Results 151 to 160 of about 463,148 (204)
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Clinical Cornerstone, 2003
As the epidemic of diabetes spreads so does the number of patients at risk for developing diabetic nephropathy, which occurs in 20% to 40% of all diabetic patients. Indeed, diabetes is the most common cause of end-stage renal disease (ESRD) in the United States, accounting for > 40% of patients starting renal replacement therapy each year ...
Mark E, Molitch +5 more
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As the epidemic of diabetes spreads so does the number of patients at risk for developing diabetic nephropathy, which occurs in 20% to 40% of all diabetic patients. Indeed, diabetes is the most common cause of end-stage renal disease (ESRD) in the United States, accounting for > 40% of patients starting renal replacement therapy each year ...
Mark E, Molitch +5 more
openaire +4 more sources
Diabetes Technology & Therapeutics, 1999
Renal involvement is one of the major microvascular complications of both type 1 and type 2 diabetes mellitus. Diabetic nephropathy is the major cause of end-stage renal failure in most Western nations and is associated with increased morbidity and mortality as compared to other causes of renal disease. The pathogenesis of renal involvement in diabetes
G, Boner, M E, Cooper
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Renal involvement is one of the major microvascular complications of both type 1 and type 2 diabetes mellitus. Diabetic nephropathy is the major cause of end-stage renal failure in most Western nations and is associated with increased morbidity and mortality as compared to other causes of renal disease. The pathogenesis of renal involvement in diabetes
G, Boner, M E, Cooper
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Current Opinion in Internal Medicine, 2003
Diabetic nephropathy is the single most common disorder leading to renal failure. Its annual incidence has more than doubled in the past decade to reach 44% of all end-stage renal disease, despite recent therapeutic advances. Thus, research into diabetic nephropathy pathophysiology that could lead to new treatment approaches is urgently needed and this
M Luiza, Caramori, Michael, Mauer
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Diabetic nephropathy is the single most common disorder leading to renal failure. Its annual incidence has more than doubled in the past decade to reach 44% of all end-stage renal disease, despite recent therapeutic advances. Thus, research into diabetic nephropathy pathophysiology that could lead to new treatment approaches is urgently needed and this
M Luiza, Caramori, Michael, Mauer
openaire +2 more sources
Pyroptosis in diabetes and diabetic nephropathy
Clinica Chimica Acta, 2022Pyroptosis is identified as a pro-inflammatory programmed cell death, mediated by gasdermins (GSDMs) family of proteins accompanied by pro-inflammatory signals release. As essential players in innate immunity, inflammasomes are intracellular protein complexes which cleave gasdermin D (GSDMD), forming structurally stable pores in the cell membrane ...
Zhaohui, Cao +6 more
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Pediatric Clinics of North America, 1984
It is estimated that about 50 per cent of all patients with Type I diabetes mellitus develop uremia during the course of their disease. Glomerular microvasculopathy is the most serious and predictable threat to longevity. Following a discussion of this disorder, the author outlines a plan for overall management of each phase of kidney disease so that ...
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It is estimated that about 50 per cent of all patients with Type I diabetes mellitus develop uremia during the course of their disease. Glomerular microvasculopathy is the most serious and predictable threat to longevity. Following a discussion of this disorder, the author outlines a plan for overall management of each phase of kidney disease so that ...
openaire +2 more sources
Current therapy in endocrinology and metabolism, 1997
Diabetic nephropathy accounts for almost a third of all causes of ESRD. Microalbuminuria screening among diabetics can offer early detection of incipient nephropathy. Aggressive treatment with ACE inhibitors may delay the onset of overt renal failure or delay its progression.
CASTELLINO, Pietro +2 more
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Diabetic nephropathy accounts for almost a third of all causes of ESRD. Microalbuminuria screening among diabetics can offer early detection of incipient nephropathy. Aggressive treatment with ACE inhibitors may delay the onset of overt renal failure or delay its progression.
CASTELLINO, Pietro +2 more
openaire +6 more sources
Disease-a-Month, 1993
Diabetic nephropathy occurs in approximately 35% of all diabetic patients, both insulin and non-insulin dependent. It accounts for the largest proportion increase of all diseases as a cause for endstage renal disease in the United States. Certain populations, i.e., Pima Indians and Mexican and black Americans, have a higher propensity for developing ...
G L, Bakris, J H, Stein
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Diabetic nephropathy occurs in approximately 35% of all diabetic patients, both insulin and non-insulin dependent. It accounts for the largest proportion increase of all diseases as a cause for endstage renal disease in the United States. Certain populations, i.e., Pima Indians and Mexican and black Americans, have a higher propensity for developing ...
G L, Bakris, J H, Stein
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2012
The most common cause of end stage renal disease (ESRD) requiring dialysis is diabetes. Both environmental and genetic factors have been postulated as the risk factors of Diabetic Nephropathy (DN). Hyperglycemia-induced metabolic and hemodynamic pathways are recognized to be mediators of kidney injury. Multiple biochemical pathways have been postulated
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The most common cause of end stage renal disease (ESRD) requiring dialysis is diabetes. Both environmental and genetic factors have been postulated as the risk factors of Diabetic Nephropathy (DN). Hyperglycemia-induced metabolic and hemodynamic pathways are recognized to be mediators of kidney injury. Multiple biochemical pathways have been postulated
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Archives of Family Medicine, 1996
Diabetic nephropathy is an important microvascular complication of both insulin-dependent and non-insulin-dependent diabetes mellitus. It is the leading cause of end-stage renal disease. The natural course, pathogenesis, clinical evaluation, and treatment of diabetic nephropathy were reviewed, with special emphasis on recent important studies of ...
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Diabetic nephropathy is an important microvascular complication of both insulin-dependent and non-insulin-dependent diabetes mellitus. It is the leading cause of end-stage renal disease. The natural course, pathogenesis, clinical evaluation, and treatment of diabetic nephropathy were reviewed, with special emphasis on recent important studies of ...
openaire +2 more sources