Results 171 to 180 of about 337,805 (310)

Diabetic Kidney Disease Update. [PDF]

J Diabetes
Mende C, Bloomgarden Z.
europepmc   +1 more source

Expression Profile of Urinary Exosomal miRNAs in Patients With Diabetic Kidney Disease and Their Association With Kidney Damage

Juan Li, Lulu Han, Ting Wang, Lin Yang, Hong Zhou   +4 more
openalex   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Gut microbiota: an important player in diabetic kidney disease. [PDF]

Diabetol Metab Syndr
Shi P, Chen L.
europepmc   +1 more source

CerS6 links ceramide metabolism to innate immune responses in diabetic kidney disease

Zijing Zhu, Yun Cao, Yonghong Jian, Hongtu Hu, Qian Yang, Yiqun Hao, Huidi Jiang, Zilv Luo, Xueyan Yang, Weiwei Li, Jijia Hu, Hongyan Liu, Wei Liang, Guohua Ding, Zhaowei Chen   +14 more
openalex   +1 more source

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

Advanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli, Daniel Levy, Alyssa Schledwitz, Natalia Sampaio Moura, Mitali Sarkar, Talia J. Solomon, Emily H. Powsner, Raith Nowak, Zuzanna Mamczarz, Christopher J. Bridgeman, Sulayman Khan, Andrew Hui, Nidhi Anne, Laura Reus, William E. Bentley, Jean‐Pierre Raufman, Steven M. Jay   +16 more
wiley   +1 more source

Unraveling the role of mitochondrial dysfunction in diabetic kidney disease: insights and interventions. [PDF]

Front Pharmacol
Fan Z, Luo P, Gao Y, Ma H, Fan J, Sanan S, Zhang P, Lu K, Xia H.   +8 more
europepmc   +1 more source

MicroRNAs: new biomarkers and promising therapeutic targets for diabetic kidney disease

, 2019
Linicene Rosa do Nascimento, Caroline Pereira Domingueti   +1 more
openalex   +1 more source

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

Advanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao, Zhihao Wang, Shasha Tang, Yuan Fang, Guiling Yu, Xiaoting Qiu, Lingxue Niu, Tao Yan, Xingwan Liu, Xiaoding Ma, Deqiang Kong, Yang Zhou, Ningzi Guan, Jinzhong Tian, Meiyan Wang, Haifeng Ye, Fengfeng Cai   +16 more
wiley   +1 more source

Unveiling the gut-kidney dialogue in diabetic kidney disease. [PDF]

World J Diabetes
Gembillo G, Soraci L, Visconti L.
europepmc   +1 more source