients with diabetes. Establishing diagnosis of CNO is difficult, due to the lack of clear clinical and radiological diagnostic criteria.
C. V. Loupa+4 more
doaj +1 more source
The Charcot Foot in Diabetes [PDF]
The diabetic Charcot foot syndrome is a serious and potentially limb-threatening lower-extremity complication of diabetes. First described in 1883, this enigmatic condition continues to challenge even the most experienced practitioners. Now considered an inflammatory syndrome, the diabetic Charcot foot is characterized by varying degrees of bone and ...
Rogers, Lee C.+23 more
openaire +7 more sources
Background Recurrence after the healing of a foot ulcer is very common among patients with diabetes mellitus. Novel diabetic therapeutic footwear consisted of merino wool, vibration chip, and orthopedic insoles is designed to influence multifaceted ...
Yun Gao+12 more
doaj +1 more source
Role of M1 macrophages in diabetic foot ulcers and related immune regulatory mechanisms
Objectives: Diabetes foot ulcers (DFUs) are characterized by immune infiltration of M1 macrophages observed in foot skin, in which immune-associated genes (IRGs) play a prominent role.
Yao Li+18 more
doaj +1 more source
Diabetic foot syndrome is a complex set of anatomical and functional changes that occur in 30-60% of diabetic patients. A high content of glucose in the blood reduces its fluidity, capillary circulation and cell nutrition worsen. Such a state of blood for a long time leads to damage to the vessels and nerves of the lower extremities, to the disorder of
openaire +1 more source
Background Diabetic foot ulcer (DFU) is a common complication in patients with diabetes mellitus (DM) and can consequently lead to soft tissue infection and osteomyelitis.
C. V. Loupa+5 more
doaj +1 more source
Bacterial Diversity and Antibiotic Resistance in Patients with Diabetic Foot Osteomyelitis
This study analysed the bacterial diversity, antibiotic susceptibility, and resistance in patients with complications of diabetic foot osteomyelitis (DFO).
Francisco Javier Álvaro-Afonso+5 more
doaj +1 more source