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Proteomics and Diabetic Nephropathy

Seminars in Nephrology, 2005
Diabetes mellitus is acknowledged to be a group of metabolic diseases and heterogeneous in natural history, pathogenesis, response to treatment, and disease progression and remission. Diabetic nephropathy (DN) accounts for approximately 40% of all newly diagnosed cases of end-stage renal disease.
Michael L, Merchant, Jon B, Klein
openaire   +3 more sources

Diabetic Nephropathy and Pregnancy

Clinical Obstetrics and Gynecology, 1991
Knowledge of the pathogenic mechanisms of diabetic nephropathy (by which hyperglycemia, hyperfiltration, and hypertension cause the gradual development of microproteinuria, mesangial expansion, and eventual glomerular closure) provides the basis for effective treatment.
C A, Combs, J L, Kitzmiller
openaire   +3 more sources

Diabetic nephropathy

Irish Journal of Medical Science, 1979
Since the original recognition by Kimmelstiel and Wilson in 1936 of a characteristic nodular lesion in diabetic renal glomeruli, no simple relationship has been demonstrated between the structural and functional defects now known to exist in diabetic renal disease.
openaire   +2 more sources

PROGRESSION OF DIABETIC NEPHROPATHY

The Lancet, 1979
Although deterioration of renal function in diabetic nephropathy varies considerably from one diabetic to another, its rate is constant in individuals. For each patient there is a linear relation between period (months) which elapses from the time serum creatinine becomes greater than 200 mumol/l and the inverse the inverse of the serum-creatinine. The
R H, Jones   +4 more
openaire   +2 more sources

Smoking and Diabetic Nephropathy

Acta Medica Scandinavica, 2009
Forty-seven patients with insulin-dependent diabetes (IDDM) and diabetic nephropathy and 47 controls with IDDM without diabetic nephropathy were interviewed about their previous and current smoking habits. The patients in the two groups were matched according to sex, age, age at onset, and duration of diabetes. All patients in the nephropathy group had
G, Nordén, G, Nyberg
openaire   +2 more sources

The pathogenesis of diabetic nephropathy

Nature Clinical Practice Endocrinology & Metabolism, 2008
Between 20% and 40% of patients with diabetes ultimately develop diabetic nephropathy, which in the US is the most common cause of end-stage renal disease requiring dialysis. Diabetic nephropathy has several distinct phases of development and multiple mechanisms contribute to the development of the disease and its outcomes.
Suma, Dronavalli   +2 more
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Diabetes and nephropathy is not always equal to diabetic nephropathy

The British Journal of Diabetes & Vascular Disease, 2013
In a busy diabetes clinic, it is always easy for the diabetologist to equate nephropathy and diabetes to “diabetic nephropathy”. Certain clinical clues should arouse suspicion of non-diabetic renal disease as this may have important implications in patient management.
Krishnan Swaminathan   +3 more
openaire   +1 more source

Losartan in diabetic nephropathy

Expert Review of Cardiovascular Therapy, 2004
Diabetic nephropathy has become the single most important cause of end-stage renal disease in the USA, Europe and Japan. The earliest marker of incipient diabetic nephropathy is the transition of normoalbuminuria to microalbuminuria at an albumin excretion rate of 20 microg/min.
Norberto, Perico   +2 more
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Diabetic Nephropathy: An Overview

2019
Diabetic nephropathy (DN) is one of the most feared diabetic chronic microvascular complications and the major cause of end-stage renal disease (ESRD). The classical presentation of DN is characterized by hyperfiltration and albuminuria in the early phases which is then followed by a progressive renal function decline.
Sagoo, Manpreet K., Gnudi, Luigi
openaire   +3 more sources

Nephropathy in Diabetes

Experimental and Clinical Endocrinology & Diabetes, 2023
Ludwig, Merker   +3 more
openaire   +2 more sources

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