Results 151 to 160 of about 432,036 (307)

The Therapeutic Effects of Sevelamer on Blood Sugar, HbA1c, Lipid Profile, and hs-CRP in Patients with Diabetic Nephropathy [PDF]

Background: Diabetic nephropathy (DN) is one of the major complications of diabetes. Hyperglycemia, inflammation and oxidative stress as well as advanced glycation end products (AGEs) are reported as the risk factors for DN. Sevelamer has shown promising
محمدی کبار, سوسن, فکری نوده, حسین, ایرانپرور, منوچهر, شرقی, افشان, بشردوست, بهمن, حبیب زاده, افشین   +5 more
core  

Inter‐eye microvascular asymmetry across stages of diabetic retinopathy: An OCT angiography study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate inter‐eye asymmetry in macular microvascular parameters across different stages of diabetic retinopathy (DR) using OCT angiography, and to explore the associations with clinical factors. Methods This cross sectional study included 442 eyes of 221 patients with diabetes mellitus type 2. Central subfield thickness (CST), area
Stela Vujosevic, Sema Tamer Kaderli, Gabriele Piccoli, Elena Tagliabue, Camilla Alovisi, Vanda Bucceri, Emanuele Torti, Elisa Marenzi, Dogukan Ozen, Livio Luzi, Paolo Nucci   +10 more
wiley   +1 more source

Inflammatory Bowel Disease Is Associated With an Increased Risk of End‐Stage Renal Disease: A Population‐Based Cohort Study

Alimentary Pharmacology &Therapeutics, EarlyView.
In a retrospective population‐based cohort study using the University of Manitoba IBD Epidemiology Database, persons with IBD have an increased risk of ESRD by nearly 50%, with CD showing greater risk than UC. Bowel surgery, allopurinol use and oral steroid therapy are important predictors, emphasising the necessity of careful renal monitoring in IBD ...
Onuma Sattayalertyanyong, Zoann Nugent, Bryce Barr, Keevin N. Bernstein, Charles N. Bernstein   +4 more
wiley   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Luteolin Alleviates Diabetic Nephropathy Fibrosis Involving AMPK/NLRP3/TGF-β Pathway [PDF]

Rong Huang,1,* Jun Zeng,1,* Xiaoze Yu,1 Yunke Shi,2 Na Song,1 Jie Zhang,1 Peng Wang,1 Min Luo,1 Yiming Ma,2 Chuang Xiao,1 Lueli Wang,1 Guanhua Du,3 Hongyan Cai,4 Weimin Yang1 1School of Pharmaceutical Science & Yunnan Key Laboratory of ...
Zhang J, Ma Y, Huang R, Cai H, Shi Y, Wang L, Yang W, Song N, Wang P, Luo M, Zeng J, Du G, Xiao C, Yu X   +13 more
core  

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

Urinary podocalyxin as an early biomarker for diabetic nephropathy. [PDF]

PLoS One
Hossain MS, Dwipi ST, Ahmed N, Murshed KM, Aftab KA, Al Mahdi A, Hoque MM, Taraq MJH, Hussain MZ, Azad MAK.   +9 more
europepmc   +1 more source

Optimising Haematopoietic Stem Cell Transplantation: Enhancing Myeloablation Sensitivity and Alleviating Anaemia Using Roxadustat (FG‐4592)

Cell Proliferation, EarlyView.
The use of FG‐4592 in the process of myeloablation can promote haematopoietic cell apoptosis for more effective myeloablation, maintain the number of RBC and may create a pluripotent microenvironment suitable for donor cells, so as to enable more effective haematopoietic reconstruction of donor cells in vivo.
Guanheng Yang, Jiahui Wu, Xinbing Guo, Wenchen Shen, Xiao Sang, Xiuli Gong, Shu‐Zhen Huang, Jingzhi Zhang, Fanyi Zeng   +8 more
wiley   +1 more source

Microvascular damage in diabetic nephropathy and the subsequent risk of Alzheimer's disease: a systematic review. [PDF]

Ann Med Surg (Lond)
Mohammed N, Alyazan Khalil Taher Al-Jabali T, Yassien N, Osman Abufatima I, Omer Ibrahim Ahmed F, El Yazal S, Satti W, Alalamat N, Aamer Abkar Ibrahim M, Tirelbar B, Paudel L, Abdalla Abdelsadig Mahmoud I, Humdi L, Ali H, Hammad Jaber Amin M, Abdelrahman N.   +15 more
europepmc   +1 more source

Targeting CKIP‐1 for Disease Therapy: Cellular Functions, Molecular Networks, and Clinical Potential

Cell Proliferation, EarlyView.
CKIP‐1, as a scaffold protein with special structural domains, treats related diseases through multiple emerging targeted technologies.
Xin Huang, Shijie Lv, Lejia Li, Jirong Xie, Zhengguo Cao   +4 more
wiley   +1 more source