Results 61 to 70 of about 44,427 (283)

Human Wounds and Its Burden: An Updated Compendium of Estimates [PDF]

, 2019
Significance: A 2018 retrospective analysis of Medicare beneficiaries identified that ∼8.2 million people had wounds with or without infections. Medicare cost estimates for acute and chronic wound treatments ranged from $28.1 billion to $96.8 billion ...
Sen, Chandan K.
core   +1 more source

NIR‐Activated Ag2S Quantum Dots for Efficient Broad‐Spectrum Antibacterial and Biofilm Disruption

Advanced Materials Interfaces, EarlyView.
This study presents a novel non‐antibiotic strategy leveraging NIR‐activated Ag2S QDs for synergistic PTT/PDT. The platform degrades the protective extracellular matrix via localized hyperthermia, facilitating deep penetration and ROS‐induced oxidative damage.
Rui Yao, Peiqing Sun, Yaxin Chen, Zhijie Lei, Li Wang, Jianglin Yu, Ying Liu, Wusimanjiang Hailipitimu, Wei Wei, Jing Zhao, Xusheng Qiu   +10 more
wiley   +1 more source

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

Advanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu, Yi Wan, Wenhao Shi, Bin Li, Haiyue Zhang, Jun Wu, Lingling Li, Wenjia Guo, Chen Ding, Wenjun Yang   +9 more
wiley   +1 more source

Prevalence of Diabetic Foot Ulcer and Determinant Factors Among Adult Diabetic Patients Who Attend the Diabetic Follow‐Up at Adwa General Hospital, Ethiopia, 2019: A Cross‐Sectional Study

Health Science Reports
Background and Aims Diabetic foot ulcers are the main complication of diabetes mellitus. There is limited information on the prevalence and factors of diabetic foot ulcers in Ethiopia, particularly to the study setting.
Haftea Hagos Mekonen, Tsegu Hailu Gebru
doaj   +1 more source

Virtually optimized insoles for offloading the diabetic foot: a randomized crossover study [PDF]

, 2017
Integration of objective biomechanical measures of foot function into the design process for insoles has been shown to provide enhanced plantar tissue protection for individuals at-risk of plantar ulceration.
Cavanagh, P.R., Collier, A., Telfer, S., Woodburn, J.   +3 more
core   +1 more source

Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

Advanced Science, EarlyView.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai, Siying Cheng, Fengguang Ma, Xiaorong Zhang, Jianan Huang, Zhonghua Liu, Bing Hu   +6 more
wiley   +1 more source

Pixel classification for automated diabetic foot diagnosis [PDF]

, 2009
Worldwide, more than 180 million people suffer from diabetes mellitus. Approximately 50% of these patients will develop complications to their feet. Neuropathy, combined with poor blood supply and biomechanical changes results in a high risk for foot ...
Baal, J.G. van, Bus, S.A., Hazenberg, S., Heijden, F. van der, Klein, A., Kloeze, C.   +5 more
core   +1 more source

Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts

Advanced Science, EarlyView.
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang, Jiaming Sun, Ying Wang, Bichen Ren, Yuxin Liu, Yunhan Liu, Liang Chen, Lu Yu, Tao Dai, Li Yu, Zhihui Dong   +10 more
wiley   +1 more source

The Effect of Vacuum Compression Therapy on Diabetic Foot ulcer

مجله پژوهش در علوم توانبخشی, 2008
• Background:Recent studies indicate that vacuum compression therapy (VCT) of the foot may offer benefits in patients with intermittent claudication through improving arterial and venous blood flow.
Mojtaba Heshmatipour, Vajiheh Abroshan, Azam Masihi   +2 more
doaj   +1 more source

A systematic review of cost-effectiveness analyses of complex wound interventions reveals optimal treatments for specific wound types. [PDF]

, 2015
BackgroundComplex wounds present a substantial economic burden on healthcare systems, costing billions of dollars annually in North America alone.
Antony, Jesmin, Cogo, Elise, Hoch, Jeffrey S, Isaranuwatchai, Wanrudee, Khan, Paul A, Sanmugalingham, Geetha, Straus, Sharon E, Tricco, Andrea C   +7 more
core   +3 more sources