Results 131 to 140 of about 306,917 (239)

Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy

VIEW, EarlyView.
This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley   +1 more source

Temporal Trends in Pregnancy Outcomes Among Parents With Type 1 Diabetes: A Nationwide Register‐Based Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To assess temporal trends in outcomes of pregnancies with maternal or paternal type 1 diabetes compared to the general population. Design Register‐based study. Setting Denmark. Population 1 551 893 pregnancies from 1997 to 2021, hereof 5478 with maternal and 8072 with paternal type 1 diabetes.
Tina Wullum Gundersen, Sine Knorr, Lene Ringholm, Dorte Moeller Jensen, Peter Damm, Karoline Kragelund Nielsen, Helena Backman, Jeannet Lauenborg, Elisabeth Reinhardt Mathiesen, Anne Helby Petersen, Niels Skipper, Allan Kofoed‐Enevoldsen, Tine Dalsgaard Clausen   +12 more
wiley   +1 more source

Hypertensive Disorders of Pregnancy and the Long‐Term Risk of Maternal Retinal and Ophthalmic Disease: A Systematic Review and Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Hypertensive disorders of pregnancy (HDP) are associated with increased long‐term risk of maternal cardio‐metabolic disease, but links with future retinal diseases remain unclear. Objective The objective of this study is to synthesise the published literature on HDP and subsequent retinal and other ophthalmic disease.
Peter Barrett, Cian Carey, Sinéad O'Riordan, Angela Ding Wu, Emma Wallace, Matilda Biba, Karolina Kublickiene, Fergus McCarthy, Ali Khashan   +8 more
wiley   +1 more source

Text mining for case report articles on “peritoneal dialysis” from PubMed database

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 459-470, June 2025.
Abstract Introduction The number of published medical articles on peritoneal dialysis (PD) has been increasing, and efficiently selecting information from numerous articles can be difficult. In this study, we examined whether artificial intelligence (AI) text mining can be a good support for efficiently collecting PD information.
Kazuhiko Fukushima, Kenji Tsuji, Hiroyuki Nakanoh, Naruhiko Uchida, Soichiro Haraguchi, Shinji Kitamura, Jun Wada   +6 more
wiley   +1 more source

Impact of barometric pressure on blood pressure during dialysis: Introducing intradialytic time‐averaged cumulative systolic blood pressure (TACsBP‐inD) as a new metric

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 525-534, June 2025.
Abstract Background Blood pressure is a crucial risk factor for hemodialysis patients, but the specific impact of weather factors, particularly barometric pressure, on blood pressure remains unclear. This study aims to examine the relationship between barometric pressure and blood pressure in hemodialysis patients. Methods We conducted a single‐center,
Kosaku Iwatsubo, Shouichi Fujimoto, Michikazu Nakai   +2 more
wiley   +1 more source

The Renoprotective Effects of Sodium Valproate as a Histone Deacetylase Inhibitor on Diabetic Nephropathy

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2017
BACKGROUND AND OBJECTIVE: Diabetic nephropathy (DN), as the most common cause of end-stage renal failure, caused by protein kinase C pathway and reactive oxygen species.
R Ataee, H Esmaeeli
doaj  

Rutaecarpine Improves Hyperlipidemia‐Related Erectile Dysfunction in Rats by Inhibiting Macrophage M1 Polarization‐Induced Corpus Cavernosum Fibrosis

Andrology, EarlyView.
ABSTRACT Background Hyperlipidemia‐related erectile dysfunction (HLED) responds poorly to first‐line treatments such as phosphodiesterase type 5 inhibitors (PDE5Is), emphasizing the need for alternative therapeutic strategies. Rutaecarpine (RUT), a bioactive alkaloid, exhibits significant anti‐inflammatory and anti‐fibrotic effects.
Bocheng Tu, Shiqing Zhu, Peng Hu, Xiaoyu Zhu, Jiaxin Wang, Xinqi Liu, Sen Fu, Tao Wang, Jihong Liu, Kai Cui   +9 more
wiley   +1 more source

Inter‐eye microvascular asymmetry across stages of diabetic retinopathy: An OCT angiography study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate inter‐eye asymmetry in macular microvascular parameters across different stages of diabetic retinopathy (DR) using OCT angiography, and to explore the associations with clinical factors. Methods This cross sectional study included 442 eyes of 221 patients with diabetes mellitus type 2. Central subfield thickness (CST), area
Stela Vujosevic, Sema Tamer Kaderli, Gabriele Piccoli, Elena Tagliabue, Camilla Alovisi, Vanda Bucceri, Emanuele Torti, Elisa Marenzi, Dogukan Ozen, Livio Luzi, Paolo Nucci   +10 more
wiley   +1 more source

Longitudinal progression of retinal nonperfusion in clinically stable diabetic retinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To longitudinally assess and quantify changes in retinal nonperfusion (NP) in clinically stable diabetic retinopathy (DR) using ultra‐widefield fluorescein angiography (UWF‐FA) and optical coherence tomography angiography (OCTA). Methods Fifty‐one eyes from thirty‐three patients were followed for a mean of 15.9 ± 11.4 months.
Stela Vujosevic, Sofia Ginelli, Alessandra Cernuschi, Celeste Limoli, Gabriele Piccoli, Elena Tagliabue, Emanuele Torti, Paolo Nucci, Paolo S. Silva   +8 more
wiley   +1 more source

Inflammatory Bowel Disease Is Associated With an Increased Risk of End‐Stage Renal Disease: A Population‐Based Cohort Study

Alimentary Pharmacology &Therapeutics, EarlyView.
In a retrospective population‐based cohort study using the University of Manitoba IBD Epidemiology Database, persons with IBD have an increased risk of ESRD by nearly 50%, with CD showing greater risk than UC. Bowel surgery, allopurinol use and oral steroid therapy are important predictors, emphasising the necessity of careful renal monitoring in IBD ...
Onuma Sattayalertyanyong, Zoann Nugent, Bryce Barr, Keevin N. Bernstein, Charles N. Bernstein   +4 more
wiley   +1 more source