Results 71 to 80 of about 44,427 (283)

Mitochondrial CircRNA CircMT‐RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair

Advanced Science, EarlyView.
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu, Jennifer Geara, Yongjian Chen, Lihua Luo, Yanwei Xiao, Zhuang Liu, Margaux Gaborieau, Ling Pan, Edmund Loh, Dongqing Li, Pehr Sommar, Aoxue Wang, Xiaowei Zheng, Ning Xu Landén   +13 more
wiley   +1 more source

The Economic Impact of Lower Extremity Amputations in Diabetics. a Retrospective Study From a Tertiary Care Hospital of Faisalabad, Pakistan [PDF]

, 2020
Background: Among the various complications of diabetes, lower-extremity amputation due to diabetic foot is a common problem. In Pakistan, 6-7% of patients with diabetes suffer from diabetic foot ulceration.
Ehsan, S. B. (Sumera), Labeeq, M. (Muhammad), Rehman, W. (Waleed), Tariq, M. A. (Muhammad), Tung, S. A. (Samra), Yar, M. A. (Muhammad)   +5 more
core  

Predictors of outcomes in diabetic foot osteomyelitis treated initially with conservative (nonsurgical) medical management: A retrospective study [PDF]

, 2016
The optimal way to manage diabetic foot osteomyelitis remains uncertain, with debate in the literature as to whether it should be managed conservatively (ie, nonsurgically) or surgically. We aimed to identify clinical variables that influence outcomes of
Catherine Gooday, Heiba S, Ian Nunney, Ketan Dhatariya, Paul Zeun, van der Meer JW   +5 more
core   +1 more source

Periodontitis Induces B Cell‐Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity

Advanced Science, EarlyView.
In obesity, periodontitis exacerbates hyperglycemia and exhibits a liver‐centric preference for glucose regulation. This occurs through a periodontitis‐driven circuit between pathogenic B cells and hepatic macrophages. Their reciprocal expansion, orchestrated by the NLRP3/IL‐18 signaling pathway, amplifies metabolic inflammation and disrupts glucose ...
Wen‐Zhen Lin, Lu‐Jun Zhou, Hui‐Lin Ye, Ting Liu, Bo‐Yan Chen, Xue‐Bing Bai, Jun Zhang, Lan Bai, Lin‐Juan Du, Yuan Liu, Yong‐Li Wang, Hong Zhu, Yu‐Lin Li, Shuo Xu, Xiao‐Qian Meng, Guo‐Cai Tian, Yan Liu, Wu‐Chang Zhang, Ya‐Qin Zhu, Sheng‐Zhong Duan   +19 more
wiley   +1 more source

Diabetic Foot Ulcer

GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh
Ulkus diabetikum adalah luka yang terbuka pada permukaan kulit sebagai komplikasi makroangiopati dan mikroangiopati. Sebanyak 15-25% pasien diabetes melitus (DM) diperkirakan dapat mengalami komplikasi ulkus kaki diabetik dalam masa hidupnya. Pasien laki-laki 58 tahun datang dengan keluhan luka pada kaki kiri yang dirasakan sejak 3 minggu ini.
Fakhrizal Fakhrizal, Elvina Moulidiya
openaire   +2 more sources

Research progress of triglyceride-glucose index with type 2 diabetes mellitus and diabetic foot ulcer

Zhongguo linchuang yanjiu
Diabetic foot ulcer is a serious complication of diabetes mellitus, usually caused by neuropathy and peripheral arterial disease. Studies have shown that insulin resistance is a known risk factor for diabetic foot ulcer.
SHEN Xinyi, LIU Qingyang
doaj   +1 more source

A study of risk factors and foot care behavior among diabetics

Journal of Family Medicine and Primary Care, 2016
Background: Diabetic foot results in considerable morbidity and mortality in developing countries and the prevalence of diabetes is expected to increase further in the next decades in these countries.
Mackson Nongmaithem, Arjinder Pal Singh Bawa, Abhilash Kumar Pithwa, Simran Kaur Bhatia, Gurjit Singh, Somnath Gooptu   +5 more
doaj   +1 more source

Effects of novel diabetic therapeutic footwear on preventing ulcer recurrence in patients with a history of diabetic foot ulceration: study protocol for an open-label, randomized, controlled trial

Trials, 2021
Background Recurrence after the healing of a foot ulcer is very common among patients with diabetes mellitus. Novel diabetic therapeutic footwear consisted of merino wool, vibration chip, and orthopedic insoles is designed to influence multifaceted ...
Yun Gao, Chun Wang, Dawei Chen, Hui Huang, Lihong Chen, Guanjian Liu, Shuang Lin, Min Liu, Xiaorong Wen, Jae-Hoon Cho, Yong Chen, Yingzhu Li, Xingwu Ran   +12 more
doaj   +1 more source

Self-reported use of complementary and alternative medicine (CAM) products in topical treatment of diabetic foot disorders by diabetic patients in Jeddah, Western Saudi Arabia [PDF]

, 2010
Background There is little published on current Saudi diabetic patients' practices when they are exposed to foot disorders such as open wound, ulcer, and skin cracks. These factors are usually influenced by local culture and communities beliefs.
Balkees A Bakhotmah, Hasan A Alzahrani
core   +2 more sources

Diabetic Foot Ulcer [PDF]

, 2013
It is estimated that approximately 15% of diabetic people world-wide will at some stage develop diabetic foot ulceration. The prevalence of active foot ulceration varies from approx‐ imately 1% in certain European and North American studies to more than 11% in reports from some African countries (table 1).
Farzamfar, Bardia, Nazari, Reza, Bayanolhagh, Saeed   +2 more
openaire   +2 more sources