Results 91 to 100 of about 13,469 (305)

Novel role of parathyroid hormone-related protein in the pathophysiology of the diabetic kidney: Evidence from experimental and human diabetic nephropathy [PDF]

, 2013
Parathyroid hormone-related protein (PTHrP) and its receptor type 1 (PTH1R) are extensively expressed in the kidney, where they are able to modulate renal function. Renal PTHrP is known to be overexpressed in acute renal injury. Recently, we hypothesized
Arenas, María Isabel, Bosch, Ricardo J., Bover, Jordi, Esbrit, Pedro, Izquierdo, Adriana, Olea, Nuria, Ortega, Arantxa, Romero, Montserrat   +7 more
core   +4 more sources

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Intravascular Lithotripsy Is Associated With Superior Clinical Outcomes Compared to Atherectomy: A Large‐Scale, Propensity‐Matched Analysis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary artery disease (CAD) with severe calcification remains a growing challenge in percutaneous coronary intervention (PCI). Atherectomy (ATH) has long been used for plaque modification, whereas intravascular lithotripsy (IVL) has emerged as a promising alternative. Large‐scale comparative data on long‐term outcomes are limited.
Charles D. Miks, Grant K. Ozaki, Chirayu R. Shukla, Vikram Sharma   +3 more
wiley   +1 more source

A Primer on Quality Assurance and Performance Improvement for Interprofessional Chronic Kidney Disease Care: A Path to Joint Commission Certification. [PDF]

, 2019
Interprofessional care for chronic kidney disease facilitates the delivery of high quality, comprehensive care to a complex, at-risk population. Interprofessional care is resource intensive and requires a value proposition. Joint Commission certification
Awdishu, Linda, Moore, Teri, Morrison, Michelle, Trzebinska, Danuta, Turner, Christy   +4 more
core   +1 more source

A Stacked Ensemble Multi‐Label Model for Predicting Co‐Occurring Microvascular and Macrovascular Complications in Type 2 Diabetes

Chronic Diseases and Translational Medicine, EarlyView.
Feature importance for predicting multiple diabetes complications based on a Stacking‐Classifier Chain model. Abstract Background Type 2 diabetes mellitus (T2DM) leads to severe microvascular and macrovascular complications. Traditional single‐label prediction models fail to capture their co‐occurring nature.
Maryam Zamani, Maryam Farhadian, Nasrin Piran, Shiva Borzouei   +3 more
wiley   +1 more source

Characterization of diabetic patients with Microalbuminuria

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
Background: diabetic nephropathy is the cause of 10 to 15 % of chronically ill terminal patients and a significant percentage are diagnosed in very advanced stages.Objective: to characterize, from the clinical and epidemiological point of view, the ...
Pilar Laborí Quesada, Alberto Mario Laborí Gallego, Miriam Velázquez Reyes, Alina Dolores Leyva Rojas, Lidia Silvia Sosa Ramos   +4 more
doaj  

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source

Clinical Profile and Risk Factors for Complication of Type 2 Diabetes Mellitus at the National Referral Hospital, Bhutan: A Descriptive Cross‐Sectional Study

Health Science Reports
Background and Aim Globally, diabetes mellitus is a major public health concern affecting 10.5% of the population. Nearly 90% of these people have Type 2 diabetes mellitus (T2DM). In Bhutan, T2DM is prevalent in 5.6% of the population, and around 60% are
Tshering Norbu, Yeshey Dorjey, Sangay Tshering, Namkha Dorji, Guru Prasad Dhakal   +4 more
doaj   +1 more source

Meta-analysis of the Efficacy and Safety of Finerenone in the Treatment of Type 2 Diabetic Nephropathy [PDF]

Zhongguo quanke yixue
Background Finerenone, a nonsteroidal mineralocorticoid antagonist, is a novel therapeutic agent for renal protection in patients with diabetic kidney disease, joining the ranks of angiotensin-converting enzyme inhibitors and sodium-glucose cotransporter
ADILI Tuersun, CHENG Gang
doaj   +1 more source

Poboljšanje krvnog tlaka, cirkadijalnog ritma i proteinurije u bolesnika s kroničnom bubrežnom bolešću nakon postupka denervacije bubrežnih arterija [PDF]

, 2015
Renal sympathetic denervation (RSD) could be an effective antihypertensive treatment of resistant hypertension that triggers additional positive effects on glucose metabolism and insulin sensitivity in type 2 diabetes mellitus.
Gordana Cavrić, Ingrid Prkačin, Tomislav Bulum, Valentina Ćorić-Martinović, Vesna Đermanović-Dobrota, Vinko Vidjak   +5 more
core   +1 more source