Results 151 to 160 of about 683,288 (403)

Rapid Prototyping Model for Healthcare Alternative Payment Models: Replicating the Federally Qualified Health Center Advanced Primary Care Practice Demonstration [PDF]

open access: yesarXiv, 2018
Innovation in healthcare payment and service delivery utilizes high cost, high risk pilots paired with traditional program evaluations. Decision-makers are unable to reliably forecast the impacts of pilot interventions in this complex system, complicating the feasibility assessment of proposed healthcare models.
arxiv  

Lean ZSF1 rats in basic research on heart failure with preserved ejection fraction

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1474-1478, April 2025.
Abstract Aims ZSF1 obese rats harbouring two mutant leptin receptor alleles (Leprcp and Leprfa) develop metabolic syndrome and heart failure with preserved ejection fraction (HFpEF), making them a widely used animal model in cardiometabolic research.
Petra Büttner   +10 more
wiley   +1 more source

Effect of high dose ramipril with or without indomethacin on glomerular selectivity [PDF]

open access: yes, 2002
Background. Despite the accumulating evidence of their efficacy, angiotensin-converting enzyme inhibitors (ACEi) still provide imperfect renoprotection.
Remuzzi, Andrea
core   +1 more source

The clinicopathological characteristics and prognosis of diabetic nephropathy in Tibetan area

open access: yesLinchuang shenzangbing zazhi, 2020
Objective To analyze and summarize the clinicopathological characteristics and prognosis of diabetic nephropathy(DN)in Tibetan area.Methods Patients with biopsy-confirmed DN at Tibet Autonomous Region People’s Hospital from April 2016 to December 2019 ...
HE Yan   +7 more
doaj  

Construction of a simulation model and evaluation of the effect of potential interventions on the incidence of diabetes and initiation of dialysis due to diabetic nephropathy in Japan

open access: yesBMC Health Services Research, 2017
Background The prevalence of diabetes mellitus is a growing public health concern in Japan. We developed a simulation model to predict the number of people with diabetes and those on dialysis due to diabetic nephropathy. In addition, we used the model to
Takehiro Sugiyama   +4 more
doaj   +1 more source

Effect of Finerenone on Albuminuria in Patients With Diabetic Nephropathy: A Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2015
IMPORTANCE Steroidal mineralocorticoid receptor antagonists, when added to a renin-angiotensin system blocker, further reduce proteinuria in patients with chronic kidney disease but may be underused because of a high risk of adverse events.
G. Bakris   +14 more
semanticscholar   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen   +7 more
wiley   +1 more source

Diabetic nephropathy

open access: yesDisease-a-Month, 1998
Diabetic nephropathy is the most common cause of end-stage renal disease (ESRD) and accounts for 35% of the ESRD population in the United States. It results in considerable morbidity, mortality, and expense. The average cost of managing one diabetic patient with ESRD is approximately $50,000 a year.
openaire   +2 more sources

The Heart and Diabetic Nephropathy

open access: yesMethodist DeBakey Cardiovascular Journal, 2010
BACKGROUND Diabetic nephropathy represents the most common etiology for stage 5 chronic kidney disease in the United States, resulting in the need for dialysis and transplantation. It is estimated that about one-third of U.S. patients who need renal replacement therapy are diabetics.
Juan Jorge Olivero   +3 more
openaire   +4 more sources

The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes.

open access: yesNew England Journal of Medicine, 2001
BACKGROUND Microalbuminuria and hypertension are risk factors for diabetic nephropathy. Blockade of the renin-angiotensin system slows the progression to diabetic nephropathy in patients with type 1 diabetes, but similar data are lacking for hypertensive
H. Parving   +5 more
semanticscholar   +1 more source

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